The relationship between clinical diagnosis and histopathological diagnosis in oral and maxillofacial lesions: a retrospective study of 200 cases

Halil İbrahim Durmuş; Ümit Solmaz; Kağan Fatih Kuşan; Nuran Dağ; Tevfik Kızılseki

The relationship between clinical diagnosis and histopathological diagnosis in oral and maxillofacial lesions: a retrospective study of 200 cases

Abstract

Aims: The aim of this study was to evaluate the demographic characteristics and histopathological distribution of lesions in biopsy samples taken from the oral and maxillofacial regions, and to investigate the relationship between clinical preliminary diagnosis and histopathological diagnosis. Methods: In this retrospective study, data from 200 patients who underwent biopsy at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, between 1 June 2025 and 15 February 2026 were analysed. Age, gender, clinical preliminary diagnosis, and histopathological diagnosis were recorded. Histopathological diagnoses were grouped into cystic, inflammatory, and reactive lesions. Concordance between clinical preliminary and histopathological diagnoses was assessed using descriptive statistics and, where appropriate, the Chi-square test. Results: The mean age was 34.8±16.5 years; 59% of patients were female. Radicular cyst was the most common clinical preliminary diagnosis (n=134), whereas granulation tissue (n=76) and radicular cyst (n=64) were the most frequent histopathological diagnoses. The overall concordance rate between clinical preliminary and histopathological diagnoses was 58% (κ=0.32), indicating fair agreement. Many lesions clinically diagnosed as radicular cysts were histopathologically identified as granulation tissue. Cystic and inflammatory lesions constituted the majority, and no significant association was found between demographic variables and lesion types (p>0.05). Conclusion: Significant discrepancies may exist between clinical and histopathological diagnoses. Histopathological examination is indispensable for definitive diagnosis and appropriate treatment planning.

Keywords

References

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Details

Primary Language

English

Subjects

Oral and Maxillofacial Surgery

Journal Section

Research Article

Authors

Halil İbrahim Durmuş ^*
0000-0003-4762-4788
Türkiye

Ümit Solmaz
0000-0001-7686-8613
Türkiye

Kağan Fatih Kuşan
0009-0007-0080-8703
Türkiye

Nuran Dağ
0009-0001-3845-8872
Türkiye

Tevfik Kızılseki
0009-0009-8173-0550
Türkiye

Publication Date

August 15, 2026

Submission Date

April 22, 2026

Acceptance Date

July 3, 2026

Published in Issue

Year 2026 Volume: 7 Number: 4

IZ

https://izlik.org/JA42HJ95CM

Cite

RIS / Bibtex

APA

Durmuş, H. İ., Solmaz, Ü., Kuşan, K. F., Dağ, N., & Kızılseki, T. (2026). The relationship between clinical diagnosis and histopathological diagnosis in oral and maxillofacial lesions: a retrospective study of 200 cases. Journal of Medicine and Palliative Care, 7(4), 704-709. https://izlik.org/JA42HJ95CM

AMA

1.Durmuş Hİ, Solmaz Ü, Kuşan KF, Dağ N, Kızılseki T. The relationship between clinical diagnosis and histopathological diagnosis in oral and maxillofacial lesions: a retrospective study of 200 cases. J Med Palliat Care / JOMPAC / jompac. 2026;7(4):704-709. https://izlik.org/JA42HJ95CM

Chicago

Durmuş, Halil İbrahim, Ümit Solmaz, Kağan Fatih Kuşan, Nuran Dağ, and Tevfik Kızılseki. 2026. “The Relationship Between Clinical Diagnosis and Histopathological Diagnosis in Oral and Maxillofacial Lesions: A Retrospective Study of 200 Cases”. Journal of Medicine and Palliative Care 7 (4): 704-9. https://izlik.org/JA42HJ95CM.

EndNote

Durmuş Hİ, Solmaz Ü, Kuşan KF, Dağ N, Kızılseki T (August 1, 2026) The relationship between clinical diagnosis and histopathological diagnosis in oral and maxillofacial lesions: a retrospective study of 200 cases. Journal of Medicine and Palliative Care 7 4 704–709.

IEEE

[1]H. İ. Durmuş, Ü. Solmaz, K. F. Kuşan, N. Dağ, and T. Kızılseki, “The relationship between clinical diagnosis and histopathological diagnosis in oral and maxillofacial lesions: a retrospective study of 200 cases”, J Med Palliat Care / JOMPAC / jompac, vol. 7, no. 4, pp. 704–709, Aug. 2026, [Online]. Available: https://izlik.org/JA42HJ95CM

ISNAD

Durmuş, Halil İbrahim - Solmaz, Ümit - Kuşan, Kağan Fatih - Dağ, Nuran - Kızılseki, Tevfik. “The Relationship Between Clinical Diagnosis and Histopathological Diagnosis in Oral and Maxillofacial Lesions: A Retrospective Study of 200 Cases”. Journal of Medicine and Palliative Care 7/4 (August 1, 2026): 704-709. https://izlik.org/JA42HJ95CM.

JAMA

1.Durmuş Hİ, Solmaz Ü, Kuşan KF, Dağ N, Kızılseki T. The relationship between clinical diagnosis and histopathological diagnosis in oral and maxillofacial lesions: a retrospective study of 200 cases. J Med Palliat Care / JOMPAC / jompac. 2026;7:704–709.

MLA

Durmuş, Halil İbrahim, et al. “The Relationship Between Clinical Diagnosis and Histopathological Diagnosis in Oral and Maxillofacial Lesions: A Retrospective Study of 200 Cases”. Journal of Medicine and Palliative Care, vol. 7, no. 4, Aug. 2026, pp. 704-9, https://izlik.org/JA42HJ95CM.

Vancouver

1.Halil İbrahim Durmuş, Ümit Solmaz, Kağan Fatih Kuşan, Nuran Dağ, Tevfik Kızılseki. The relationship between clinical diagnosis and histopathological diagnosis in oral and maxillofacial lesions: a retrospective study of 200 cases. J Med Palliat Care / JOMPAC / jompac [Internet]. 2026 Aug. 1;7(4):704-9. Available from: https://izlik.org/JA42HJ95CM