The prognostic value of the 5-factor modified frailty index in patients with proximal femur fractures followed up in the postoperative intensive care unit: a retrospective cohort study

Berkay Küçük; Osman Yağız Atlı

The prognostic value of the 5-factor modified frailty index in patients with proximal femur fractures followed up in the postoperative intensive care unit: a retrospective cohort study

Abstract

Aims: Proximal femur fractures pose a major problem for geriatric patients due to both their increasing incidence and their adverse postoperative outcomes. Based on this, we aimed to demonstrate the prognostic value of the 5-factor modified frailty index (mFI-5) in patients with proximal femur fractures who were monitored in the postoperative intensive care unit (ICU) and to evaluate its relationship with clinical outcomes. Methods: This retrospective cohort study included 246 patients between August 2023 and February 2026. Demographic data, laboratory and clinical outcomes, and ICU and 90-day mortality rates were recorded. Receiver operating characteristic (ROC) curve analysis and logistic regression analysis were performed to assess the prognostic value of the mFI-5. Results: Twenty-seven patients (10.98%) died in the ICU. In patients with an mFI-5 score of ≥2, the need for vasopressors, invasive mechanical ventilation, and postoperative sepsis was significantly higher (p=0.008, p=0.01, and p=0.037, respectively). In addition, ICU mortality was also higher in this group (p=0.008). Upon examination of ROC curve analyses, the AUC value for mFI-5 was 0.706, and the cutoff value was 2 (p<0.001). In the multivariate logistic regression analysis, mFI-5 was also a strong independent risk factor for ICU mortality, with an odds ratio (OR) of 1.760 and p=0.033. Conclusion: The mFI-5 demonstrated an independent prognostic effect regarding poor clinical outcomes and mortality. Considering frailty indices in postoperative patients may offer opportunities for the early identification of critically ill patients and the prevention of complications.

Keywords

Ethical Statement

This study was approved by the Ankara Etlik City Hospital Scientific Research Evaluation and Ethics Committee No. 1 (Date: 15.04.2026, Decision No: AEŞH –BADEK1- 2026- 369).

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Details

Primary Language

English

Subjects

Intensive Care

Journal Section

Research Article

Authors

Berkay Küçük ^*
0000-0002-5166-1429
Türkiye

Osman Yağız Atlı
0000-0001-6657-6860
Türkiye

Publication Date

August 15, 2026

Submission Date

June 28, 2026

Acceptance Date

July 27, 2026

Published in Issue

Year 2026 Volume: 7 Number: 4

IZ

https://izlik.org/JA72ZK85UE

Cite

RIS / Bibtex

APA

Küçük, B., & Atlı, O. Y. (2026). The prognostic value of the 5-factor modified frailty index in patients with proximal femur fractures followed up in the postoperative intensive care unit: a retrospective cohort study. Journal of Medicine and Palliative Care, 7(4), 804-812. https://izlik.org/JA72ZK85UE

AMA

1.Küçük B, Atlı OY. The prognostic value of the 5-factor modified frailty index in patients with proximal femur fractures followed up in the postoperative intensive care unit: a retrospective cohort study. J Med Palliat Care / JOMPAC / jompac. 2026;7(4):804-812. https://izlik.org/JA72ZK85UE

Chicago

Küçük, Berkay, and Osman Yağız Atlı. 2026. “The Prognostic Value of the 5-Factor Modified Frailty Index in Patients With Proximal Femur Fractures Followed up in the Postoperative Intensive Care Unit: A Retrospective Cohort Study”. Journal of Medicine and Palliative Care 7 (4): 804-12. https://izlik.org/JA72ZK85UE.

EndNote

Küçük B, Atlı OY (August 1, 2026) The prognostic value of the 5-factor modified frailty index in patients with proximal femur fractures followed up in the postoperative intensive care unit: a retrospective cohort study. Journal of Medicine and Palliative Care 7 4 804–812.

IEEE

[1]B. Küçük and O. Y. Atlı, “The prognostic value of the 5-factor modified frailty index in patients with proximal femur fractures followed up in the postoperative intensive care unit: a retrospective cohort study”, J Med Palliat Care / JOMPAC / jompac, vol. 7, no. 4, pp. 804–812, Aug. 2026, [Online]. Available: https://izlik.org/JA72ZK85UE

ISNAD

Küçük, Berkay - Atlı, Osman Yağız. “The Prognostic Value of the 5-Factor Modified Frailty Index in Patients With Proximal Femur Fractures Followed up in the Postoperative Intensive Care Unit: A Retrospective Cohort Study”. Journal of Medicine and Palliative Care 7/4 (August 1, 2026): 804-812. https://izlik.org/JA72ZK85UE.

JAMA

1.Küçük B, Atlı OY. The prognostic value of the 5-factor modified frailty index in patients with proximal femur fractures followed up in the postoperative intensive care unit: a retrospective cohort study. J Med Palliat Care / JOMPAC / jompac. 2026;7:804–812.

MLA

Küçük, Berkay, and Osman Yağız Atlı. “The Prognostic Value of the 5-Factor Modified Frailty Index in Patients With Proximal Femur Fractures Followed up in the Postoperative Intensive Care Unit: A Retrospective Cohort Study”. Journal of Medicine and Palliative Care, vol. 7, no. 4, Aug. 2026, pp. 804-12, https://izlik.org/JA72ZK85UE.

Vancouver

1.Berkay Küçük, Osman Yağız Atlı. The prognostic value of the 5-factor modified frailty index in patients with proximal femur fractures followed up in the postoperative intensive care unit: a retrospective cohort study. J Med Palliat Care / JOMPAC / jompac [Internet]. 2026 Aug. 1;7(4):804-12. Available from: https://izlik.org/JA72ZK85UE