Case Report
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Görme kaybı ve serebral apse ile seyreden geç tanı konan bir rinoorbitoserebral mukormikozis olgusu

Year 2022, Volume: 3 Issue: 1, 71 - 73, 24.03.2022
https://doi.org/10.47582/jompac.1007435

Abstract

Rino-orbito-serebral mukormikozis, Zygomycetes türü küf mantarlarının neden olduğu, mortalitesi ve morbidite oranı yüksek fırsatçı bir mantar enfeksiyonudur. Mukormikozis için en önemli risk faktörü kontrolsüz diyabet ve diyabetik ketoasidozdur. Bunun dışında; desferoksamin tedavisi, demir yüksekliği, immünosüpresif ilaçlar, kortikosteroid kullanımı diğer risk faktörleridir. Bu yazıda, geç tanı konulan rinoorbitoserebral mukormikozise bağlı olarak görme kaybı ve serebral apse gelişen 62 yaşında diyabetik bir erkek sunuldu. Hastaya cerrahi debridman ile birlikte lipozomal amfoterisin-B tedavisi uygulandı.

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References

  • Kara M, Erdogan H, Toroslu T, et al. Rhino-orbito-cerebral Mucormycosis: two case reports in the light of the literature. Kulak Burun Bogasz İhtis Derg 2015; 25: 295-301.
  • Sundaram C, Mahadevan A, Laxmi V, et al. Cerebral zygomycosis. Mycoses 2005; 48: 396-407.
  • Tatar EC,Sürenoğlu UA, Işık E, Tütüncü E, Korkmaz H. Rhino-orbital Mucormycosis with orbital abscess : a case report. Kulak Burun Bogaz İhtis Derg 2011; 21: 102-5.
  • Binder U, Maurer E, Flörl CL. Mucormycosis--from the pathogens to the disease. Clin Microbiol Infect 2014; 20: 60-6.
  • Chayakulkeeree M, Ghannoum MA, Perfect JR. Zygomycosis: the re-emerging fungal infection. Eur J Clin Microbiol Infect Dis 2006; 25: 215-29.
  • Günaydın S, Baştan B, Acar H, Çevik N, Çokar Ö. Tolosa-Hunt sendromu: iki olgu sunumu. Med Bull Haseki 2015; 53: 308-12.
  • Bačová E, Chovanec F, Makohusová M, et al. Invasive rhino-orbito-cerebral Mucormycosis in pediatric patient with acute leukemia. Klin Onkol Spring 2020; 33: 138-44.
  • Roden MM , Zaoutis TE, Buchanan WL, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 2005; 1: 634-53.
  • Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of Mucormycosis. Clin Infect Dis 2012; 54: S23-34.
  • Guerreiro CA, Nobrega JP, Carvalho MP. Orbito-rhino-cerebral phycomycosis (Mucormycosis): report of a case. Arq Neuropsiquiatr 1980; 38: 99-105.

A case of late diagnosed rhinoorbitocerebral mucormycosis with visual loss and cerebral abscess.

Year 2022, Volume: 3 Issue: 1, 71 - 73, 24.03.2022
https://doi.org/10.47582/jompac.1007435

Abstract

Rhino-orbito-cerebral Mucormycosis is an opportunistic fungal infection caused by Zygomycetes species mold fungi with a high mortality and morbidity rate. The most important risk factor for Mucormycosis is uncontrolled diabetes and diabetic ketoacidosis. Except this; desferoxamine treatment, high iron, immunosuppressive drugs, corticosteroid use are other risk factors. In this article, a 62-year-old diabetic man who developed vision loss and cerebral abscess due to late diagnosed rhinocerebral Mucormycosis was presented. The patient was treated with liposomal amphotericin-B with surgical debridement.

Project Number

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References

  • Kara M, Erdogan H, Toroslu T, et al. Rhino-orbito-cerebral Mucormycosis: two case reports in the light of the literature. Kulak Burun Bogasz İhtis Derg 2015; 25: 295-301.
  • Sundaram C, Mahadevan A, Laxmi V, et al. Cerebral zygomycosis. Mycoses 2005; 48: 396-407.
  • Tatar EC,Sürenoğlu UA, Işık E, Tütüncü E, Korkmaz H. Rhino-orbital Mucormycosis with orbital abscess : a case report. Kulak Burun Bogaz İhtis Derg 2011; 21: 102-5.
  • Binder U, Maurer E, Flörl CL. Mucormycosis--from the pathogens to the disease. Clin Microbiol Infect 2014; 20: 60-6.
  • Chayakulkeeree M, Ghannoum MA, Perfect JR. Zygomycosis: the re-emerging fungal infection. Eur J Clin Microbiol Infect Dis 2006; 25: 215-29.
  • Günaydın S, Baştan B, Acar H, Çevik N, Çokar Ö. Tolosa-Hunt sendromu: iki olgu sunumu. Med Bull Haseki 2015; 53: 308-12.
  • Bačová E, Chovanec F, Makohusová M, et al. Invasive rhino-orbito-cerebral Mucormycosis in pediatric patient with acute leukemia. Klin Onkol Spring 2020; 33: 138-44.
  • Roden MM , Zaoutis TE, Buchanan WL, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 2005; 1: 634-53.
  • Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of Mucormycosis. Clin Infect Dis 2012; 54: S23-34.
  • Guerreiro CA, Nobrega JP, Carvalho MP. Orbito-rhino-cerebral phycomycosis (Mucormycosis): report of a case. Arq Neuropsiquiatr 1980; 38: 99-105.
There are 10 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Case Report [en] Olgu Sunumu [tr]
Authors

Salih Cesur

Melek Sena Altun 0000-0002-5612-7305

Cigdem Ataman Hatipoglu 0000-0002-1104-8232

Şerife Altun Demircan 0000-0002-9295-4578

Selin Şenol 0000-0001-5801-1800

Ülkü Siyah 0000-0002-8068-1963

Sami Kınıklı 0000-0002-9661-7851

Hafize Nalan Güneş 0000-0002-9719-2330

Tahir Yoldaş 0000-0003-4950-9142

Project Number -
Publication Date March 24, 2022
Published in Issue Year 2022 Volume: 3 Issue: 1

Cite

AMA Cesur S, Altun MS, Ataman Hatipoglu C, Demircan ŞA, Şenol S, Siyah Ü, Kınıklı S, Güneş HN, Yoldaş T. Görme kaybı ve serebral apse ile seyreden geç tanı konan bir rinoorbitoserebral mukormikozis olgusu. J Med Palliat Care / JOMPAC / jompac. March 2022;3(1):71-73. doi:10.47582/jompac.1007435

TR DİZİN ULAKBİM and International Indexes (1d)

Interuniversity Board (UAK) Equivalency: Article published in Ulakbim TR Index journal [10 POINTS], and Article published in other (excuding 1a, b, c) international indexed journal (1d) [5 POINTS]



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