Substance use and memory impairments: a multidimensional review on neurological and cognitive effects

Year 2025, Volume: 6 Issue: 2, 159 - 166, 23.03.2025

Gün Pakyürek

https://doi.org/10.47582/jompac.1617224

Abstract

This study aimed to examine the relationship between substance use and memory disorders. This study also analyzed the biological effects of drug use on the brain and investigated the mechanisms by which these effects lead to impairment of memory function. Furthermore, the impact of various elements, including substance abuse, mental health conditions, hereditary susceptibility, and chronological age, was assessed. Substance use negatively affects memory and learning processes by causing functional impairments in critical regions such as the hippocampus and frontal lobe. Different substances cause specific damage to the memory. This review highlights how substance use can lead to permanent neurocognitive impairment, with effects varying according to substance type, duration of use, and individual factors. This underscores the importance of early intervention and preventive strategies. Multidisciplinary approaches are important in the prevention and management of these effects.

Keywords

Substance addiction, memory disorders, cognitive effects

Ethical Statement

Bu çalışma için etik izne gerek yoktur.

Madde kullanımının bellek bozuklukları üzerindeki etkisi: kanıtlar ve sonuçlarüzerine bir inceleme

Abstract

Bu çalışmanın amacı, madde kullanımı ve bellek bozuklukları arasındaki ilişkiyi incelemektir. Çalışmada madde kullanımının beyin üzerindeki biyolojik etkileri incelenmiş ve bu etkilerin bellek işlevinde bozulmaya yol açtığı mekanizmalar araştırılmıştır. Ayrıca, madde kullanımı, ruh sağlığı koşulları, kalıtsal yatkınlık ve kronolojik yaş gibi çeşitli unsurların bu sonuçlara etkisi değerlendirilmiştir. Madde kullanımı, hipokampus ve frontal lob gibi kritik bölgelerde işlevsel bozulmalara neden olarak bellek ve öğrenme süreçlerini olumsuz yönde etkilemektedir. Öte yandan, farklı maddelerin bellekte spesifik hasarlara neden olduğu bulunmuştur. Madde kullanımı bireylerin bilişsel ve nörolojik işlevlerini olumsuz etkileyebilmekte ve kalıcı nörobilişsel bozukluğa yol açabilmektedir. Etkiler maddenin türüne, kullanım süresine ve bireysel faktörlere bağlı olarak değişmektedir. Bu durum, erken müdahale ve önleme stratejilerinin önemini vurgulamaktadır. Bu etkilerin önlenmesi ve yönetimi için multidisipliner yaklaşımlar önerilmektedir.

Keywords

Madde bağımlılığı, bilişsel etkiler., bellek bozuklukları

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