Guillain-Barré sendromu ile komplike bir gebelikte normal doğum

Year 2018, , 143 - 144, 01.05.2018

Rabia Başer Açıkgöz

https://doi.org/10.28982/josam.380945

Cited By: 1

Abstract

Gebeliğin akut idiopatik polinöropatilerin (Guillain-Barré Sendromu) etyopatogenezi ve prognozuna belirgin bir etkisinin olmadığı düşünülmesine rağmen, özellikle ileri motor disfonksiyonlarla giden gebelerde değişik obstetrik yaklaşımlar önerilmektedir. Kliniğimizde 3. trimesterda başlayan akut idiopatik polinöropati tanısı alan intrapartum ve postpartum hiç bir maternal komplikasyon gelişmeden spontan vajinal yolla sağlıklı bir bebeğin doğması bu hastalarda konservatif bir obstetrik yaklaşımın yararlı olabileceğini düşündürmektedir. Hastanın sunumu, tanı, tedavi ve sonuçları ile birlikte literatür gözden geçirilecektir.

Keywords

Guillain-Barré sendromu, Hamilelik, Spontan vajinal doğum, İmmunoglobulin

Spontaneous vaginal delivery after a pregnancy complicated with Guillain-Barré syndrome

Abstract

Guillain-Barré syndrome (GBS) is a rarely encountered, acute autoimmune polyradiculoneuropathy which is usually severe and fulminant. Although it is considered not to have an impact on the prognosis of pregnancy, there is no consensus on its management particularly in pregnant women with advanced motor dysfunctions. Different obstetrical approaches have been suggested. Herein, we discussed a case, which has been diagnosed with GBS in the 3rd trimester in our clinic and gave birth to a healthy infant via spontaneous vaginal delivery without any intrapartum or postpartum maternal complication. Patient presentation, diagnosis, treatment and outcome as well of review of the literature will be discussed.

Keywords

Guillain-Barré syndrome, Pregnancy, Spontaneous vaginal delivery, Immunoglobulin

References

• 1. Hughes RA, Cornblath DR. Guillian Barre syndrome. Lancet. 2005;366:1653-66.
• 2. Guillain G, Barré JA, Strohl A. Radiculoneuritis syndrome with hyperalbuminosis of cerebrospinal fluid without cellular reaction. Notes on clinical features and graphs of tendon reflexes. 1999;150:24–32.
• 3. Yuki N, Hartung HP. Guillain-Barré syndrome. N Engl J Med. 2012;366:2294–304.
• 4. Chan LY, Tsui MH, Leung TN. Guillain-Barré Syndrome in Pregnancy. Acta Obstet Gynecol Scand. 2004;83:319-25.
• 5. Aminoff MF, Neurologic disorders, (in) Maternal Fetal Medicine; Principle and Practice (eds) Creasy RK, Rennik R. W-B. Saunders Company, Philadelphia, 1995;1071-1101.
• 6. Quinlan DJ, Moodlcy J, Lallo BJ: Guillain Barre Syndrome in pregnancy: A case report. S Afr Med J. 1988;73(10);611-12.
• 7. Gauticr PE, Hantscn P, Vekemans MC, et al. Intensive care management of Guillain-Barré syndrome during pregnancy Intensive Care Med. 1990;16(7):460–2.
• 8. Cetinkaya K, Atakan AR, Yapca OE, Ulvı H, Ozel L, et al. Guillain-Barre´Syndrome in Pregnancy. Case Report. 2010;7(1):53-7.
• 9. The Italian Guillain-Barre´ Study Group. The prognosis and main prognostic indicators of GuillainBarre´ syndrome: a multicentre prospective study of 297 patients. Brain. 1996;119:2053-61.
• 10. Luis D, Pacheco MD, Antonio F, et al. Guillain-Barré Syndrome in Pregnancy. Obstetrics & Gynecology. 2016;128(5):1105–10.