Böbrek berrak hücreli sarkom: Bir olgu hakkında

Abstract

Böbrek Berrak Hücreli Sarkom (SRCC), saldırganlığı, yüksek kemik metastatik potansiyeli ve tekrarlama eğilimi nedeniyle tanınan, çocuğun nadir görülen malign tümörüdür. Büyük bir sağ lomber kitle olan 22 aylık bir bebekte SRCC tanısı alan bir olgu sunuyoruz. Bu kitlenin tanısı bir anatomi-patoloji üzerine yerleştirilmiş şeffaf hücreli sarkomu olup, böbrek kitlesinin tanısı böbrek kanseri ile ilgili belirsiz kalmıştır. Histolojik özellik dışında, şu anda tanısı için bir kriter bulunmamaktadır. Yeni tedavi rejimlerinin uygulamaya konması ile prognozu belirgin bir şekilde artmıştır.

Keywords

• Tümör,Böbrek,Çocuk,Sarkoma,Berrak hücreler

Kidney clear cell sarcoma: About one case

Abstract

Kidney Clear Cell Sarcoma (SRCC) is a rare malignant tumor of the child, recognized for its aggressiveness, its high bone metastatic potential and its tendency to recur. We report a case diagnosed SRCC in a 22-month-old infant with a large right lumbar mass. An observation of Kidney tumor type clear-cell sarcoma, whose diagnosis was placed on a piece of anatomo-pathology, insofar as the imaging remained uncertain as to the Kidney origin of this mass. Apart from the histological aspect, there is currently no criterion for its diagnosis. Its prognosis has been markedly improved by the introduction of new treatment regimens.

Keywords

• Tumor,Kidney,Child,Sarcoma,Clear cells

References

1. 1. Brockert B. Non-Wilms’ renal tumors in children. Urol Clin North Am. 2000;27:463–9.
2. 2. Kidd JM. Exclusion of certain renal neoplasms from the category of Wilms’ tumor. Am J Pathol. 1970;59:16a.
3. 3. Benchekroun A, Ghadouane M, Zannoud M, Alami M, Amhaji R, Faik M. Clear cell sarcoma of the kidney in an adult. A case reports. Ann Urol (Paris). 2002;36:33–5.
4. 4. Glass RBJ, Davidson AJ, Fernbach SK. Clear cell sarcoma of the kidney: CT, Sonographic, and Pathologic correlation. Radiology. 1991;180:715.
5. 5. Argani P, Perlman EJ, Breslow NE, Browning NG, Green DM, D’Angio GJ, et al. Clear cell sarcoma of the kidney. A review of 351 cases from the national Wilms tumor study group pathology center.Am J Surg Pathol. 2000;24:4–18.
6. 6. Bienvenu L, (de) Pinieux G, Dupin P, Choudat L, Vieillefond A. Sarcome à cellules claires du rein chez un jeune adulte. Ann Pathol. 1997;17:396–9.
7. 7. Looi LM, Cheah PL. An immunohistochemical study comparing clear cell sarcoma of the kidney and. Pathology. 1993;25:106–9.
8. 8. Huang CC, Cutcliffe C, Coffin C, Sorensen PH, Beckwith JB, Perlman EJ. Classification of malignant pediatric renal tumors by gene expression. Pediatr Blood Cancer. 2006;46(7):728-38.

9. 9. Green DM, Breslow NE, Beckwith JB, Moksness J, Finklestein JZ, D’Angio GJ. The treatment of children with clear-cell sarcoma of the kidney: A report from the National Wilms’ Tumor Study Group. J Clin Oncol. 1994;12:2132-7.
10. 10. Seibel NL, Li S, Breslow NE, Beckwith JB, Green DM, Haase GM, et al. Effect of duration of treatment on treatment outcome for patients with clear-cell sarcoma of the kidney: a report from the National Wilms’ Tumor Study Group. J Clin Oncol. 2004;22:468-73.