Abstract
Granulosa cell tumor (GCT) of the ovary is a rare tumor representing 2 to 5% of all ovarian neoplasms. It can reproduce or metastasize several years after the initial treatment. In rare cases, CGT can develop on an extra-ovarian site, which is thought to originate from ectopic gonadal tissue along the embryonic genital ridge. We herein present a case of extraovarian granulosa tumor, the clinical and therapeutic aspects, and our approach.
References
- 1. Schumer ST, Cannistra SA. Granulosa cell tumour of the ovary. J Clin Oncol. 2003;21:1180-9.
- 2. Serov SF, Scully RE, Sobin LH: International Histological Classification of Tumours, No. 9. Histological Typing of Ovarian Tumors. Geneva, World Health Organization, 1973
- 3. Kim SH, Park HJ, Linton JA, Shin DH, Yang WI, Chung WY, et al. Extraovarian granulosa cell tumour. Yonsei Med J. 2001;42:360-3.
- 4. Cronjι HS, Niemand I, Bam RH, Woodruff JD. Review of the ¬granulosa-theca cell tumors from the emil Novak ovarian tumor registry. Am J Obstet Gynecol. 1999;180:323-7.
- 5. Reddy DB, Rao DB, Sarojini JS. Extraovarian granulosa cell tumour. J Indian Med Assoc. 1963;41:254-7.
- 6. Sakai Y. Granulosa cell tumor arising in the wall of müllerian cyst of the broad ligament: Report of a case and immunohistochemical study. Arch Gynecol Obstet. 2007;275:145-8.
- 7. Motta PM, Makabe S. Germ cells in the ovarian surface during fetal development in humans. J Submicrosc Cytol 1986;18:271-90.
- 8. Lal A, Bourtsos EP, Nayar R, DeFrias DV. Cytologic features of granulosa cell tumours in fluids and fine needle aspiration specimens. Acta Cytol. 2004;48:315-20.
- 9. Stenwig JT, Hazekamp JT, Beecham JB. Granulosa cell tumours of the ovary: A clinico-pathological study of 118 cases with long term follow-up. Gynecol Oncol. 1979;7:136-52.
- 10. Lappφhn RE, Burger HG, Bouma J, Bangah M, Krans M, de Bruijn HW. Inhibin as a marker for granulosa-cell tumors. N Engl J Med. 1989;321:790-3.
Abstract
Overin granuloza hücreli tümörü (GCT), tüm over neoplazmalarının %2-5'ini oluşturan nadir bir tümördür. Tedaviden birkaç yıl sonra yeniden ortaya çıkabilir veya metastaz yapabilir. Sık olmamakla birlikte, embriyonik genital katlantı üzerindeki ektopik gonadal dokudan köken alarak, ekstra-overyen bir bölgede de görülebilir. Burada bir ekstraovaryen granüloza tümörünü, klinik, terapötik yönleri ve kendi yaklaşımımızla birlikte sunuyoruz.
References
- 1. Schumer ST, Cannistra SA. Granulosa cell tumour of the ovary. J Clin Oncol. 2003;21:1180-9.
- 2. Serov SF, Scully RE, Sobin LH: International Histological Classification of Tumours, No. 9. Histological Typing of Ovarian Tumors. Geneva, World Health Organization, 1973
- 3. Kim SH, Park HJ, Linton JA, Shin DH, Yang WI, Chung WY, et al. Extraovarian granulosa cell tumour. Yonsei Med J. 2001;42:360-3.
- 4. Cronjι HS, Niemand I, Bam RH, Woodruff JD. Review of the ¬granulosa-theca cell tumors from the emil Novak ovarian tumor registry. Am J Obstet Gynecol. 1999;180:323-7.
- 5. Reddy DB, Rao DB, Sarojini JS. Extraovarian granulosa cell tumour. J Indian Med Assoc. 1963;41:254-7.
- 6. Sakai Y. Granulosa cell tumor arising in the wall of müllerian cyst of the broad ligament: Report of a case and immunohistochemical study. Arch Gynecol Obstet. 2007;275:145-8.
- 7. Motta PM, Makabe S. Germ cells in the ovarian surface during fetal development in humans. J Submicrosc Cytol 1986;18:271-90.
- 8. Lal A, Bourtsos EP, Nayar R, DeFrias DV. Cytologic features of granulosa cell tumours in fluids and fine needle aspiration specimens. Acta Cytol. 2004;48:315-20.
- 9. Stenwig JT, Hazekamp JT, Beecham JB. Granulosa cell tumours of the ovary: A clinico-pathological study of 118 cases with long term follow-up. Gynecol Oncol. 1979;7:136-52.
- 10. Lappφhn RE, Burger HG, Bouma J, Bangah M, Krans M, de Bruijn HW. Inhibin as a marker for granulosa-cell tumors. N Engl J Med. 1989;321:790-3.
Details
| Primary Language | English |
|---|---|
| Subjects | Surgery |
| Journal Section | Case report |
| Authors | |
| Publication Date | October 1, 2019 |
| Published in Issue | Year 2019 |