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Giant fibroadenoma of the breast: A case report of a 37-year-old woman during the second trimester of pregnancy

Year 2020, , 613 - 615, 01.07.2020
https://doi.org/10.28982/josam.707606

Abstract

Fibroadenomas are the most common benign breast tumors in young women aged between 20-30 years. Giant fibroadenomas are often larger than 5 cm, weigh more than 500 g or occupy 80% of the breast. They can mimic malignant tumors because they grow rapidly and cause breast deformity. We present a young female patient, in the second trimester of her pregnancy, who had a rapidly growing giant fibroadenoma. Since the mass was suspected of malignancy and caused deformity in the breast, surgical excision was indicated. The operation was performed without complications and the patient was discharged on the second postoperative day. Although the second trimester is suitable for semielective surgeries that cannot be postponed, the timing of the operation is decided by a multidisciplinary team including surgeons, anesthesiologists, obstetricians and perinatologists.

Supporting Institution

Department of General Surgery, Sisli Hamidiye Etfal Medical Practice and Research Center, University of Health Sciences, Istanbul, Turkey.

References

  • 1. Santen RJ, Mansel R. Benign breast disorders. N Engl J Med. 2005;353(3):275–85.
  • 2. Cerrato F, Labow BI. Diagnosis and management of fibroadenomas in the adolescent breast. Semin Plast Surg. 2013;27(1):23–5.
  • 3. Javed A, Jenkins SM, Labow B, Boughey JC, Lemaine V, Neal L et al. Intermediate and Long-Term Outcomes of Fibroadenoma Excision in Adolescent and Young Adult Patients. The Breast Journal. 2019;25(1):91-5.
  • 4. Sosin M, Pulcrano M, Feldman ED, Patel KM, Nahabedian MY, Weissler JM. Giant juvenile fibroadenoma: a systematic review with diagnostic and treatment recommendations. Gland Surg. 2015;4:312–21.
  • 5. Estevão RA, Nazário AC, Baracat EC. Effect of oral contraceptive with and without associated estriol on ultrasound measurements of breast fibroadenoma: randomized clinical trial. Sao Paulo Med J. 2007;125(5):275-80.
  • 6. Bıldırcın FD, Özdemir AZ, Karlı P, Çetinkaya MB. Breast cancer and ovulation induction. J Surg Med. 2019;3(8):612-8.
  • 7. Huang IC, Li PC, Ding DC. Recurrent juvenile fibroadenoma of the breast in an adolescent: A case report. Medicine (Baltimore). 2018;97(20):e10765.
  • 8. Duman L, Gezer NS, Balci P, Altay C, Basara I, Durak MG, et al. Differentiation between Phyllodes Tumors and Fibroadenomas Based on Mammographic Sonographic and MRI Features. Breast Care (Basel). 2016;11:123–7.
  • 9. Shaik AN, Ruterbusch JJ, Abdulfatah E, Shrestha R, Daaboul MHDF, Pardeshi V et al. Breast fibroadenomas are not associated with increased breast cancer risk in an African American contemporary cohort of women with benign breast disease. Breast Cancer Research. 2018;20(1):91.
  • 10. Zhang Y, Kleer CG. Phyllodes tumor of the breast: histopathologic features, differential diagnosis and molecular/genetic updates. Arch Pathol Lab Med. 2016;140(7):665–71.
  • 11. Wolbert T, Leigh ECN, Barry R, Traylor JR, Legenza M. Early stage malignant phyllodes tumor case report. Int J Surg Case Rep. 2018;42:148–53.
  • 12. Zafrakas M, Papasozomenou P, Hatzibougias D. Mixed fibroadenoma and phyllodes breast tumor: Limitations of core needle biopsy. Hippokratia. 2017;21(2):111.
  • 13. Mitus JW, Blecharz P, Jakubowicz J, Reinfuss M, Walasek T, Wysocki W. Phyllodes tumors of the breast. The treatment results for 340 patients from a single cancer centre. Breast. 2019;43:85-90.
  • 14. Langer A, Mohallem M, Berment H, Ferreira F, Gog A, Khalifa D, et al. Breast lumps in pregnant women. Diagn Interv Imaging. 2015;96:1077–87.
  • 15. Heilmann T, Leuschner I, Hilpert F, Kümper C, Strauss A, Mundhenke C, et al. Diagnosis and management of an unilateral giant fibroadenoma of the breast in pregnancy. Arch Gynecol Obstet 2012;285:235-7

Memenin dev fibroadenomu: Gebeliğin ikinci trimesterinde olan 37 yaşında kadın olgu sunumu

Year 2020, , 613 - 615, 01.07.2020
https://doi.org/10.28982/josam.707606

Abstract

Fibroadenomlar, 20-30 yaş arası genç kadınlarda en sık görülen benign meme tümörleridir. Dev fibroadenomlar genellikle 5 cm'den daha büyük boyuta sahip, 500 g'dan daha ağırdır veya memenin % 80'ini kaplarlar. Büyüme hızları ve meme deformitesine neden olabilmeleri nedeniyle malign tümörleri taklit edebilirler. Hamileliğin ikinci trimesterinde ve hızla büyüyen dev fibroadenomu olan genç bir kadın hastayı sunuyoruz. Kitlenin malignite şüphesi olması ve memede deformiteye yol açması nedeniyle cerrahi eksizyon önerildi. Ameliyat komplikasyonsuz gerçekleşti ve hasta ameliyat sonrası ikinci gününde taburcu edildi. İkinci trimester ertelenemeyen semielektif cerrahiler için uygun olsa da, operasyonun zamanlamasına cerrahlar, anestezistler, kadın doğum uzmanları ve perinatologlar dahil olmak üzere multidisipliner bir ekip tarafından karar verilir.

References

  • 1. Santen RJ, Mansel R. Benign breast disorders. N Engl J Med. 2005;353(3):275–85.
  • 2. Cerrato F, Labow BI. Diagnosis and management of fibroadenomas in the adolescent breast. Semin Plast Surg. 2013;27(1):23–5.
  • 3. Javed A, Jenkins SM, Labow B, Boughey JC, Lemaine V, Neal L et al. Intermediate and Long-Term Outcomes of Fibroadenoma Excision in Adolescent and Young Adult Patients. The Breast Journal. 2019;25(1):91-5.
  • 4. Sosin M, Pulcrano M, Feldman ED, Patel KM, Nahabedian MY, Weissler JM. Giant juvenile fibroadenoma: a systematic review with diagnostic and treatment recommendations. Gland Surg. 2015;4:312–21.
  • 5. Estevão RA, Nazário AC, Baracat EC. Effect of oral contraceptive with and without associated estriol on ultrasound measurements of breast fibroadenoma: randomized clinical trial. Sao Paulo Med J. 2007;125(5):275-80.
  • 6. Bıldırcın FD, Özdemir AZ, Karlı P, Çetinkaya MB. Breast cancer and ovulation induction. J Surg Med. 2019;3(8):612-8.
  • 7. Huang IC, Li PC, Ding DC. Recurrent juvenile fibroadenoma of the breast in an adolescent: A case report. Medicine (Baltimore). 2018;97(20):e10765.
  • 8. Duman L, Gezer NS, Balci P, Altay C, Basara I, Durak MG, et al. Differentiation between Phyllodes Tumors and Fibroadenomas Based on Mammographic Sonographic and MRI Features. Breast Care (Basel). 2016;11:123–7.
  • 9. Shaik AN, Ruterbusch JJ, Abdulfatah E, Shrestha R, Daaboul MHDF, Pardeshi V et al. Breast fibroadenomas are not associated with increased breast cancer risk in an African American contemporary cohort of women with benign breast disease. Breast Cancer Research. 2018;20(1):91.
  • 10. Zhang Y, Kleer CG. Phyllodes tumor of the breast: histopathologic features, differential diagnosis and molecular/genetic updates. Arch Pathol Lab Med. 2016;140(7):665–71.
  • 11. Wolbert T, Leigh ECN, Barry R, Traylor JR, Legenza M. Early stage malignant phyllodes tumor case report. Int J Surg Case Rep. 2018;42:148–53.
  • 12. Zafrakas M, Papasozomenou P, Hatzibougias D. Mixed fibroadenoma and phyllodes breast tumor: Limitations of core needle biopsy. Hippokratia. 2017;21(2):111.
  • 13. Mitus JW, Blecharz P, Jakubowicz J, Reinfuss M, Walasek T, Wysocki W. Phyllodes tumors of the breast. The treatment results for 340 patients from a single cancer centre. Breast. 2019;43:85-90.
  • 14. Langer A, Mohallem M, Berment H, Ferreira F, Gog A, Khalifa D, et al. Breast lumps in pregnant women. Diagn Interv Imaging. 2015;96:1077–87.
  • 15. Heilmann T, Leuschner I, Hilpert F, Kümper C, Strauss A, Mundhenke C, et al. Diagnosis and management of an unilateral giant fibroadenoma of the breast in pregnancy. Arch Gynecol Obstet 2012;285:235-7
There are 15 citations in total.

Details

Primary Language English
Subjects Surgery
Journal Section Case report
Authors

Bülent Çitgez 0000-0001-9759-8798

Banu Yiğit 0000-0001-7606-9352

Ramazan Uçak This is me 0000-0002-2999-7495

Sıtkı Gürkan Yetkin This is me 0000-0003-3714-5169

Publication Date July 1, 2020
Published in Issue Year 2020

Cite

APA Çitgez, B., Yiğit, B., Uçak, R., Yetkin, S. G. (2020). Giant fibroadenoma of the breast: A case report of a 37-year-old woman during the second trimester of pregnancy. Journal of Surgery and Medicine, 4(7), 613-615. https://doi.org/10.28982/josam.707606
AMA Çitgez B, Yiğit B, Uçak R, Yetkin SG. Giant fibroadenoma of the breast: A case report of a 37-year-old woman during the second trimester of pregnancy. J Surg Med. July 2020;4(7):613-615. doi:10.28982/josam.707606
Chicago Çitgez, Bülent, Banu Yiğit, Ramazan Uçak, and Sıtkı Gürkan Yetkin. “Giant Fibroadenoma of the Breast: A Case Report of a 37-Year-Old Woman During the Second Trimester of Pregnancy”. Journal of Surgery and Medicine 4, no. 7 (July 2020): 613-15. https://doi.org/10.28982/josam.707606.
EndNote Çitgez B, Yiğit B, Uçak R, Yetkin SG (July 1, 2020) Giant fibroadenoma of the breast: A case report of a 37-year-old woman during the second trimester of pregnancy. Journal of Surgery and Medicine 4 7 613–615.
IEEE B. Çitgez, B. Yiğit, R. Uçak, and S. G. Yetkin, “Giant fibroadenoma of the breast: A case report of a 37-year-old woman during the second trimester of pregnancy”, J Surg Med, vol. 4, no. 7, pp. 613–615, 2020, doi: 10.28982/josam.707606.
ISNAD Çitgez, Bülent et al. “Giant Fibroadenoma of the Breast: A Case Report of a 37-Year-Old Woman During the Second Trimester of Pregnancy”. Journal of Surgery and Medicine 4/7 (July 2020), 613-615. https://doi.org/10.28982/josam.707606.
JAMA Çitgez B, Yiğit B, Uçak R, Yetkin SG. Giant fibroadenoma of the breast: A case report of a 37-year-old woman during the second trimester of pregnancy. J Surg Med. 2020;4:613–615.
MLA Çitgez, Bülent et al. “Giant Fibroadenoma of the Breast: A Case Report of a 37-Year-Old Woman During the Second Trimester of Pregnancy”. Journal of Surgery and Medicine, vol. 4, no. 7, 2020, pp. 613-5, doi:10.28982/josam.707606.
Vancouver Çitgez B, Yiğit B, Uçak R, Yetkin SG. Giant fibroadenoma of the breast: A case report of a 37-year-old woman during the second trimester of pregnancy. J Surg Med. 2020;4(7):613-5.