Akciğer kanserinde tanı ve tedavi gecikme faktörleri

Year 2020, , 720 - 724, 01.09.2020

Fatma İrem Yeşiler , Filiz Çimen Şükran Atikcan

https://doi.org/10.28982/josam.710475

Abstract

Amaç: Akciğer kanseri dünya çapında en önemli mortalite nedenlerinden biridir. Tanı ve tedavi gecikmesi hastalığın prognozunu etkileyen en önemli faktörlerdendir. Amacımız; akciğer kanseri tanısı almış hastalarda tanı ve tedavi gecikmesini etkileyen faktörleri araştırmaktır.
Yöntemler: Ocak 2010 – Ağustos 2011 tarihleri arasında göğüs hastalıkları kliniğinde tanı konulan akciğer kanserli hastaların dosyaları retrospektif olarak incelendi. Hastaların sosyodemografik özellikleri (yaş, cinsiyet, meslek ve eğitim düzeyi), semptom tipi, başka malignite varlığı, lezyonun radyolojik lokalizasyonu, tanı yöntemi, histolojik tip, endobronşiyal lezyon varlığı, akciğer kanseri evresi, başvuru, tanı ve tedavi arasındaki sürelerin uzunluğu kaydedildi. Çalışma, retrospektif kohort çalışmasıdır.
Bulgular: Olguların 107’ si (%87,7) erkek ve 15’ i (%12,3) kadındı. 89 olgu (%73) 70 yaş altındaydı. 98 olgu küçük hücre dışı akciğer kanseri (KHDAK) iken 24 olgu küçük hücreli akciğer kanseri (KHAK) idi. Semptomlarının başlangıcından hastaneye başvurusuna (SB), semptomların başlangıcından patolojik tanıya (SP), tedavi başlangıcına (ST), başvurudan patolojik tanıya (BP), başvurudan tedavi başlangıcına (BT) kadar geçen ortalama süre sırayla 30, 60, 75,5, 14, 33 gün olarak bulundu. Öğrenim düzeyi ile SP, BP, BT süreleri (sırasıyla P=0,017, P=0,011 ve P=0,006); sosyal güvence ile SB, SP, ST, SR süreleri arasında istatistiksel olarak anlamlı farklılık saptandı (P<0,05 tümü için). KHAK’ de BT süresi KHDAK’ ye göre daha kısa olduğu saptandı
Sonuç: Akciğer kanserinde erken tanı konulması oldukça önemlidir. Bu nedenle tanı ve tedaviyi geciktirecek faktörlerin saptanması, olası nedenlerinin ve çözümlerinin araştırılması gerekmektedir.

Keywords

Akciğer kanseri, Gecikmeler, Tanı, Tedavi

Supporting Institution

yok

Project Number

Ethics committee approval was received from Ataturk Chest Diseases and Chest Surgery Training and Research Hospital regional ethical committee in April 2012.

Factors affecting delay in diagnosis and treatment of lung cancer

Abstract

Aim: Lung cancer (LC) is one of the most prominant causes of mortality in the world. Delays in diagnosis and treatment gravely affect the prognosis of the disease. Our aim is to investigate the factors that affect delay in diagnosis and treatment in patients with LC.
Methods: In this retrospective cohort study, LC patients who were diagnosed in the pulmonary diseases clinic between January 2010 and August 2011 were retrospectively evaluated from patient files. The sociodemographic characteristics of the patients (age, gender, occupation and educational level), symptom type, presence of other malignancies, radiological location of the lesion, diagnostic method, histological type, presence of endobronchial lesion, stage of LC, length of times between admission, diagnosis and treatment were noted.
Results: One hundred seven (87.7%) patients were male and 15 patients (12.3%) were female. Eighty-nine patients (73%) were under the age of 70 years. Ninety-eight patients were diagnosed with non-small cell (NSCLC) and 24 patients, with small cell lung cancer (SCLC). The mean duration from symptom onset to admission to the hospital (SA), from symptom onset to pathological diagnosis (SP), from symptom onset to initiating treatment (ST), from admission to the hospital until pathological diagnosis (AP), from admission to the hospital until initiating treatment (AT) were 30, 60, 75,5, 14, 33 days, respectively. There were statistically significant differences between SP, AP, AT periods (P=0.017, P=0.011 and P=0.006 respectively) with regards to education levels, and between SA, SP, ST, and from symptom onset to performing an initial radiological examination (SR) periods in terms of social security institution (P<0.05 for all). AT time of patients with SCLC was shorter than that of patients with NSCLC.
Conclusion: Early diagnosis of LC is particularly important. Therefore, determination of factors affecting the delay in diagnosis and treatment of LC, probable causes, and solutions should be investigated.

Keywords

Lung cancer, delays, diagnosis, treatment

Project Number

Ethics committee approval was received from Ataturk Chest Diseases and Chest Surgery Training and Research Hospital regional ethical committee in April 2012.

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