The association between red cell distribution width to total calcium ratio and syntax score in patients with acute coronary syndrome

Abstract

Aim: The relationship of both red blood cell distribution width (RDW) and Syntax risk score with prognosis and mortality in patients with acute coronary syndrome (ACS) has been shown. Besides, there is insufficient information about the use of red cell distribution width to total serum calcium (RDW-to-TSC) ratio in patients with ACS. We aimed to research the relationship between RDW-to-TSC and Syntax risk scores in our study. Methods: For our retrospective cohort study, 270 patients hospitalized in the cardiology intensive care unit with the diagnosis of myocardial infarction between January 2019 and December 2019 were screened. A total of 115 patients who were eligible were included in the study. The patients were classified into two groups: 58 had NSTE-ACS and 57 had STEMI. The included age range was 18-80 years. RDW-to-TSC was calculated as the ratio of red cell distribution width to total serum calcium count. By using Pearson's correlation analysis, the relationship between RDW-TAF ratio and Syntax score was obtained. Results: Among 115 patients, there were 50 males (43.5%), and 65 females (56.5%). The mean age was 58.09 (9.55) years. There were more hypertensive patients in the NSTE-ACS group (P=0.003). There was no statistically significant difference in RDW-to-TSC ratio between the two groups (P=0.809). The correlation of RDW and RDW / TSC ratio with syntax score were statistically significant (P<0.001). Conclusions: RDW-to-TSC ratio is a simple, cost-effective, and readily available test in all health centers. This may be used as a risk calculation tool like the Syntax score for patients with ACS.

Keywords

• Acute coronary syndrome
• serum calcium
• red cell distribution width

Akut koroner sendromlu hastalarda kırmızı hücre dağılım genişliğinin total kalsiyuma oranının syntax skoru ile ilişkisi

Öz

Amaç: Eritrosit dağılım genişliğinin (RDW) ve Syntax risk skorunun akut koroner sendrom (AKS) tanılı hastalarda prognoz ve mortalite ile ilişkileri gösterilmiştir. Bununla birlikte eritrosit dağılım genişliğinin serum kalsiyuma oranı (RDW/TSK) ile ilgili yeterli bilgiler yoktur. Bu çalışmanın amacı RDW-TSK oranının Syntax risk skoru ile ilişkisini araştırmayı hedefledik. Yöntemler: Çalışmamız retrospektif kohort çalışması olup, Ocak 2019-Aralık 2019 tarihleri arasında kardiyoloji yoğun bakım ünitesinde miyokard enfarktüsü tanısı ile yatışı olan 270 hasta tarandı. Dışlama kriterlerinden sonra uygun olan 115 hasta çalışmaya alındı. Bu alınan hastaların 58 tanesi NSTE-AKS'li ve 57 tanesi STEMI olarak iki gruba sınıflandırıldı. Çalışmaya 18-80 yaş arası hastalar dahil edildi. RDW-TSK, eritrosit dağılım genişliğinin toplam serum kalsiyum sayısına oranı olarak hesaplandı. Pearson korelasyon analizi kullanılarak RDW-TSK oranı ile Syntax skoru arasındaki ilişki elde edildi. Bulgular: 115 hastanın 50 tanesi erkek (%43,5), 65 tanesi kadın (%56,5) ve ortalama yaşları 58,09 (9,55) yıldı. NSTE-AKS grubunda daha fazla hipertansiyon hastası vardı (P=0,003). Gruplar arasında RDW / TSK oranında istatistiksel olarak anlamlı fark yoktu (P=0,809). RDW ve RDW / TSK oranı korelasyonu syntax skoru ile istatistiksel olarak anlamlı idi (P<0,001). Sonuç: RDW / TSK oranı, tüm sağlık merkezlerinde basit, uygun maliyetli ve kolay ulaşılabilir bir testtir. Bununla birlikte AKS hastalarında Syntax skoru gibi risk hesaplama aracı olabilir.

Anahtar Kelimeler

• Akut koroner sendrom
• Serum kalsiyum
• Eritrosit dağılım dağıtım genişliği

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