Helicobacter pylori incidence of patients with gastritis in endoscopic biopsies

Abstract

Aim: H. pylori is the most common permanent bacterial infection worldwide and an important health problem in terms of the diseases it causes. The aim of this study was to determine H. pylori incidence according to age and gender in biopsy materials of patients who were diagnosed with gastritis.
Methods: This was a cross-sectional study which examined the endoscopic and pathological reports of 1240 patients who were diagnosed with gastritis between June 2014 and October 2019 and underwent biopsy from the antrum. The incidence of H. pylori infection was evaluated according to age and gender. Based on the Sydney classification, the patients were scored as none (-), low (+), medium (++) and high (+++) in the pathological records. Patients were divided into 5 age groups: 18-34, 35-44, 45-64, 65-74 and ≥75 years.
Results: A total of 1240 patients, 664 (53.5%) females and 576 (465%) males were included in the study. The mean age of the patients was 49.9 (16.2). A total of 422 (34.0%) patients were H. pylori (+), while 818 (66.0%) were H. pylori (-). H. pylori density was low in 123 (29.1%) patients, medium in 207 (49.1%) patients, and high in 92 (21.8%) patients. There was no difference in terms of H. pylori positivity with regards to age and gender (P=0.296, P=0,812, respectively). The number of H. pylori (+) and (-) patients in the groups were as follows: Group 1: 71 (16.8%) vs. 160 (19.6%), Group 2: 125 (29.6%) vs. 186 (22.7%), Group 3: 134 (31.8%) vs. 281 (34.4%), Group 4: 60 (14.2%) vs. 120 (14.7%) and Group 5: 32 (7.6%) vs. 71 (8.7%). H. pylori positivity rates were as 30.7%, 40.2%, 32.3%, 33.3% and 31.1% for groups 1, 2, 3, 4 and 5, respectively. Although the Group 2 (35-44 years) had the highest rate, it was not statistically significant (P=0.117).
Conclusion: In our study, the incidence of H. pylori was 34%, and this rate is pleasing in terms of decreasing H. pylori incidence in our country compared to previous studies

Keywords

• H. pylori,Incidence,Age,Gender

Endoskopik biyopsilerde gastrit saptanan hastalarda helikobakter pylori sıklığı

Öz

Amaç: H. pylori dünya çapında en sık görülen kalıcı bakteriyel enfeksiyondur ve neden olduğu hastalıklar açısından önemli bir sağlık sorunudur. Bu çalışmanın amacı, endoskopik olarak gastrit tanısı alan hastaların biyopsi materyallerinde yaş ve cinsiyete göre H. pylori insidansını belirlemektir.
Yöntemler: Bu çalışma Haziran 2014-Ekim 2019 tarihleri arasında gastrit tanısı alan ve antrumdan biyopsi yapılan 1240 hastanın endoskopik ve patolojik raporlarını inceleyen kesitsel bir çalışmadır. Sydney sınıflamasına göre, hastalar patolojik kayıtlarda yok (-), düşük (+), orta (++) ve yüksek (+++) olarak skorlandı. Hastalar ; 18-34, 35-44, 45-64, 65-74 ve ≥75 olmak üzere 5 farklı yaş grubuna ayrıldı.
Bulgular: Çalışmaya 664 (%53,5) kadın ve 576 (%46,5) erkek olmak üzere toplam 1240 hasta dahil edildi. Hastaların ortalama yaşı 49,9 (16,2) idi. H. pylori (+) olanların sayısı 422 (%34,0), H. pylori (-) olanların sayısı ise 818 (%66,0) di. H. pylori yoğunluğuna göre değerlendirildiğinde 123 (%29,1) hastada düşük, 207 (%49,1) hastada orta ve 92 (%21,8) hastada yüksekti. Yaş ve cinsiyetler arasında H. pylori pozitifliği açısından herhangi bir fark yoktu (Sırasıyla P=0,296, P=0,812). Gruplardaki H. pylori (+) ve (-) hasta sayısı şöyleydi: Grup 1: 71 (%16,8) - 160 (%19,6), Grup 2: 125 (%29,6) - 186 (%22,7), Grup 3: 134 (%31,8) - 281 (%34,4), Grup 4: 60 (%14,2) - 120 (%14,7) ve Grup 5: 32 (%7,6) - 71 (%8,7). 1,2,3,4 ve 5. gruplardaki H. pylori pozitiflik oranları sırasıyla %30,7, %40,2, %32,3, %33,3 ve %31,1 idi. En yüksek oran grup 2'de (35-44 yaş) saptanmış olmasına rağmen, bu istatistiksel olarak anlamlı değildi (P=0,117).
Sonuç: Çalışmamızda, H. pylori insidansı %34 olarak saptanmıştır ve bu oran daha önceki çalışmalarla kıyaslandığında, ülkemizde H. pylori insidansının azalması açısından memnuniyet vericidir.

Anahtar Kelimeler

• H. pylori,Sıklık,Yaş,Cinsiyet

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