May Covid-19 cause intracerebral hemorrhage in patients with cavernous malformation?

Abstract

Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has become a global health threat. COVID-19 often involves the respiratory tract, however, it is also associated with several neurological conditions (seizures, convulsions, changes in consciousness, encephalitis, cerebral hemorrhage, and cerebral thrombosis). Cavernous malformations (CMs) are vascular lesions that occur in the central nervous system and the body. Symptomatic CMs most manifest through headaches, seizures, hemorrhage, or focal neurological deficits. The co-occurrence of COVID-19 and cavernous hemangioma hemorrhage has not been reported in the literature. The association between COVID-19 and intracerebral hemorrhage remains controversial. However, a relationship with COVID-19 infection in patients with intracerebral hemorrhage should always be considered during this pandemic. The case of a 37-year-old female patient is reported here. The patient presented to the emergency room with a headache that persisted for 2 days along with cavernous hemangioma hemorrhage and tested positive for COVID-19.

Keywords

• COVID-19
• Haemangioma
• Cavernous

Covid-19, kavernöz malformasyonlu hastalarda intraserebral kanama'ya neden olabilir mi?

Öz

SARS-CoV-2 virüsünün neden olduğu Coronavirus hastalığı 2019 (COVID-19), küresel bir sağlık tehdidi haline geldi. COVID-19 genellikle solunum yolunu tutar; bununla birlikte çeşitli nörolojik durumlarla (nöbetler, konvülsiyonlar, bilinç değişiklikleri, ensefalit, serebral hemoraji ve serebral tromboz) ilişkili olduğu da bulunmuştur. Kavernöz malformasyonlar (KM), merkezi sinir sisteminde ve vücutta meydana gelen vasküler lezyonlardır. Semptomatik KM'ler en yaygın olarak baş ağrısı, nöbetler, kanama veya fokal nörolojik defisitlerle kendini gösterir. Literatürde COVID-19 ile kavernöz hemanjiyom kanamasının birlikte görülmesi bildirilmemiştir. COVID-19 ile intraserebral hemoraji arasındaki ilişki tartışmalıdır. Bununla birlikte, intraserebral hemorajili hastalarda COVID-19 enfeksiyonu ile bir ilişki bu pandemi sırasında her zaman dikkate alınmalıdır. 37 yaşında bir kadın hastanın vakası burada bildirilmektedir. Hasta kavernöz hemanjiyom kanaması ile birlikte 2 gün süren baş ağrısı ile acil servise başvurdu ve ayrıca COVID-19 testi pozitif çıktı.

Anahtar Kelimeler

• COVID-19
• Hemanjiom
• Kavernöz

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