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Obsesif-kompülsif bozukluk hastalarında anksiyete duyarlılığı ve intihar düşüncesi arasındaki ilişki: Kontrollü çalışma

Year 2020, , 1052 - 1056, 01.11.2020

Rukiye Ay , Oğuzhan Kılınçel

https://doi.org/10.28982/josam.805189

Abstract

Amaç: Obsesif kompulsif bozukluk (OKB) intihar riski ile ilişkilidir, ancak OKB'de intihar sıklığı ve yükü konusunda hala bir tartışma vardır. Bu çalışmanın amacı obsesif-kompülsif bozukluk (OKB) hastalarındaki anksiyete duyarlılığı ile intihar düşüncesi arasındaki ilişkiyi saptamaktır.
Yöntemler: Bu kontrollü çalışma 36 OKB hastası ve 36 sağlıklı kontrolü içermekteydi. Tüm olgular Beck Depresyon Skalası (BDS), Beck Anksiyete Skalası (BAS), Yale-Brown Obsesyon Kompülsiyon Ölçeği (YBOKÖ), Anksiyete-Sensivite İndeksi-3 (ASI-3) ve İntihar Olasılığı Ölçeği (İOÖ) ile değerlendirildi. Demografik veriler her hastadan kayıt edildi.
Bulgular: Yetmiş iki olgu çalışmaya dahil edildi. Ortalama yaş 31,89 (9,69) idi. Gruplar arasında intihar girişim hikâyesi, ailede intihar girişim hikâyesi ve herhangi bir kronik hastalık varlığı açısından fark yoktu. BDS, BAÖ ve ASI-3 skorları hasta grubunda kontrol grubuna göre anlamlı olarak daha yüksekti (P>0,05). BDS, BAÖ, ASI-3 ve İOÖ umutsuzluk, intihar düşüncesi, düşmanlık ve total skorları arasında anlamlı korelasyonlar saptandı (P>0,05).
Sonuç: Bu çalışma depresyon ve anksiyete durumunun OKB hastalarında intihar riski için önemli olduğunu saptamıştır. Bu nedenle OKB tanısı alan hastaların intihar düşüncesi açısından her zaman değerlendirilmesi önerilir.

Keywords

Obsesif-kompülsif bozukluk Anksiyete Depresyon İntihar

References

  • 1. Nagy NE, El-Serafi DM, Elrassas HH, Abdeen MS, Mohamed DA. Impulsivity, hostility and suicidality in patients diagnosed with obsessive compulsive disorder. Int J Psychiatry Clin Pract. 2020;24(3):284-92.
  • 2. Coryell W. Obsessive-compulsive disorder and primary unipolar depression. Comparisons of background, family history, course, and mortality. J Nerv Ment Dis. 1981;169(4):220-4.
  • 3. Khan A, Leventhal RM, Khan S, Brown WA. Suicide risk in patients with anxiety disorders: a meta-analysis of the FDA database. J Affect Disord. 2002;68(2-3):183-90.
  • 4. Beck AT, Weissman A, Lester D, Trexler L. The measurement of pessimism: the hopelessness scale. J Consult Clin Psychol. 1974;42(6):861-5.
  • 5. Joiner TE Jr, Steer RA, Brown G, Beck AT, Pettit JW, Rudd MD. Worst-point suicidal plans: a dimension of suicidality predictive of past suicide attempts and eventual death by suicide. Behav Res Ther. 2003;41(12):1469-80.
  • 6. Angelakis I, Gooding P, Tarrier N, Panagioti M. Suicidality in obsessive compulsive disorder (OCD): a systematic review and meta-analysis. Clin Psychol Rev. 2015;39:1-15.
  • 7. Albert U, De Ronchi D, Maina G, Pompili M. Suicide Risk in Obsessive-Compulsive Disorder and Exploration of Risk Factors: A Systematic Review. Curr Neuropharmacol. 2019;17(8):681-96.
  • 8. Stanley IH, Boffa JW, Rogers ML, et al. Anxiety sensitivity and suicidal ideation/suicide risk: A meta-analysis. J Consult Clin Psychol. 2018;86(11):946-60.
  • 9. Fawcett J, Scheftner WA, Fogg L, Clark DC, Young MA, Hedeker D, et al. Time-related predictors of suicide in major affective disorder. Am J Psychiatry. 1990;147(9):1189-94.
  • 10. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), clinician version, user's guide, Washington, DC: American Psychiatric Association; 1997.
  • 11. Kundakçi T, Sar V, Kiziltan E, Yargiç IL, Tutkun H. Reliability and validity of the Turkish version of the Structured Clinical Interview for DSM-IV Dissociative Disorders (SCID-D): a preliminary study. J Trauma Dissociation. 2014;15(1):24-34.
  • 12. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry. 1961;4:561-71.
  • 13. Hisli N. Reliability and validity of Beck Depression Inventory among university students. Turk Psikoloji Dergisi 1989;7(23):3-13.
  • 14. Beck AT, Epstein N, Brown G, Steer RA. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol. 1988;56:893–7.
  • 15. Ulusoy M, Şahin N, Erkmen H. Turkish version of Beck Anxiety inventory: Psychometric Properties. J Cogn Psychother 1998;12(2):163-72.
  • 16. Taylor S, Zvolensky MJ, Cox BJ, Deacon B, Heimberg RG, Ledley DR, et al. Robust dimensions of anxiety sensitivity: development and initial validation of the Anxiety Sensitivity Index-3. Psychol Assess. 2007;19:176-88.
  • 17. Mantar A, Yemez B, Alkın T. Anksiyete Duyarliliği Indeksi-3'ün Türkçe Formunun Geçerlik ve Güvenilirlik Calışması [The validity and reliability of the Turkish version of the anxiety sensitivity index-3]. Turk Psikiyatri Derg. 2010;21(3):225-34.
  • 18. Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry. 1989 Nov;46(11):1006-11.
  • 19. Karamustafalıoğlu OK, Ucışık AM, Ulusoy M, Erkmen H. Yale-Brown Obsesyon-Kompülsiyon Derecelendirme Ölçeğinin Geçerlilik ve Güvenilirlik Çalışması. 29. Ulusal Psikiyatri Kongresi Program ve Bildiri Özetleri Kitabı, Bursa Savaş Ofset;1993. p. 86.
  • 20. Cull J, Gill W. Suicide probability scale. Los Angeles, CA: WPS, 1982.
  • 21. Atlı Z, Eskin M, Dereboy C. The Validity and the Reliability of Suicide Probability Scale (SPS) in Clinical Sample. J Clin Psy. 2009;12(3):111-124.
  • 22. Khosravani V, Sharifi Bastan F, Samimi Ardestani M, Jamaati Ardakani R. Early maladaptive schemas and suicidal risk in an Iranian sample of patients with obsessive-compulsive disorder. Psychiatry Res. 2017;255:441-8.
  • 23. Albert U, Speciani M, De Ronchi D, Atti AR, Maina G, Bélteczky Z, et al. Factors associated with increased suicide risk in obsessive-compulsive disorder. J Psychopathol. 2018;24:154–63.
  • 24. Balci V, Sevincok L. Suicidal ideation in patients with obsessive-compulsive disorder. Psychiatry Res. 2010;175(1-2):104-8.
  • 25. Bolton JM, Cox BJ, Afifi TO, Enns MW, Bienvenu OJ, Sareen J. Anxiety Disorders and Risk for Suicide Attempts: Findings from the Baltimore Epidemiologic Catchment Area Follow-up Study. Depression and Anxiety. 2008;25:477–81.
  • 26. Raines AM, Short NA, Allan NP, Oglesby ME, Schmidt NB. Examination of a brief anxiety sensitivity cognitive concerns intervention on suicidality among individuals with obsessive-compulsive symptoms. Contemp Clin Trials. 2015;45:191-5.
  • 27. Maina G, Albert U, Rigardetto S, Tiezzi M.N, Bogetto F. Suicidio e disturbo ossessivo-compulsivo. Giornale Italiano di Psicopatologia. 2006;12:31–7.
  • 28. Diaconu G, Turecki G. Obsessive-compulsive personality disorder and suicidal behavior: evidence for a positive association in a sample of depressed patients. J Clin Psychiatry. 2009;70(11):1551-6.
  • 29. Torres AR, Ramos-Cerqueira AT, Ferrão YA, Fontenelle LF, do Rosário MC, Miguel EC. Suicidality in obsessive-compulsive disorder: prevalence and relation to symptom dimensions and comorbid conditions. J Clin Psychiatry. 2011;72(1):17-26.
  • 30. Kamath P, Reddy YC, Kandavel T. Suicidal behavior in obsessive-compulsive disorder. J Clin Psychiatry. 2007;68:1741–50.
  • 31. Kılınçel O, Kılınçel Ş, Gündüz C, Cangür Ş, Akkaya C. Klozapinin Hızlı Döngülü Bipolar Afektif Bozuklukta Duygudurum Düzenleyicisi Olarak Rolü. Turk Psikiyatri Dergisi 2019;30(4):268-71.

Association between suicide idea and anxiety sensitivity in obsessive-compulsive disorder: A controlled study

Year 2020, , 1052 - 1056, 01.11.2020

Rukiye Ay , Oğuzhan Kılınçel

https://doi.org/10.28982/josam.805189

Abstract

Aim: Obsessive-compulsive disorder (OCD) is associated with suicide risk, but controversy remains about the frequency and burden of suicidality in OCD. This study aimed to identify the relationship between anxiety sensitivity and suicidal idea in patients with OCD.
Methods: This controlled study included 36 OCD patients and 36 healthy controls. All individuals were evaluated with Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Anxiety Sensitivity Index-3 (ASI-3) and Suicide Probability Scale (SPS). Demographic data were obtained from each patient.
Results: Seventy-two individuals with a mean age of 31.89 (9.69) years were included in this study. No significant differences were found between the groups with regards to individual and family histories of suicide attempt and the presence of other chronic diseases (P>0.05 for each). The patients had significantly higher BDI, BAI and ASI-3 scores than the controls (P>0.05 for each). There were significant correlations between BDI, BAI, ASI-3 and SPS desperation, suicide ideation scores, hostility scores and total scores (P<0.05 for each).
Conclusion: The present study revealed that depression and anxiety status are important for suicide risk in OCD patients. Therefore, it is recommended to always evaluate the risk of suicide in these patients.

Keywords

Obsessive-Compulsive Disorder Anxiety Suicidality Depression

References

  • 1. Nagy NE, El-Serafi DM, Elrassas HH, Abdeen MS, Mohamed DA. Impulsivity, hostility and suicidality in patients diagnosed with obsessive compulsive disorder. Int J Psychiatry Clin Pract. 2020;24(3):284-92.
  • 2. Coryell W. Obsessive-compulsive disorder and primary unipolar depression. Comparisons of background, family history, course, and mortality. J Nerv Ment Dis. 1981;169(4):220-4.
  • 3. Khan A, Leventhal RM, Khan S, Brown WA. Suicide risk in patients with anxiety disorders: a meta-analysis of the FDA database. J Affect Disord. 2002;68(2-3):183-90.
  • 4. Beck AT, Weissman A, Lester D, Trexler L. The measurement of pessimism: the hopelessness scale. J Consult Clin Psychol. 1974;42(6):861-5.
  • 5. Joiner TE Jr, Steer RA, Brown G, Beck AT, Pettit JW, Rudd MD. Worst-point suicidal plans: a dimension of suicidality predictive of past suicide attempts and eventual death by suicide. Behav Res Ther. 2003;41(12):1469-80.
  • 6. Angelakis I, Gooding P, Tarrier N, Panagioti M. Suicidality in obsessive compulsive disorder (OCD): a systematic review and meta-analysis. Clin Psychol Rev. 2015;39:1-15.
  • 7. Albert U, De Ronchi D, Maina G, Pompili M. Suicide Risk in Obsessive-Compulsive Disorder and Exploration of Risk Factors: A Systematic Review. Curr Neuropharmacol. 2019;17(8):681-96.
  • 8. Stanley IH, Boffa JW, Rogers ML, et al. Anxiety sensitivity and suicidal ideation/suicide risk: A meta-analysis. J Consult Clin Psychol. 2018;86(11):946-60.
  • 9. Fawcett J, Scheftner WA, Fogg L, Clark DC, Young MA, Hedeker D, et al. Time-related predictors of suicide in major affective disorder. Am J Psychiatry. 1990;147(9):1189-94.
  • 10. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), clinician version, user's guide, Washington, DC: American Psychiatric Association; 1997.
  • 11. Kundakçi T, Sar V, Kiziltan E, Yargiç IL, Tutkun H. Reliability and validity of the Turkish version of the Structured Clinical Interview for DSM-IV Dissociative Disorders (SCID-D): a preliminary study. J Trauma Dissociation. 2014;15(1):24-34.
  • 12. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry. 1961;4:561-71.
  • 13. Hisli N. Reliability and validity of Beck Depression Inventory among university students. Turk Psikoloji Dergisi 1989;7(23):3-13.
  • 14. Beck AT, Epstein N, Brown G, Steer RA. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol. 1988;56:893–7.
  • 15. Ulusoy M, Şahin N, Erkmen H. Turkish version of Beck Anxiety inventory: Psychometric Properties. J Cogn Psychother 1998;12(2):163-72.
  • 16. Taylor S, Zvolensky MJ, Cox BJ, Deacon B, Heimberg RG, Ledley DR, et al. Robust dimensions of anxiety sensitivity: development and initial validation of the Anxiety Sensitivity Index-3. Psychol Assess. 2007;19:176-88.
  • 17. Mantar A, Yemez B, Alkın T. Anksiyete Duyarliliği Indeksi-3'ün Türkçe Formunun Geçerlik ve Güvenilirlik Calışması [The validity and reliability of the Turkish version of the anxiety sensitivity index-3]. Turk Psikiyatri Derg. 2010;21(3):225-34.
  • 18. Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry. 1989 Nov;46(11):1006-11.
  • 19. Karamustafalıoğlu OK, Ucışık AM, Ulusoy M, Erkmen H. Yale-Brown Obsesyon-Kompülsiyon Derecelendirme Ölçeğinin Geçerlilik ve Güvenilirlik Çalışması. 29. Ulusal Psikiyatri Kongresi Program ve Bildiri Özetleri Kitabı, Bursa Savaş Ofset;1993. p. 86.
  • 20. Cull J, Gill W. Suicide probability scale. Los Angeles, CA: WPS, 1982.
  • 21. Atlı Z, Eskin M, Dereboy C. The Validity and the Reliability of Suicide Probability Scale (SPS) in Clinical Sample. J Clin Psy. 2009;12(3):111-124.
  • 22. Khosravani V, Sharifi Bastan F, Samimi Ardestani M, Jamaati Ardakani R. Early maladaptive schemas and suicidal risk in an Iranian sample of patients with obsessive-compulsive disorder. Psychiatry Res. 2017;255:441-8.
  • 23. Albert U, Speciani M, De Ronchi D, Atti AR, Maina G, Bélteczky Z, et al. Factors associated with increased suicide risk in obsessive-compulsive disorder. J Psychopathol. 2018;24:154–63.
  • 24. Balci V, Sevincok L. Suicidal ideation in patients with obsessive-compulsive disorder. Psychiatry Res. 2010;175(1-2):104-8.
  • 25. Bolton JM, Cox BJ, Afifi TO, Enns MW, Bienvenu OJ, Sareen J. Anxiety Disorders and Risk for Suicide Attempts: Findings from the Baltimore Epidemiologic Catchment Area Follow-up Study. Depression and Anxiety. 2008;25:477–81.
  • 26. Raines AM, Short NA, Allan NP, Oglesby ME, Schmidt NB. Examination of a brief anxiety sensitivity cognitive concerns intervention on suicidality among individuals with obsessive-compulsive symptoms. Contemp Clin Trials. 2015;45:191-5.
  • 27. Maina G, Albert U, Rigardetto S, Tiezzi M.N, Bogetto F. Suicidio e disturbo ossessivo-compulsivo. Giornale Italiano di Psicopatologia. 2006;12:31–7.
  • 28. Diaconu G, Turecki G. Obsessive-compulsive personality disorder and suicidal behavior: evidence for a positive association in a sample of depressed patients. J Clin Psychiatry. 2009;70(11):1551-6.
  • 29. Torres AR, Ramos-Cerqueira AT, Ferrão YA, Fontenelle LF, do Rosário MC, Miguel EC. Suicidality in obsessive-compulsive disorder: prevalence and relation to symptom dimensions and comorbid conditions. J Clin Psychiatry. 2011;72(1):17-26.
  • 30. Kamath P, Reddy YC, Kandavel T. Suicidal behavior in obsessive-compulsive disorder. J Clin Psychiatry. 2007;68:1741–50.
  • 31. Kılınçel O, Kılınçel Ş, Gündüz C, Cangür Ş, Akkaya C. Klozapinin Hızlı Döngülü Bipolar Afektif Bozuklukta Duygudurum Düzenleyicisi Olarak Rolü. Turk Psikiyatri Dergisi 2019;30(4):268-71.
There are 31 citations in total.

Details

Primary Language English
Subjects Psychiatry
Journal Section Research article
Authors

Rukiye Ay 0000-0003-2854-5128

Oğuzhan Kılınçel 0000-0003-2988-4631

Publication Date November 1, 2020
Published in Issue Year 2020

Cite

APA Ay, R., & Kılınçel, O. (2020). Association between suicide idea and anxiety sensitivity in obsessive-compulsive disorder: A controlled study. Journal of Surgery and Medicine, 4(11), 1052-1056. https://doi.org/10.28982/josam.805189
AMA Ay R, Kılınçel O. Association between suicide idea and anxiety sensitivity in obsessive-compulsive disorder: A controlled study. J Surg Med. November 2020;4(11):1052-1056. doi:10.28982/josam.805189
Chicago Ay, Rukiye, and Oğuzhan Kılınçel. “Association Between Suicide Idea and Anxiety Sensitivity in Obsessive-Compulsive Disorder: A Controlled Study”. Journal of Surgery and Medicine 4, no. 11 (November 2020): 1052-56. https://doi.org/10.28982/josam.805189.
EndNote Ay R, Kılınçel O (November 1, 2020) Association between suicide idea and anxiety sensitivity in obsessive-compulsive disorder: A controlled study. Journal of Surgery and Medicine 4 11 1052–1056.
IEEE R. Ay and O. Kılınçel, “Association between suicide idea and anxiety sensitivity in obsessive-compulsive disorder: A controlled study”, J Surg Med, vol. 4, no. 11, pp. 1052–1056, 2020, doi: 10.28982/josam.805189.
ISNAD Ay, Rukiye - Kılınçel, Oğuzhan. “Association Between Suicide Idea and Anxiety Sensitivity in Obsessive-Compulsive Disorder: A Controlled Study”. Journal of Surgery and Medicine 4/11 (November 2020), 1052-1056. https://doi.org/10.28982/josam.805189.
JAMA Ay R, Kılınçel O. Association between suicide idea and anxiety sensitivity in obsessive-compulsive disorder: A controlled study. J Surg Med. 2020;4:1052–1056.
MLA Ay, Rukiye and Oğuzhan Kılınçel. “Association Between Suicide Idea and Anxiety Sensitivity in Obsessive-Compulsive Disorder: A Controlled Study”. Journal of Surgery and Medicine, vol. 4, no. 11, 2020, pp. 1052-6, doi:10.28982/josam.805189.
Vancouver Ay R, Kılınçel O. Association between suicide idea and anxiety sensitivity in obsessive-compulsive disorder: A controlled study. J Surg Med. 2020;4(11):1052-6.