The effect of uterine and spiral artery Doppler velocimetry in predicting miscarriage in threatened miscarriage patients

Abstract

Background/Aim: Doppler sonography was used to investigate the effect of abnormal placentation on early and late pregnancy complications with conflicting results on changes in uterine blood flow and spiral arteries in early pregnancy. This study aimed to compare the uterine and spiral artery Doppler findings between healthy pregnant women and patients with threatened miscarriage. Methods: In this prospective case-control study, the uterine and spiral artery Doppler findings of 60 patients with threatened miscarriage between 12-20 weeks of gestation were compared with those of 60 healthy pregnant women at similar gestational weeks. Resistance index, spiral artery pulsatility index, systolic/diastolic ratio, and uterine artery Doppler values were evaluated. Results: The patients in the threatened miscarriage group had a higher mean age than those in the control group (P<0.001). No significant difference was found between the groups in terms of uterine artery and spiral artery resistance index, systolic/diastolic ratio, and pulsatility index values (P>0.05 for each). Conclusions: Our results showed that there was no significant difference between the indexes of spiral and uterine artery in Doppler ultrasonography. Further studies are needed to evaluate uterine vascular bed alterations to predict the threatened miscarriage prognosis in the first trimester.

Keywords

• Resistance index
• Pulsatility index
• Spiral artery Doppler
• Threatened miscarriage
• Uterine artery Doppler

Uterin ve spiral arter doppler velosimetrisinin abortus imminens hastalarında abortusu öngörmedeki etkisi

Öz

Giriş: Uterin ve spiral arter doppler bulgularının sağlıklı gebeler ve abortus imminens tanılı hastalar arasında karşılaştırılması. Yöntemler: Çalışma prospektif vaka-kontrol çalışması olarak planlandı. 12-20 hafta arası gebeliği olan abortus imminens tanılı hastalar ve sağlıklı gebeler arasında uterin ve spiral arter doppler bulguları (pulsalite indeksleri, rezistan indeksleri, sistol/diyastol oranları) karşılaştırıldı. Bulgular: Ortalama yaş abortus imminens tanılı hastalarda kontrol grubundan yüksekti (p <0.001). Gruplar arasında uterin ve spiral arter pulsalite indeksleri, rezistan indeksleri, sistol/diyastol oranları arasında istatistiksel anlamlı fark saptanmadı (p> 0.05). Sonuç: İlk trimesterde uterus vasküler yatağını değerlendiren az sayıda çalışma mevcuttur. Uterin vasküler yatağı değerlendirerek, ilk trimesterde abortus imminens prognozunu öngören daha fazla sayıda çalışmaya ihtiyaç vardır.

Anahtar Kelimeler

• Abortus imminens,
• Pulsalite indeks,
• Rezistans indeks ,
• Spiral arter doppler,
• Uterin arter doppler.

References

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