Research Article
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Chemical Composition and Biological Active Substances from Hazelnut Green Leafy Covers

Year 2022, , 999 - 1006, 30.11.2022
https://doi.org/10.18596/jotcsa.1054173

Abstract

This investigation aims to study the perspectives for obtaining natural remedies and food addit­ives from raw plant materials that can be used in food, pharmaceutical, and other industries. The selection of hazelnut green leafy cover as an item is based on the fact that it is a natural organic resource that is now being discarded as waste. In the article, the results are presented about the determination of mineral elements and bioactive compounds in the bio-extracts of 70% ethyl alcohol (BE-III) and distillation water (BE-IV) obtained from the green leafy cover of the plant (Corylus avellane L.) where grow in the north-western region of Azerbaijan. According to our study, BE-III has 25 chemical elements, excluding Rb, for a total of 12.797%, while BE-IV contains 26 chemical elements for a total of 21.347%. Amounts of mac­roelements are 10.4%, and microelements are 2.69% in the content of BE-III, while amounts of macroele­ments are 17.82%, and amounts of microelements are 3.53% in the content of BE-IV. Amounts of organic compounds are 87.2% in the content of BE-III, while their amounts are 78.65% in the content of BE-IV. The amount of Zn, which has antioxidant activity, is 0.009%, and the amount of Se is 0.002% in the con­tent of BE-IV. These values vary in the content of BE-III, the amount of Zn is 0.01%, but the amount of Se is 0.001%. 15 bioactive substances were identified in the content of BE-III bio-extract; however, 5 bioact­ive substances were identified in the content of BE-IV bio-extract. According to our research results, the bio-extract obtained from hazelnut green leafy cover is abundant with antioxidants and bioactive sub­stances with antibacterial activity. For this reason, these bio-extracts can be used as both a food supple­ment and a means of treatment.

Supporting Institution

Sheki Regional Scientific Center, Azerbaijan National Academy of Sciences

References

  • 1. Cerulli A, Lauro G, Masullo M, Cantone V, Olas B, Kontek B, et al. Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Anti­oxidant and Antimicrobial Activities. J Nat Prod [Internet]. 2017 Jun 23 [cited 2022 Aug 8];80(6):1703–13.
  • 2. Simsek A, Aykut O. Evaluation of the microelement profile of Turkish hazelnut ( Corylus avellana L.) vari­eties for human nutrition and health. International Journal of Food Sciences and Nutrition [Internet]. 2007 Jan [cited 2022 Aug 8];58(8):677–88.
  • 3. Özaslan M, Oğuzkan SB, Uğraş S, Can M, Uzun A, Ülger S, et al. Fındık (Corylus avellana L.) Yeşil Kabuk ve Yaprak Ekstraklarında Biyolojik Aktivite Tayini. Journal Of Agriculture and Nature [Internet]. 2016;19(4):373–8.
  • 4. Hoffman A, Shahidi F. Paclitaxel and other taxanes in hazelnut. Journal of Functional Foods [Internet]. 2009 Jan [cited 2022 Aug 8];1(1):33–7.
  • 5. Siriwardhana SSKW, Shahidi F. Antiradical activity of extracts of almond and its by-products. J Amer Oil Chem Soc [Internet]. 2002 Sep [cited 2022 Aug 8];79(9):903–8.
  • 6. Shahidi F, Alasalvar C, Liyana-Pathirana CM. Antioxidant Phytochemicals in Hazelnut Kernel ( Corylus avellana L.) and Hazelnut Byproducts. J Agric Food Chem [Internet]. 2007 Feb 1 [cited 2022 Aug 8];55(4):1212–20.
  • 7. Alasalvar C, Karamać M, Amarowicz R, Shahidi F. Antioxidant and Antiradical Activities in Extracts of Hazelnut Kernel ( Corylus avellana L.) and Hazelnut Green Leafy Cover. J Agric Food Chem [Internet]. 2006 Jun 1 [cited 2022 Aug 8];54(13):4826–32.
  • 8. Abubacker M, Deepalakshmi T. In vitro antifungal potential of bioactive compound methyl ester of hexa­decanoic acid isolated from Annona muricata linn (annonaceae) leaves. Bioscience Biotechnology Research Asia. 2013;10(2):879–84.
  • 9. Azizov F, Shukurlu Y, Khalilov Z. Bio-extract from hazelnut shell. Patent number I 2020 0015.
  • 10. Ermakov A, Arasimovich V, Iarosh N, Peruanskii I, Lukovnikova G, Ikonnikova M. Metody biokhimicheskogo issledovaniia rastenii. 1987. 430 p.
  • 11. Khan Y. Element content analysis of plants of genus Ficus using atomic absorption spectrometer. Afr J Pharm Pharmacol [Internet]. 2011 Mar 31 [cited 2022 Aug 8];5(3):317–21.
  • 12. Mielniczuk Z, Mielniczuk E, Larsson L. Gas chromatography-mass spectrometry methods for analysis of 2- and 3-hydroxylated fatty acids: Application for endotoxin measurement. Journal of Microbiological Meth­ods [Internet]. 1993 Mar [cited 2022 Aug 8];17(2):91–102.
  • 13. Fernández-Lázaro D, Fernandez-Lazaro CI, Mielgo-Ayuso J, Navascués LJ, Córdova Martínez A, Seco-Calvo J. The Role of Selenium Mineral Trace Element in Exercise: Antioxidant Defense System, Muscle Per­formance, Hormone Response, and Athletic Performance. A Systematic Review. Nutrients [Internet]. 2020 Jun 16 [cited 2022 Aug 8];12(6):1790.
  • 14. Tinggi U. Selenium: its role as antioxidant in human health. Environ Health Prev Med [Internet]. 2008 Mar [cited 2022 Aug 8];13(2):102–8.
  • 15. Fallah A, Mohammad-Hasani A, Colagar AH. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men’s Health, Germination, Sperm Quality, and Fertilization. J Reprod Infertil. 2018 Jun;19(2):69–81.
  • 16. Blasco B, Graham NS, Broadley MartinR. Antioxidant response and carboxylate metabolism in Brassica rapa exposed to different external Zn, Ca, and Mg supply. Journal of Plant Physiology [Internet]. 2015 Mar [cited 2022 Aug 8];176:16–24.
  • 17. Chelliah R, Ramakrishnan S, Antony U. Nutritional quality of Moringa oleifera for its bioactivity and anti­bacterial properties. International Food Research Journal. 2017;24(2):825.
  • 18. Ramalhosa E, Delgado T, Estevinho L, Pereira JA. Hazelnut (Corylus avellana L.) Cultivars and Antimi­crobial Activity. In: Nuts and Seeds in Health and Disease Prevention [Internet]. Elsevier; 2011 [cited 2022 Aug 8]. p. 627–36.
  • 19. Azi̇Zov F, Shukurlu Y, Khalilov Z, Atayeva V, Mustafayev N. Chemical composition and biological active substances of bioextracts from hazelnut shell. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji [Internet]. 2021 Jul 30 [cited 2022 Aug 8];
  • 20. Alasalvar C, Shahidi F. Tree Nuts: Composition, Phytochemicals, and Health Effects: An Overview. In: Alasalvar C, Shahidi F, editors. Tree Nuts [Internet]. 1st edition. CRC Press; 2008.
  • 21. Niu X, Wang Z, Zhang L, Quan Y, Wei K. Experimental study of the protective effect of mesosilica-sup­ported 5-hydroxymethylfurfural on UV-induced aging of human dermal fibroblasts. RSC Adv [Internet]. 2018 [cited 2022 Aug 8];8(44):25021–30.
  • 22. Sookwong P, Yodpitak S, Doungkaew J, Jurithayo J, Boonyawan D, Mahatheeranont S. Application of oxygen-argon plasma as a potential approach of improving the nutrition value of pre-germinated brown rice. Journal of Food and Nutrition Research. 2014;2(12):946–51.
Year 2022, , 999 - 1006, 30.11.2022
https://doi.org/10.18596/jotcsa.1054173

Abstract

References

  • 1. Cerulli A, Lauro G, Masullo M, Cantone V, Olas B, Kontek B, et al. Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Anti­oxidant and Antimicrobial Activities. J Nat Prod [Internet]. 2017 Jun 23 [cited 2022 Aug 8];80(6):1703–13.
  • 2. Simsek A, Aykut O. Evaluation of the microelement profile of Turkish hazelnut ( Corylus avellana L.) vari­eties for human nutrition and health. International Journal of Food Sciences and Nutrition [Internet]. 2007 Jan [cited 2022 Aug 8];58(8):677–88.
  • 3. Özaslan M, Oğuzkan SB, Uğraş S, Can M, Uzun A, Ülger S, et al. Fındık (Corylus avellana L.) Yeşil Kabuk ve Yaprak Ekstraklarında Biyolojik Aktivite Tayini. Journal Of Agriculture and Nature [Internet]. 2016;19(4):373–8.
  • 4. Hoffman A, Shahidi F. Paclitaxel and other taxanes in hazelnut. Journal of Functional Foods [Internet]. 2009 Jan [cited 2022 Aug 8];1(1):33–7.
  • 5. Siriwardhana SSKW, Shahidi F. Antiradical activity of extracts of almond and its by-products. J Amer Oil Chem Soc [Internet]. 2002 Sep [cited 2022 Aug 8];79(9):903–8.
  • 6. Shahidi F, Alasalvar C, Liyana-Pathirana CM. Antioxidant Phytochemicals in Hazelnut Kernel ( Corylus avellana L.) and Hazelnut Byproducts. J Agric Food Chem [Internet]. 2007 Feb 1 [cited 2022 Aug 8];55(4):1212–20.
  • 7. Alasalvar C, Karamać M, Amarowicz R, Shahidi F. Antioxidant and Antiradical Activities in Extracts of Hazelnut Kernel ( Corylus avellana L.) and Hazelnut Green Leafy Cover. J Agric Food Chem [Internet]. 2006 Jun 1 [cited 2022 Aug 8];54(13):4826–32.
  • 8. Abubacker M, Deepalakshmi T. In vitro antifungal potential of bioactive compound methyl ester of hexa­decanoic acid isolated from Annona muricata linn (annonaceae) leaves. Bioscience Biotechnology Research Asia. 2013;10(2):879–84.
  • 9. Azizov F, Shukurlu Y, Khalilov Z. Bio-extract from hazelnut shell. Patent number I 2020 0015.
  • 10. Ermakov A, Arasimovich V, Iarosh N, Peruanskii I, Lukovnikova G, Ikonnikova M. Metody biokhimicheskogo issledovaniia rastenii. 1987. 430 p.
  • 11. Khan Y. Element content analysis of plants of genus Ficus using atomic absorption spectrometer. Afr J Pharm Pharmacol [Internet]. 2011 Mar 31 [cited 2022 Aug 8];5(3):317–21.
  • 12. Mielniczuk Z, Mielniczuk E, Larsson L. Gas chromatography-mass spectrometry methods for analysis of 2- and 3-hydroxylated fatty acids: Application for endotoxin measurement. Journal of Microbiological Meth­ods [Internet]. 1993 Mar [cited 2022 Aug 8];17(2):91–102.
  • 13. Fernández-Lázaro D, Fernandez-Lazaro CI, Mielgo-Ayuso J, Navascués LJ, Córdova Martínez A, Seco-Calvo J. The Role of Selenium Mineral Trace Element in Exercise: Antioxidant Defense System, Muscle Per­formance, Hormone Response, and Athletic Performance. A Systematic Review. Nutrients [Internet]. 2020 Jun 16 [cited 2022 Aug 8];12(6):1790.
  • 14. Tinggi U. Selenium: its role as antioxidant in human health. Environ Health Prev Med [Internet]. 2008 Mar [cited 2022 Aug 8];13(2):102–8.
  • 15. Fallah A, Mohammad-Hasani A, Colagar AH. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men’s Health, Germination, Sperm Quality, and Fertilization. J Reprod Infertil. 2018 Jun;19(2):69–81.
  • 16. Blasco B, Graham NS, Broadley MartinR. Antioxidant response and carboxylate metabolism in Brassica rapa exposed to different external Zn, Ca, and Mg supply. Journal of Plant Physiology [Internet]. 2015 Mar [cited 2022 Aug 8];176:16–24.
  • 17. Chelliah R, Ramakrishnan S, Antony U. Nutritional quality of Moringa oleifera for its bioactivity and anti­bacterial properties. International Food Research Journal. 2017;24(2):825.
  • 18. Ramalhosa E, Delgado T, Estevinho L, Pereira JA. Hazelnut (Corylus avellana L.) Cultivars and Antimi­crobial Activity. In: Nuts and Seeds in Health and Disease Prevention [Internet]. Elsevier; 2011 [cited 2022 Aug 8]. p. 627–36.
  • 19. Azi̇Zov F, Shukurlu Y, Khalilov Z, Atayeva V, Mustafayev N. Chemical composition and biological active substances of bioextracts from hazelnut shell. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji [Internet]. 2021 Jul 30 [cited 2022 Aug 8];
  • 20. Alasalvar C, Shahidi F. Tree Nuts: Composition, Phytochemicals, and Health Effects: An Overview. In: Alasalvar C, Shahidi F, editors. Tree Nuts [Internet]. 1st edition. CRC Press; 2008.
  • 21. Niu X, Wang Z, Zhang L, Quan Y, Wei K. Experimental study of the protective effect of mesosilica-sup­ported 5-hydroxymethylfurfural on UV-induced aging of human dermal fibroblasts. RSC Adv [Internet]. 2018 [cited 2022 Aug 8];8(44):25021–30.
  • 22. Sookwong P, Yodpitak S, Doungkaew J, Jurithayo J, Boonyawan D, Mahatheeranont S. Application of oxygen-argon plasma as a potential approach of improving the nutrition value of pre-germinated brown rice. Journal of Food and Nutrition Research. 2014;2(12):946–51.
There are 22 citations in total.

Details

Primary Language English
Journal Section Articles
Authors

Farhad Azizov 0000-0002-9438-066X

Zarbali Khalılov This is me 0000-0002-7201-8678

Vefa Atayeva 0000-0002-9886-2500

Nurmammad Mustafayev This is me 0000-0002-8493-0429

Hılal Imanlı This is me 0000-0002-5251-7867

Publication Date November 30, 2022
Submission Date January 7, 2022
Acceptance Date July 26, 2022
Published in Issue Year 2022

Cite

Vancouver Azizov F, Khalılov Z, Atayeva V, Mustafayev N, Imanlı H. Chemical Composition and Biological Active Substances from Hazelnut Green Leafy Covers. JOTCSA. 2022;9(4):999-1006.