Physicochemical Parameters Affecting Lipase Performance: Including New Methods and Techniques Increasing Lipase Activity
Abstract
Lipases are versatile green biocatalysts from the hydrolase family, valued for their high selectivity, specificity, and catalytic efficiency in diverse industrial applications, including pharmaceuticals, food, and bioenergy. Their activity and productivity are strongly influenced by a range of physicochemical and operational factors. This review summarizes the key parameters affecting lipase performance, including temperature, pH, metal ions, nitrogen sources, surfactants, agitation speed, and incubation time. The roles of substrate-related factors-such as concentration, derivative type, substrate ratio, and enzyme loading-are also described. In addition, recent methods and emerging techniques aimed at enhancing lipase activity and reducing product losses, such as lipase engineering, immobilization, bioimprinting, interfacial imprinting, the use of conventional organic co-solvents, additives, natural deep eutectic solvents, and multi-lipase systems, are outlined. By compiling and organizing current knowledge, this work serves as a practical reference for optimizing lipase-based processes in both research and industrial contexts.
Keywords
lipase immobilization lipase engineering physicochemical parameters deep eutectic solvents.
Thanks
The authors gratefully acknowledge the support of Yildiz Technical University and access to relevant databases.
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Details
| Primary Language | English |
|---|---|
| Subjects | Biochemistry and Cell Biology (Other) |
| Journal Section | Review |
| Authors | |
| Submission Date | August 21, 2025 |
| Acceptance Date | December 4, 2025 |
| Publication Date | January 30, 2026 |
| Published in Issue | Year 2026 Issue: 2026-1 |
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Please do not submit PDF copies of your articles for preliminary control. We accept Microsoft Word DOC, Microsoft Word DOCX, and LibreOffice ODT. We directly work on the manuscript, forming changes that are trackable.
Please do not submit your work again from the very beginning, if the management requires that you prepare a revision. Just browse to your existing submission and use the upload module to upload the newer version. If you are stuck, please send the revised article with an e-mail to the managing editor at jotcsa@turchemsoc.org.
Our journal will use, beginning from 10(1), a manual heading-based system with numbers, like 1. INTRODUCTION, 2.1. Materials and Methods, etc. More information will be found in the template file.
You may download the article templates, depending on your word processor, from the link below. Kindly recall that we do not have any LaTeX templates for now:
*Article template (for Microsoft Word)
*Article template (for LibreOffice Writer)
*Potential reviewer recommendation form
Reaction schemes usually used for reactions and related material will use Arial or Verdana, preferably at 9 or 10 points, inside the figures. Our journal recommends that authors use "Chemdraw" or "ChemSketch" or "MarvinSketch" softwares. Directly pasting from the drawing application into the word processor software is NOT recommended. Please use the "paste special" feature to paste it as a metafile image.
Citing: Our journal uses a number-based reference system, and the number is given in normal parenthesis like (17). Other examples include (1-3, 17), (1-3, 17, 19-21), etc. The above-mentioned reference managers have the required tools to create citations in the text. When inserting a new paragraph, the manager will safely rearrange the citations, refreshing the numbers.
For presentation of proton or carbon nuclear magnetic resonance data, please see the article template above.
The words Scheme 1, Figure 1, etc., will have a full stop at the end of the caption. The caption text will be centered on the page.
Supplementary information: The authors are encouraged to use supplementary information, for detailing the study with spectral data, crystal structure refinement data, and other types of material should you recommend including. All types of synthetic procedures will be included in the main text. Supplementary files will be added as a new file by the editors.
Usage of the units: The units will be, where possible, SI-based and the style g/mL will be preferred over g.mL-1. Please do not mix these two and be consistent throughout the manuscript about using the units.
Ethical Principles and Publication Policy
Journal's Ethical Principles and Rules
Our journal adheres to international standards and COPE (Committee on Publication Ethics) standards and publishes articles by referring to them.
ETHICS
Guidelines for Editors: An editor (editors and section editors) should objectively evaluate all articles submitted for publication, evaluating each on its own merits, regardless of race, religion, nationality, gender, seniority, or institutional affiliation. An editor should review and deal with a manuscript submitted for publication at reasonable speed. The editor has sole responsibility for accepting or rejecting an article for publication. The editor may seek assistance on an article from experts selected for their expertise and fair judgment. Until the review process is complete, the editor should not disclose any information about the manuscript under review to anyone other than the author and appointed reviewers. Intellectual independence of the authors should be respected.
Authors: Our journal considers the person responsible for at least a part of the work as the author. Authors should be able to explain the problem in the study in depth. All authors for our journal are responsible for the content they submit. The corresponding author is responsible for accepting all authors from the first submission of the article and informing them about the submission process. If accepted, all authors are obliged to grant the publishing license on their behalf. Our journal assumes that the submission of the article is the complete agreement of all authors. For articles with more than 8 authors, all authors must make a statement, detailing what their contribution to the article is.
It is not acceptable for JOTCSA to consider for publication anything that has been previously published, in whole or in part, in other journals. Simultaneous submissions to JOTCSA and any other journal is considered a gross misconduct and all authors are strictly prohibited and all previous publications in JOTCSA are publicly retracted. Plagiarism and self-plagiarism will be treated in the same way. Multiple articles that cover closely related topics and/or variables are not recommended (if they can not be included in a single article).
For studies involving biological materials from animals and humans, the authors should state in their articles (preferably in the Acknowledgments section) from the authorized committee of their institution, as well as from the biological material donors or their relatives, that they performed the study in accordance with the Declaration of Helsinki, and submit “informed consent forms” obtained from the ethics committee.
Reviewers: JOTCSA invites colleagues to review their submissions based on their expertise, curriculum, and willingness to voluntarily review. By agreeing to review a draft, the referee commits to doing so in a timely manner. Delays are extremely negative for the review process and make it take much longer than it should. When asked to reply to an invitation email from a reviewer, they are kindly wanted to respond to the invitation email by stating whether they are willing to review the article. This is a gesture of courtesy and avoids delays. By agreeing to review a manuscript, the referee declares that there are no conflicts of interest and that their review is for the enrichment and advancement of science. Reviewers who accept our requests and respect deadlines are scored positively and any final submissions they can submit to JOTCSA are given priority.
Journal's Open Access Policy: Our journal is open access and uses Dergipark's open access notifications. As soon as the article is published, it is rendered open access and anyone (all readers) can access it without paying any fee.
The Budapest Open Access Statement (BOAI) on this subject reads:
“By 'open access' to this literature, we mean its free availability on the public internet, which allows any user to read, download, copy, distribute, print, search or link to, search for indexing the full texts of these articles. They may not be transferred to software as data or used for any other legal purpose other than financial, legal or technical barriers that are an integral part of gaining access to the Internet. The only restriction on duplication and distribution, and the sole role of copyright in this field, should be to give authors control over the integrity of their work and the right to be properly accepted and cited.”
Journal's Publication Policy: Our journal charges article processing fee (APC, 50 USD or 50 EUR for each article). The journal uses a double-blind peer-review policy to evaluate articles. The author presents their material and a secretary makes an initial assessment of it and decides whether the article is suitable for further processing or a decision of rejection has been made. The same is true for all articles with a similarity score higher than 20% by Intihal net (formerly, we used Ithenticate). It is welcome if the author decides to resubmit the material after substantial revision. When the article is accepted for peer review, the editor-in-chief decides who will be the section editor and forwards the article file to them. The section editor calls at least two referees who are experts in their fields and waits for their evaluations under considerable period of time. The section editor collects the evaluations from the referees, makes a short list of the referees' suggestions, and sends the decision (acceptance, minor revision, major revision, rejection) to the author along with the article. These operations are performed by Dergipark, so great time is saved. The author receives the report and starts working, answers the questions, and submits the corrected article and the processed report. In some cases, the section editor finds this sufficient and does not need to send the revised material again to the reviewers. Otherwise, the referees comment on the revision and make their final decision. There are rare occasions when a revised draft needs additional editing sessions and the process starts over. After revisions, the article is likely accepted and forwarded to the copyeditor, who examines the use of English and makes corrections to the article. The copied article is forwarded to the Layout Editor, who creates the final view of the draft and the final PDF file. The final PDF file is exported to the proofreader and retrieved as needed as a list of revisions or markup directly on the PDF. The PDF file is corrected and submitted ready for publication, the short name of the PDF file is set, the reference list is checked, the author list is checked, and the ORCID IDs are entered. As the last step, the title, abstract, publication date, and page range are checked and the DOI name is requested. If all go well, the journal system allows the applicant to have a DOI name, then the article is registered in a journal issue, the ranking is determined, and the process is approved. The article is published and can be viewed on the journal's website. If something still needs to be fixed, the process starts again and the corrected article PDF replaces the old one. It should be noted that if the issue is published, there are five extra days to make changes. No changes are allowed after this period and the Erratum document should be issued and published in the next issue.
The time it takes to evaluate an article varies from article to article; however, it takes between two and four months to get results. Exceptions occur when a reviewer responds quickly or when the author prepares the report a few days after receiving it. In these cases, the assessment only takes a month or two. On the other hand, reviewers and authors may have delays, partly because the e-mail is caught by the junk mail filters and they are not aware of the progress; therefore undesirable delays occur. A similar reason is that the e-mail address of the reviewer or author is blocked or exceeded the quota, so the message never reaches the user.
Conflict of interest: Authors should declare their conflict of interest (if any) at the end of the article. It should also be declared that there is no conflict of interest.
If there is a conflict of interest, the author or authors should be specific and state any financial affiliation of all authors of the article with any sponsoring organization and any for-profit interests represented by the organization and any product discussed or debated or for-profit.
Withdrawal: There is a form prepared by Dergipark that editors can fill in regarding issues of withdrawal, and Dergipark will be informed.
Sometimes it can be done to make a change that has already been published. The journal's editorial team and staff (if necessary) work together to make necessary changes according to the journal's policies and COPE's guidance.
Necessary changes (minor errors do not count here) include a post-publication statement, which is permanently linked to the original article. The mentioned changes may be an update notice, an Expression of Concern, a Retraction notice, or a removal notice (which is considered very rare).
To ensure transparency in records and ensure the integrity of recorded records, post-publication notices are added to original articles. Access to all post-broadcast announcements is free, starting from the broadcast content.
Version of Record
The published article "Version of Record" is the final, definitive, and reproducible version in the collected records.
The Record Version of this product consists of the following items:
a) The article in its final form, including (but not limited to) abstract, text, references, bibliography, tables without groups, drawings and data, and revised and accepted after peer-review.
b) Supplementary material (if any)
Authors should inform the journal as soon as possible if they find errors in their published articles. It becomes especially important to interpret the data or find errors in the information presented that will change the data. The corresponding author has the responsibility of organizing a physical or virtual meeting of all co-authors before any written development requests are made.
In particular, the corresponding author is free to make corrections if he/she considers that the article needs to be corrected. In such a case, the run manager or managing editor should be contacted.
Notification of change
Preparing a record statement for the equipment requirement of an error or omission in which the interpretation of the article may be affected but the scientific integrity or the original structure can be preserved intact.
The corresponding author and all other authors must write and approve the improvement of their articles. It is very rare that an error in the publishing process will be requested by the system rules journal for a correction notice without the direct integrity of the authors. In this very rare case, the journal will do its best to inform authors.
Changes sometimes lead to a full review of the manuscript and, if there are errors in question, the authors should provide further information before the revision is approved.
The journal will distinguish between major and minor mistakes. Update notices, major errors or omissions, changes to the comments of the article are considered changes, but the overall integrity of the representation remains intact. Minor errors are considered errors or omissions that do not impair the reliability of the article's interpretation or the reader's interpretation.
Major bugs will always have a separate notice of errors along with the article. This notice should contain the details of the error and report its registration in the version of records.
Under these conditions their journal will:
a) Correct the online article.
b) Publish the corrected version electronically in a separate correction notice.
c) A footnote showing the electronic links of the correction notice is added to the article.
d) Separate the update notice into pages and publish the updated version of the journal.
e) Provide free viewing of the notification.
f) A separate correction notice may not be added to minor errors. Instead, a footnote will be added to the article giving the reader detailed information that the article was scanned.
g) Concerns regarding the integrity of a published article should be reported to the Editor or via e-mail through the Publisher.
Retractions
A Retraction notice is issued if a grave error (e.g. in developments or analysis) invalidates the results in the product or if there is a misconduct in research or publication (e.g. research without the necessary ethical approvals, acceptance data, natural images, plagiarism, duplicate publication, etc.).
It is determined in accordance with the journal's policies and COPE rules. Following the decision, a comprehensive investigation will be conducted by the journal’s editorial team in collaboration with the publishing editorial team. Authors and institutions may request that their justifications combine the retraction criteria and that their individual articles be added back.
Retractions should be made to correct edits and should not be interpreted as punishment for authors.
They will not be able to withdraw from:
a) Abuse (e.g., data forgery or image manipulation) or error (e.g., miscalculation or selective error) results in no one being trustworthy or there is clear evidence.
b) Findings have previously been published elsewhere without appropriate reference, permission or justification (e.g. unnecessary or duplicate publication conditions).
c) The research is an organization of plagiarism.
d) The editor no longer has confidence in the existence or integrity of the articles.
e) There is evidence or concerns that authorship has been demonstrated.
f) The published reference manipulation is clearly visible.
g) Where there is evidence of negative peer reviews or systematic manipulation.
h) Evidence of an unethical link will not be changed or evidence of a violation of publication policies will not be distorted.
i ) Authors have deliberately provided false or inaccurate information or violated a warranty provided by Author Publishing.
Once an article completes the inclusion process, the journal will perform the following actions:
a) Add a “withdrawn” watermark to the published Registration Version of the article.
b) Publish a separate retraction notice on the journal website titled 'Retraction: [article title]' which will give credit to the article.
c) Separate the retraction statement into pages and publish the journal's online features.
Expressions of concern
At some temperature, an Expression of Concern is provided in which concerns of a serious nature are expressed (using dissemination of research or publication elsewhere), but are disregarded when the outcome of the investigation is not certain or due to various complexities the investigation will not be considered for review. A significant period of time has been completed. This may be due to ongoing institutional investigations or other circumstances beyond the journal's control.
Once the investigation is complete, a Retraction or request may be received following the original article as well as the Expression of Concern. All broadcasts will remain part of the permanent wallet.
Explanations of statements are taken into account as follows:
There are tentative findings regarding authors' research or publishing misconduct, but it is necessary to inform readers of what the concerns are.
There are well-founded concerns that the findings are unreliable or that abuse may occur, but there has been limited cooperation between the authors' institution(s) where concerns have been raised.
Allegations of misconduct are made in relation to an investigation that was not fair, systematic or accurate or unclear in relation to the publication.
An investigation is ongoing, but a resolution will not be found for a long time and concerns are expected to inform existing readers.
The Expression of Concern will be linked back to the relevant published article.
Removal of Article
In a rare version where issues are not retracted or resolved via information of notification will be removed. Journal management will consider publications of a widely published article that:
a) The article contains content that may pose a risk of serious harm if ignored or followed.
b) The article contains content that violates the privacy rights of an employment agreement.
c) The article is defamatory or violates other legal rights.
d) An article is subject to court decision.
If an article from JOTCSA is published, a cease and desist notice will be served instead.
Updates and scientific discussions on published articles
Attachments
An addendum is an announcement of the addition of information to an article.
Addenda do not contradict the original publication and are not used to correct errors (for which a confirmation notice will be issued), but where the author needs to pack or add some important information, this may be published as an addendum.
Appendices are peer-reviewable according to journal policy and are sometimes subject to oversight by journal editors.
All appendices are electronically linked to the published article to which they refer.
Comment (including reply and reply threads)
Comments are short articles that outline an observation on a published article. If a comment on a published article is forwarded to the operation of the journal, it may be subject to peer review. The comment will be shared with the authors of the published article, who are invited to submit a response.
This response of the author may again be subject to peer review and will be shared with the commenter who may be invited to send a response. The response may be peer reviewed and shared with the authors of the published article. No further correspondence will be pursued for publication. The editor may decide to reject correspondence at any time before the comment, response or response is finalized.
All posted comments, replies and replies are linked to relevant published articles.
Pop-up notifications
If the Publishing Ethics and Integrity team deems it necessary, an open notice may be temporarily added to the online version of the article to prompt readers to investigate and report the article. This is not a permanent note (unlike an Expression of Concern, application, or Withdrawal notice), but is because you are continuing an investigation. Please note that among these, they were not included in the researched article.
Authors who publish in this journal agree to the following terms:
Creative Commons Attribution License: Our journal will use a “CC BY-NC-ND 4.0” or “Attribution-NonCommercial-NoDerivatives 4.0 International” license. This license requires that reusers give credit to (mention of) the creator. It allows reusers to copy and distribute the material in any medium or format in unadapted form and for noncommercial purposes only.
In the license, the abbreviations mean the following:
BY: Credit must be given to you, the creator.
NC: Only noncommercial use of your work is permitted. Noncommercial means not primarily intended for or directed towards commercial advantage or monetary compensation.
ND: No derivatives or adaptations of your work are permitted.
For your information,
Prof. Dr. Hasan KÜÇÜKBAY
Chief editor, JOTCSA
Price Policy
The authors must complete this document (https://dergipark.org.tr/tr/download/journal-file/31807) before submission. This document clarifies that all authors consent on paying the APC before acceptance of the article.
The authors will pay 50 USD or 50 EUR (see below for details) after they have been notified that the article has been accepted and before the post-production has started.
Explanation area: Please enter the ID of article (like 1432470) and the name of corresponding author. Kindly forward the receipt to Mr. Tahsin Kızılay, e-mail: taum74@gmail.com. He is the manager of the Society, at https://www.turchemsoc.org.
a) Turkish authors are kindly directed to TR03 0011 1000 0000 0140 1228 71 IBAN number with Turkish Liras amounting to 50 USD or 50 EUR (with Daily Turkish Republic Central Bank Sales Price).
b) Authors from European countries, please send the price to TR56 0011 1000 0000 0051 3336 46 EUR IBAN number.
Please send your APC sums (Swift or Western Union) exclusive of the processing fee, amounting to exactly 50 USD.
Western Union payments are sent to the manager of the Society, Mr. Tahsin KIZILAY.
c) For other territories, please transfer the sum one of the USD or EURO accounts or Western Union (exclusive of the processing fee for all transactions):
QNB Finansbank, Osmanbey Branch, Sisli, Istanbul
Account No: (For USD) 51 333 519 / (For EUR) 51 333 646
IBAN, USD: TR90 0011 1000 0000 0051 3335 19
IBAN, EUR: TR56 0011 1000 0000 0051 3336 46
SWIFT CODE: FNNBTRISOPS
ACCOUNT NAME: Tahsin Kızılay
Indexes
Journal Boards
Editor-in-Chief
H. Küçükbay was born in Yeşilyurt-Malatya, TURKEY. He received his BS degree from the University of Inönü (valedictorian), Malatya, Turkey in 1985, and He graduated with a MSc and a PhD in organic chemistry from the University of Inönü in 1988 and 1993, respectively. He worked for one year as researcher at Professor Michael F. Lappert's research laboratory at University of Sussex, UK in 1991-1992, six weeks as researcher at Professor Pierre H. Dixneuf’s research laboratory at University of Rennes1, France in 1995, three months as research scholar at Professor Alan R. Katritzky’s reserach laboratory at University of Florida, Gainswille, USA in 2012 and four months as visitor researcher at Professor Claudiu T. Supuran’s reserach laboratory at University of Florence, Firenze, Italy in 2015 and 2018. He has been to University of Crete-GR in 2007 and RWTH-Aachen-GER for a short time in 2008 within the framework of the Erasmus Project. He received his Associate Professor degree from the Turkish Council of Higher Education in 1997. He received his Professor degree from İnönü University in 2003. His research interests have been in electron-rich olefins, their carbenmetal complexes and catalytic properties such as cyclisation and Suzuki, Heck and Sonogashira C-C cross coupling reactions, synthesis and biological properties of peptide and their conjugates, synthesis of heterocyclic compounds, particularly benzimidazole and benzothiazole derivatives and their microbiological properties. He has over 100 scientific articles in SCI/SCI-Exp covered journals and one patent. He chaired the 5th International Organic Chemistry Congress held in Malatya-Turkey in 2021. He acts as Editor-in Chief of Journal of the Turkish Chemical Society, Section A: Chemistry (JOTCSA) and Associate Editor Frontiers in Organic Chemistry. He has been working since 1986 at University of Inönü. He is married with two sons.
Address: İnönü University, Faculty of Sciences and Arts, Chemistry Department, 44280 Malatya-TURKEY
E-mail: hkucukbay@inonu.edu.tr or hkucukbay@gmail.com
Analytical Chemistry
Biochemistry
Hakkında, Web Adresi, ORCID bilgileri eksik.
Computational Chemistry
Ph.D. in Chemistry Inonu University, Turkey Institute of Science | 2008 – 2013
M.Sc. in Chemistry Firat University, Turkey Institute of Science | 2003 – 2005
Boulebd Houssem received his PhD in organic chemistry in 2016. He is currently a faculty member at the University of Constantine 1, in the Chemistry Department of the Faculty of Exact Sciences. His research interests include organic and computational chemistry, biochemistry and medicinal chemistry. Houssem is actively involved in several projects, including the synthesis of multifunctional antioxidants, the thermodynamic and kinetic study of the antioxidant activity of natural compounds, and the computational design of drugs. His work aims to advance the understanding and development of compounds with significant therapeutic potential.
Crystallography
Prof. Dr. Sibel Demir Kanmazalp is a physicist at Gaziantep University. She specializes in crystallography, solid-state physics, and theoretical studies of molecular and crystalline materials.
Her work combines experimental techniques such as single-crystal X-ray diffraction (SC-XRD) with computational methods, including Density Functional Theory (DFT), molecular electrostatic potential (MEP) analysis, and band structure calculations. She has contributed to the understanding of noncovalent interactions, halogen bonding, and thermoelectric properties of advanced materials.
Prof. Demir Kanmazalp has authored numerous peer-reviewed publications and actively participates in national and international research collaborations.
Electrochemistry
After graduating in 1983 from Atatürk University, Faculty of Science, Department of Chemistry, he completed his Master's and Doctorate between 1983-1990. He became Assistant Professor in 1990 and Associate Professor in 1997. In 1999, he started to work as an Associate Professor in the Department of Analytical Chemistry, Faculty of Pharmacy. In 2003, he became a Professor. His research interests are: Method Development and Validation of Active Pharmaceutical Ingredient Analysis in Various Media, Spectroscopic Methods, Chromatographic Methods, Chemometric Methods and Metabolomics.
Translated with DeepL.com (free version)
Food Chemistry
Özge Süfer, Osmaniye Korkut Ata Üniversitesi (OKÜ) Mühendislik ve Doğa Bilimleri Fakültesi Gıda Mühendisliği Bölümünde “Doçent Doktor” olarak görev yapmaktadır. Ege Üniversitesi Mühendislik Fakültesi Gıda Mühendisliği Bölümü'nden 2010 yılında mezun olmuştur. Akademik kariyerine 2011 yılında OKÜ Gıda Mühendisliği Bölümünde Araştırma Görevlisi olarak başlamış olup, ertesi yıl Ege Üniversitesi’nden Yüksek Lisans derecesi almıştır. 2018 yılında Mersin Üniversitesi Gıda Mühendisliği Bölümü’nde doktorasını tamamladıktan sonra, 2022 yılında OKÜ Gıda Mühendisliği Bölümü’ne doktor öğretim üyesi olarak atanmıştır. 2023 yılında doçent doktor ünvanını alan araştırmacı, pek çok bilimsel eser üretmiş ve dersler vermiştir. 39 adet SCI, 5 adet E-SCI ve 18 adet ULAKBİM tarafından taranan ulusal dergilerde yayınlanmış makalesi bulunan Özge Süfer, 2016 yılında Cartegena Politeknik Üniversitesi’nde (İspanya) düzenlenen, 3. Mikrodalga Enerji Uygulamaları Küresel Kongresi’nden AMPERE (Araştırma ve Eğitim için Avrupa Mikrodalga Gücü Derneği) ödülüne, 2021 yılında OKÜ tarafından Mühendislik Temel Alanında Performans Ödülü’ne layık görülmüştür. Pek çok ulusal ve uluslararası dergide yayın hakemliği yapan Dr. Süfer, SCOPUS endeksinde taranan Journal of Turkish Chemical Society Section A: Chemistry dergisinde alan editörü, ULAKBİM endeksinde taranan Osmaniye Korkut Ata University Journal of Natural and Applied Sciences dergisinde editör yardımcısı ve de SCI endeksinde taranan Frontiers in Nutrition isimli dergide ise inceleme editörü olarak görev yapmaktadır. Halihazırda, 12 adet COST destekli projede çalışma grubu üyesi olarak yer almaktadır.
Forensic Chemistry
Orhan Destanoğlu was born in Istanbul. He completed his undergraduate studies at Trakya University, Department of Chemistry in 2005. He received his MSc (2009) and PhD (2016) from Istanbul Technical University, Department of Chemistry. He worked as an Expert Chemist at the Department of Chemistry, Council of Forensic Medicine (ATK) between 2014 and 2020. He has been working at İstanbul University-Cerrahpasa, Institute of Forensic Sciences and Legal Medicine, Department of Science since 2020. He received the title of Associate Professor from the Turkish Council of Higher Education in 2023. Orhan Destanoğlu, an expert in Forensic Chemistry and Analytical Chemistry, has been a member of the Turkish Chemical Society since 2018 and a section editor at Journal of the Turkish Chemical Society Section A: Chemistry (JOTCSA) since 2023.
Address: İstanbul University-Cerrahpasa, Institute of Forensic Sciences and Legal Medicine, Department of Science, 34500, Büyükçekmece, Istanbul, TÜRKİYE.
Email: orhan.destanoglu@iuc.edu.tr
ORCID: https://orcid.org/0000-0003-2477-0694
Inorganic Chemistry
Dursun Ali KÖSE was born in Samsun Terme. He completed his undergraduate and graduate studies at Kars Kafkas University, Department of Chemistry, with his thesis titled "Synthesis of Nicotinamide and Diethylnicotinamide Complexes of Acetylsalicylates and Investigation of their Structures". Doctor title: Prof. Dr. He received his thesis title "Preparation and Structure Investigation of Biopotent Boron Compounds with Hydroxy-Functionalized Organic Molecules" at Hacettepe University, Department of Inorganic Chemistry, under the supervision of Birgül KARAN in 2008. Between 2009 and 2010, he worked as Research Assistant at Kafkas University, Department of Chemistry. See Dr. After working as an assistant at Çorum Hitit University, Department of Chemistry. Assoc. Dr. was appointed as. In 2010, for postdoctoral studies, Prof. Dr. It was found in Mike Becket's laboratories at the Bangor/Wales School of Chemistry. He received the title of Associate Professor at Hitit University in 2013 and the title of Professor at the same University in 2018.
Köse has around 140 scientific articles scanned by international indexes, around 90 papers presented at international conferences, and his studies on metal complexes and boron esters of biologically active ligands continue. He also has studies in the fields of Environment and Waste Management and Occupational Health and Safety.
Organic Chemistry
01/03/2023- to date
Associate Professor
University of Florence Department of Neuroscience, Psychology, Drug Area and Child Health (NEUROFARBA). (IT)
01/03/2020 to 28/02/2023
Assistant Professor tenure track (RTD-b)
University of Florence Department of Neuroscience, Psychology, Drug Area and Child Health (NEUROFARBA). (IT)
01/03/2018-29/02/2020
Junior Assistant Professor (RTD-a)
University of Florence Department of Neuroscience, Psychology, Drug Area and Child Health (NEUROFARBA). (IT)
01/07/2016 – 30/06/2017
Postdoctoral Fellow
University of Florence Department of Neuroscience, Psychology, Drug Area and Child Health (NEUROFARBA). (IT)
▪ Research activities within the field of drug Design Medicinal Chemistry
01/09/2015-11/12/2015
Lecturer
University of New Haven, Tagliatela College of Engineering, Department of Chemistry and Chemical Engineering, Meadow Campus.
▪ Teaching activities in Theoretical Chemistry and applied organics synthesis; General Organic and Inorganic Chemistry
01/03/2010 - 31/06/2016
Postdoctoral Fellow
University of Florence-Department of Chemistry "Ugo Schiff". (IT)
▪ Research activities within the field of drug Design Medicinal Chemistry
01/11/2008-29/02/2009
Postdoctoral Fellow
University of Florence-Department of Chemistry "Ugo Schiff". (IT)
Research activities within the field of drug Design Medicinal Chemistry
01/01/2008 - 31/10/2008
Postdoctoral Fellow
University of Sassari (IT)
▪ Research activities within the field of drug Design Medicinal Chemistry
Medicinal Chemistry, Drug Design, Development of modulators of metalloenzymes of biomedical interest
01/02/2007 - 22/12/2007
Postdoctoral Fellow
Massachusetts Institute of Technology (MIT, USA)-Department of Chemistry.
▪ Research activities within the synthesis of complex organic molecules of natural origin
Drug Design, Advanced organic synthesis
2004-2007
PhD in Chemistry
University of Bristol, School of Chemistry (UK)
Synthesis and identification in NMR-solution of Cationic species. Mechanistic studies on Prins- and Prins-type reactions
2002
Degree in Chemistry and Pharmaceutical Technologies
University of Sassari (IT) (110/110 with honors)
H. Küçükbay was born in Yeşilyurt-Malatya, TURKEY. He received his BS degree from the University of Inönü (valedictorian), Malatya, Turkey in 1985, and He graduated with a MSc and a PhD in organic chemistry from the University of Inönü in 1988 and 1993, respectively. He worked for one year as researcher at Professor Michael F. Lappert's research laboratory at University of Sussex, UK in 1991-1992, six weeks as researcher at Professor Pierre H. Dixneuf’s research laboratory at University of Rennes1, France in 1995, three months as research scholar at Professor Alan R. Katritzky’s reserach laboratory at University of Florida, Gainswille, USA in 2012 and four months as visitor researcher at Professor Claudiu T. Supuran’s reserach laboratory at University of Florence, Firenze, Italy in 2015 and 2018. He has been to University of Crete-GR in 2007 and RWTH-Aachen-GER for a short time in 2008 within the framework of the Erasmus Project. He received his Associate Professor degree from the Turkish Council of Higher Education in 1997. He received his Professor degree from İnönü University in 2003. His research interests have been in electron-rich olefins, their carbenmetal complexes and catalytic properties such as cyclisation and Suzuki, Heck and Sonogashira C-C cross coupling reactions, synthesis and biological properties of peptide and their conjugates, synthesis of heterocyclic compounds, particularly benzimidazole and benzothiazole derivatives and their microbiological properties. He has over 100 scientific articles in SCI/SCI-Exp covered journals and one patent. He chaired the 5th International Organic Chemistry Congress held in Malatya-Turkey in 2021. He acts as Editor-in Chief of Journal of the Turkish Chemical Society, Section A: Chemistry (JOTCSA) and Associate Editor Frontiers in Organic Chemistry. He has been working since 1986 at University of Inönü. He is married with two sons.
Address: İnönü University, Faculty of Sciences and Arts, Chemistry Department, 44280 Malatya-TURKEY
E-mail: hkucukbay@inonu.edu.tr or hkucukbay@gmail.com
Pharmaceutical chemistry
https://personel.trakya.edu.tr/anilyilmaz/
Photochemistry
Physical Chemistry
Polymer Chemistry
Emrah ÇAKMAKÇI, 1985 yılında İstanbul’da doğdu. Liseyi, Şişli Anadolu Lisesi’nde okudu ve sonra Marmara Üniversitesi Kimya Bölümü’nde lisans öğrenimini tamamladı. Yine aynı üniversitede yüksek lisans ve doktora öğrenimlerini tamamladı. Doktora eğitimi sırasında aynı zamanda araştırma görevlisi olarak çalışmaya başladı. 2017 yılında yardımcı doçent kadrosuna atanıp yine aynı yıl doçent ünvanını aldı. Işık ile sertleşen kaplama malzemeleri, alev geciktiriciler, poliüretan, poliimidler, nanomalzemeler ve biyobazlı polimerler çalışma konuları arasındadır. Üniversite-Sanayi işbirliği çerçevesinde çok sayıda projede bir çok şirkete danışmanlık yapmaktadır.
Burcu Oktay Marmara Üniversitesinde yüksek lisans ve doktora öğrenimlerini tamamladı. 2020 yılında doçent ünvanını aldı. Başlıca çalışma konuları arasında kontrollü polimerizasyon teknikleri, ışıkla sertleşen fonksiyonel kaplamalar, fonksiyonel enerji depolama malzemeleri, nanofiberler ve yüzey modifikasyonları yer almaktadır.
Managing editor
I have finished chemistry undergraduate in 1999 at Istanbul University Cerrahpasa and master of science education in 2002 at Istanbul University Cerrahpasa. After military service, I joined Istanbul Technical University in 2003 for PhD education, and finished in 2009, becoming official in 2010. I served the Chemistry Department until 2019, and moved to ITU Rectorate. Laboratory Coordination Unit and worked for a small time, then moved to ITU Library in January 2020. I worked there until 2022, when the ITU Publishing House was established. I have been working in there, specialized about in-house education and journal coordination and advisorship.
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1995-1999 İstanbul Üniversitesi Kimya Bölümü
1999-2002 İstanbul Üniversitesi Kimya ABD, Anorganik Kimya Programı
2003-2009 İstanbul Teknik Üniversitesi Kimya ABD, Anorganik Kimya Programı
1999-2002 İstanbul Üniversitesi Mühendislik Fakültesi Kimya bölümü, araştırma görevlisi
2005-2019 İstanbul Teknik Üniversitesi Fen-Edebiyat Fakültesi Kimya bölümü, uzman/öğretim görevlisi
2020-2022 İstanbul Teknik Üniversitesi Mustafa İnan Kütüphanesi
2023- İstanbul Teknik Üniversitesi Yayınevi
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Dr. Öğr. Üyesi Cemil Koyunoğlu; Enerji Sistemleri Mühendisliği ve Kimya Mühendisliği kesişiminde, özellikle biyokütle enerji sistemleri, yanma–gazlaştırma, termokimyasal dönüşüm süreçleri ve reaksiyon/taşınım temelli modelleme konularında çalışmaktadır. Araştırmaları, reaktör ve proses ölçeğinde verim–emisyon ilişkisini sayısal ve deneysel yaklaşımlarla açıklamaya; enerji sistemlerinde sürdürülebilirlik ve optimizasyon hedeflerine katkı sunmaya odaklanır.
Çalışmalarında, kömür/char yanma mekanizmalarında hız belirleyici (rate-determining) adımı temsil eden yeni bir yaklaşım olarak Cml (CML) denklemlerini kullanmakta ve geliştirmektedir. Bu çerçevede char yanma reaksiyon hızı; parçacık çapı ve yanma zamanı ilişkisinden türetilerek kütle-denge temelli hız ifadesiyle yazılmakta; örneğin tek parçacık için reaksiyon hızı
ifadesi Cml denklemi olarak verilmektedir. Bu yaklaşım, farklı parçacık boyutlarına göre sabit terimlerin belirlenmesiyle uygulamaya aktarılmaktadır.
Akademik çalışmalarının yanı sıra ulusal/uluslararası projelerde görev almakta; bilimsel dergilerde hakemlik ve editoryal süreçlerde aktif rol üstlenmektedir.
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Secretaries
İstanbul Üniversitesi Mühendislik Fakültesi Kimya bölümü Lisans (1995-1999)
İstanbul Üniversitesi Fen Bİlimleri Enstitüsü Kimya Anabilim Dalı Yüksek Lisans (1999-2002)
İstanbul Teknik Üniversitesi Fen Bilimleri Enstitüsü Kimya Anabilim Dalı Doktora (2003-2009)
İstanbul Üniversitesi Mühendislik Fakültesi Kimya Bölümü Araştırma Görevlisi (1999-2002)
İstanbul Teknik Üniversitesi Fen-Edebiyat Fakültesi Kimya Bölümü Uzman/Öğretim Görevlisi (2005-)
