Total Syntheses of Balsacone B and Balsacone C

Year 2017, Volume: 4 Issue: 3, 709 - 720, 05.07.2017

Serdar Burmaoğlu

https://doi.org/10.18596/jotcsa.311736

Cited By: 2

Abstract

The first total
syntheses of Balsacone C (16) and
Balsacone B (17), mainly based on a
convergent strategy, were described. The crucial step of this strategy was the
alkylation of trihydroxydihydrochalcone derivatives 7 and 8 with cinnamylbromide
derivative 13. For this, compounds 7 and 8 were prepared starting from trihydroxyacetophenone (1) in four steps. Then compound 13 was prepared starting from coumaric
acid (9) in four steps.      

Keywords

Synthesis , natural product , Balsacone B , Balsacone C

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