Bioactivity of Phaeophytin a, α-Amyrin and lupeol from Brachystelma togoense Schltr

Year 2019, Volume: 6 Issue: 3, 411 - 418, 20.10.2019

Abiche Ekalu , Rachael Gbekele-oluwa Ayo James Habila İbrahim Hamisu

https://doi.org/10.18596/jotcsa.571770

Cited By: 8

Abstract

Phaeophytin a, α-amyrin and
lupeol isolated from Brachystelma togoense were
screened against S. aureus, E. coli, S.
pneumonia, S. typhi, and C. albicans
using Ciprofloxacin and Terbinafine as standards.  The result showed that
these phytochemicals displayed antimicrobial activity against the tested
organisms with the zone of inhibition from 12 – 27 mm. The result of MIC showed
that Phaeophytin a was most active against C. albicans (0.09
mg/ml). The MBC showed that phaeophytin a and lupeol were
the most active against
S. aureus, S. pneumonia and S. typhi (0.37 mg/ml). The
result of MFC showed that
phaeophytin a was most active against C. albicans (0.1875
mg/ml).  The
activity of these phytoconstituents in B. togoense
justified ethnomedicinal uses of the plant. 

Keywords

Bioactivity, Phaeophytin a, α-amyrin and lupeol

Supporting Institution

TETFUND

Project Number

2017 Academic Training

Thanks

Thanks

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