Electrochemistry, DFT Calculations, and Antioxidant Capability of Cobalt Cefazolin Complex

Year 2022, Volume: 9 Issue: 4, 1083 - 1090, 30.11.2022

Elif Turker Acar

https://doi.org/10.18596/jotcsa.1171945

Abstract

The synthesis, characterization, electrochemistry, theoretical investigation and antioxidant capability of cobalt cefazolin [Co(Cefaz)Cl] complex are reported here. Electrochemical characterization of the complex was carried out by using cyclic voltammetry (CV) and Linear Sweep Voltammetry (LSV) methods. Two irreversible oxidative responses and one quasi-reversible reduction couple were observed for the complex on the voltammograms. The ground state energies of the molecules have been estimated using B3LYP functional with LanL2DZ basis set based on time dependent density functional theory (TD-DFT). According to the theoretical calculation, [Co(Cefaz)Cl] complex can be expected to exhibit greater reactivity from Cefazolin (Cefaz) ligand, and the higher antioxidant properties were observed for the complex. The experimental results are in good agreement with the theoretical calculations.

Keywords

cefazolin complex, electrochemistry, DFT calculation, antioxidant capability

Supporting Institution

The Scientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa

Project Number

35195

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