Research Article

Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients

Volume: 6 Number: 2 December 18, 2023
EN

Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients

Abstract

Dexamethasone is a synthetic adrenal corticosteroid with potent anti-inflammatory properties. Dexamethasone (MK-125) is a position 9 fluorinated corticosteroid used to treat endocrine, rheumatic, collagen, dermatological, allergic, ophthalmic, gastrointestinal, respiratory, hematological, neoplastic, edematous, and other conditions. On June 16, 2020, a press release for the Randomized Evaluation of COVID-19 Treatment (RECOVERY) trial recommended the use of dexamethasone in COVID-19 patients with severe respiratory symptoms. Dexamethasone reduced deaths by approximately one-third in ventilated patients and one-fifth in patients requiring oxygen. Therefore, Dexamethasone is used in the treatment of COVID-19 patients in some countries. In this study, we researched the spectroscopic and photonic properties of Dexamethasone. We have extensively studied the absorption spectra at different concentrations and their response to light. This study shows the absorbance spectra of the Dexamethasone for various concentrations. On the other hand, we continue to work intensively on some herbal suggestions that can be considered equivalent to Dexamethasone.

Keywords

References

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  6. Ahmed, M.H., Hassan, A. (2020) Dexamethasone for the Treatment of Coronavirus Disease (COVID-19): a Review. SN Compr. Clin. Med. 2, 2637–2646. https://doi.org/10.1007/s42399-020-00610-8.
  7. Águas, R., Mahdi, A., Shretta, R., Horby, P., Landray, M., White L., Consortium, T. C.M. (2021). Potential health and economic impacts of dexamethasone treatment for patients with COVID-19. Nat Commun 12, 915. https://doi.org/10.1038/s41467-021-21134-2.
  8. Tomazini, B.M., Maia, I.S., Cavalcanti, A.B., et al. Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial. JAMA. 2020;324(13):1307–1316. doi:10.1001/jama.2020.17021.

Details

Primary Language

English

Subjects

Metrology, Applied and Industrial Physics

Journal Section

Research Article

Publication Date

December 18, 2023

Submission Date

December 8, 2023

Acceptance Date

December 14, 2023

Published in Issue

Year 2023 Volume: 6 Number: 2

APA
Gündüz, B., & Buldurun, K. (2023). Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients. Journal of Physical Chemistry and Functional Materials, 6(2), 132-137. https://doi.org/10.54565/jphcfum.1402365
AMA
1.Gündüz B, Buldurun K. Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients. Journal of Physical Chemistry and Functional Materials. 2023;6(2):132-137. doi:10.54565/jphcfum.1402365
Chicago
Gündüz, Bayram, and Kenan Buldurun. 2023. “Spectroscopic and Photonic Properties of Dexamethasone Used in the Treatment of COVID-19 Patients”. Journal of Physical Chemistry and Functional Materials 6 (2): 132-37. https://doi.org/10.54565/jphcfum.1402365.
EndNote
Gündüz B, Buldurun K (December 1, 2023) Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients. Journal of Physical Chemistry and Functional Materials 6 2 132–137.
IEEE
[1]B. Gündüz and K. Buldurun, “Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients”, Journal of Physical Chemistry and Functional Materials, vol. 6, no. 2, pp. 132–137, Dec. 2023, doi: 10.54565/jphcfum.1402365.
ISNAD
Gündüz, Bayram - Buldurun, Kenan. “Spectroscopic and Photonic Properties of Dexamethasone Used in the Treatment of COVID-19 Patients”. Journal of Physical Chemistry and Functional Materials 6/2 (December 1, 2023): 132-137. https://doi.org/10.54565/jphcfum.1402365.
JAMA
1.Gündüz B, Buldurun K. Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients. Journal of Physical Chemistry and Functional Materials. 2023;6:132–137.
MLA
Gündüz, Bayram, and Kenan Buldurun. “Spectroscopic and Photonic Properties of Dexamethasone Used in the Treatment of COVID-19 Patients”. Journal of Physical Chemistry and Functional Materials, vol. 6, no. 2, Dec. 2023, pp. 132-7, doi:10.54565/jphcfum.1402365.
Vancouver
1.Bayram Gündüz, Kenan Buldurun. Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients. Journal of Physical Chemistry and Functional Materials. 2023 Dec. 1;6(2):132-7. doi:10.54565/jphcfum.1402365

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