MEDICAL AND BIOLOGICAL APPLICATIONS OF X-RAY FLUORESCENCE METHOD FOR ELEMENTAL ANALYSIS

Year 2018, Volume: 1 Issue: 2, 12 - 19, 30.11.2018

Sevil Porikli Durdağı

Abstract

X-ray fluorescence spectrometers use high energy
X-rays (or gamma rays) to excite fluorescent radiation from a sample for
quantitative chemical or elemental analysis and have many industrial and
research applications. XRF is primarily used as a non-destructive method for
investigation of metals, minerals, environmental samples, food constituents,
body fluids and biopsies. Microanalysis is the identification of the chemical
elements present either within or on the surface of an object, and
additionally, how the atoms of the elements are arranged with respect to each
other. Identification of the elements present may be qualitative or
quantitative. Techniques for estimation of element levels directly in humans
(noninvasive in vivo) or in samples (in vitro) from humans are reviewed. Toxic,
nonessential, trace elements may cause temporary or permanent damage to various
organs and tissues in humans. There is thus a need to control the
concentrations.In this work, we discuss applications in key areas with a view
to providing examples of how the technique can provide information on
biological and medical systems. Our goal is to provide useful and pertinent
information to encourage and enable further use of this powerful method in
chemical and biochemical studies.

Keywords

XRF, Microanalysis

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