Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta

Cengiz Sarıkürkçü; Mustafa Cengiz; Ahmet Küçükyumru; Gökhan Zengin

Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta

Abstract

The members of the genus Phlomis have been traditionally used for therapeutic purposes in Turkey. In this study, the antioxidant properties of different extracts from P. leucophracta were investigated. Antioxidant properties were evaluated by different assays including free radical scavenging (DPPH assay), reducing power (potassium ferricyanide method), β-carotene/linoleic acid, metal chelating and phosphomolybdenum. Moreover, total phenolic and flavonoid contents were detected for each extracts. Total phenolic and flavonoid contents were detected as 30.86-55.00 mg GAE/g extract and 4.93-26.09 mg QE/g extract, respectively. The methanol and water extracts exhibited higher DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging and reducing power abilities as compared to ethyl acetate and hexane extracts. The best activity was observed by the hexane extract in β-carotene/linoleic acid assay (94.35% at 2 mg/mL). In metal chelating ability, those samples exhibited the following order (at 0.25 mg/mL concentration): Water (73.90%)>Hexane(64.87%)>Ethyl acetate(4.88%)>Methanol (2.28%). Based on our results, P. leucophracta may be utilized as a natural source of antioxidant compounds in food and pharmaceutical areas.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmaceutical Analytical Chemistry, Pharmacognosy

Journal Section

Research Article

Authors

Cengiz Sarıkürkçü ^*
0000-0001-5094-2520
Türkiye

Mustafa Cengiz
Türkiye

Ahmet Küçükyumru This is me
Türkiye

Gökhan Zengin
0000-0001-6548-7823
Türkiye

Publication Date

June 27, 2025

Submission Date

August 29, 2017

Acceptance Date

September 20, 2017

Published in Issue

Year 2018 Volume: 22 Number: 1

IZ

https://izlik.org/JA56YD39GY

Cite

RIS / Bibtex

APA

Sarıkürkçü, C., Cengiz, M., Küçükyumru, A., & Zengin, G. (2025). Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta. Journal of Research in Pharmacy, 22(1), 86-90. https://izlik.org/JA56YD39GY

AMA

1.Sarıkürkçü C, Cengiz M, Küçükyumru A, Zengin G. Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta. J. Res. Pharm. 2025;22(1):86-90. https://izlik.org/JA56YD39GY

Chicago

Sarıkürkçü, Cengiz, Mustafa Cengiz, Ahmet Küçükyumru, and Gökhan Zengin. 2025. “Determination of Antioxidant Activities of Solvent Extracts from an Endemic Plant: Phlomis Leucophracta”. Journal of Research in Pharmacy 22 (1): 86-90. https://izlik.org/JA56YD39GY.

EndNote

Sarıkürkçü C, Cengiz M, Küçükyumru A, Zengin G (June 1, 2025) Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta. Journal of Research in Pharmacy 22 1 86–90.

IEEE

[1]C. Sarıkürkçü, M. Cengiz, A. Küçükyumru, and G. Zengin, “Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta”, J. Res. Pharm., vol. 22, no. 1, pp. 86–90, June 2025, [Online]. Available: https://izlik.org/JA56YD39GY

ISNAD

Sarıkürkçü, Cengiz - Cengiz, Mustafa - Küçükyumru, Ahmet - Zengin, Gökhan. “Determination of Antioxidant Activities of Solvent Extracts from an Endemic Plant: Phlomis Leucophracta”. Journal of Research in Pharmacy 22/1 (June 1, 2025): 86-90. https://izlik.org/JA56YD39GY.

JAMA

1.Sarıkürkçü C, Cengiz M, Küçükyumru A, Zengin G. Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta. J. Res. Pharm. 2025;22:86–90.

MLA

Sarıkürkçü, Cengiz, et al. “Determination of Antioxidant Activities of Solvent Extracts from an Endemic Plant: Phlomis Leucophracta”. Journal of Research in Pharmacy, vol. 22, no. 1, June 2025, pp. 86-90, https://izlik.org/JA56YD39GY.

Vancouver

1.Cengiz Sarıkürkçü, Mustafa Cengiz, Ahmet Küçükyumru, Gökhan Zengin. Determination of antioxidant activities of solvent extracts from an endemic plant: Phlomis leucophracta. J. Res. Pharm. [Internet]. 2025 Jun. 1;22(1):86-90. Available from: https://izlik.org/JA56YD39GY