Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice

Nur Hidayat Che Musa; Haniza Hanim Mohd Zain; Husni Ibrahim

Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice

Abstract

The study was conducted to investigate the effects of Aquilaria malaccensis leaves aqueous extracts on the aphrodisiac properties, which included; sexual behaviour, orientation activity, and testosterone level in ICR mice. Thirty healthy and sexually experienced male and thirty non-estrous female mice were used. In this experiment, each male was cohabitated with one female in a polysulfone cage. The mice were divided into 6 groups that received normal saline (control group), 50 mg/kg, 100 mg/kg, 200 mg/kg, 500 mg/kg, and 1000 mg/kg body weight of A. malaccensis leaves aqueous extract orally for 21 days consecutively. Results showed that all aphrodisiac parameters investigated in this study were similar between the treatment groups to the control group. However, two treated groups that received 100 mg/kg (day 14; day 21) and 200 mg/kg (day 0; day 21) resulted in significantly higher in mount frequency as compared to the control group. Overall, the results revealed that A. malaccensis leaves aqueous extract did not significantly alter the aphrodisiac parameters. Thus, this study validated that A. malaccensis leaves aqueous extracts lack of aphrodisiac properties in mice.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Research Article

Authors

Nur Hidayat Che Musa This is me
Malaysia

Haniza Hanim Mohd Zain ^* This is me
Malaysia

Husni Ibrahim This is me
Malaysia

Publication Date

June 27, 2025

Submission Date

February 22, 2018

Acceptance Date

May 24, 2018

Published in Issue

Year 2019 Volume: 23 Number: 1

IZ

https://izlik.org/JA39ES78KZ

Cite

RIS / Bibtex

APA

Che Musa, N. H., Mohd Zain, H. H., & Ibrahim, H. (2025). Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice. Journal of Research in Pharmacy, 23(1), 130-140. https://izlik.org/JA39ES78KZ

AMA

1.Che Musa NH, Mohd Zain HH, Ibrahim H. Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice. J. Res. Pharm. 2025;23(1):130-140. https://izlik.org/JA39ES78KZ

Chicago

Che Musa, Nur Hidayat, Haniza Hanim Mohd Zain, and Husni Ibrahim. 2025. “Aphrodisiac Properties of Aquilaria Malaccensis Leaves Aqueous Extract in ICR Mice”. Journal of Research in Pharmacy 23 (1): 130-40. https://izlik.org/JA39ES78KZ.

EndNote

Che Musa NH, Mohd Zain HH, Ibrahim H (June 1, 2025) Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice. Journal of Research in Pharmacy 23 1 130–140.

IEEE

[1]N. H. Che Musa, H. H. Mohd Zain, and H. Ibrahim, “Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice”, J. Res. Pharm., vol. 23, no. 1, pp. 130–140, June 2025, [Online]. Available: https://izlik.org/JA39ES78KZ

ISNAD

Che Musa, Nur Hidayat - Mohd Zain, Haniza Hanim - Ibrahim, Husni. “Aphrodisiac Properties of Aquilaria Malaccensis Leaves Aqueous Extract in ICR Mice”. Journal of Research in Pharmacy 23/1 (June 1, 2025): 130-140. https://izlik.org/JA39ES78KZ.

JAMA

1.Che Musa NH, Mohd Zain HH, Ibrahim H. Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice. J. Res. Pharm. 2025;23:130–140.

MLA

Che Musa, Nur Hidayat, et al. “Aphrodisiac Properties of Aquilaria Malaccensis Leaves Aqueous Extract in ICR Mice”. Journal of Research in Pharmacy, vol. 23, no. 1, June 2025, pp. 130-4, https://izlik.org/JA39ES78KZ.

Vancouver

1.Nur Hidayat Che Musa, Haniza Hanim Mohd Zain, Husni Ibrahim. Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice. J. Res. Pharm. [Internet]. 2025 Jun. 1;23(1):130-4. Available from: https://izlik.org/JA39ES78KZ