Electrochemical detection of anticancer drug lumazine and DNA interaction by using carbon nanotube modified electrodes

Year 2019, Volume: 23 Issue: 4, 682 - 688, 27.06.2025

Hakan Karadeniz , Ece Ekşin , Arzum Erdem

https://izlik.org/JA87TK98XR

Abstract

The interaction of lumazine (LMZ) with dsDNA was investigated with differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) by using disposable carbon nanotubes-modified pencil graphite electrode (CNTs-PGE). The passive adsorption process was used to modify the electrode surface by CNTs and then dsDNA was immobilized onto the modified PGEs. The performance of CNT-PGEs was studied by examining the optimum analytical conditions with DPV and then impedance method was performed to characterize the modification of CNTs onto the electrode surface.

Keywords

Biosensor , carbon nanotubes , electrochemistry , lumazine

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