Cytotoxicity screening of some Turkish plants against renal cancer cells

Feyyaz Mihoğlugil; Demet Akalgan; Fatma Tosun

Cytotoxicity screening of some Turkish plants against renal cancer cells

Abstract

In this contribution, we performed cytotoxicity screening of 51 extracts from 17 plant species, representing 14 families growing in Turkey. Cytotoxic activities of the dichloromethane, ethyl acetate, and methanol extracts of the plants were investigated against the renal (A498 and U031) cancer cell lines. 28 extracts exhibited more than 50% growth inhibition at a 25 ug/mL concentration on both renal cancer A498 and UO31 cell lines. The extracts showed higher activity against UO31 cells than A498 cells. The dichloromethane extract of the aerial parts of Scabiosa columbaria ssp. columbaria showed the highest cytotoxic activity with 64% inhibition at a 25 ug/mL concentration on the renal cancer UO31 cell line. The methanol extract of the aerial parts of Epilobium minutiflorum showed the highest cytotoxic activity with 63% inhibition at a 25 ug/mL concentration on the renal cancer A498 cell line.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Research Article

Authors

Feyyaz Mihoğlugil ^* This is me
0000-0003-0976-0244
Kuzey Kıbrıs Türk Cumhuriyeti

Demet Akalgan
0000-0001-6956-163X
Türkiye

Fatma Tosun
0000-0003-2533-5141
Türkiye

Publication Date

June 27, 2025

Submission Date

August 29, 2022

Acceptance Date

December 2, 2022

Published in Issue

Year 2023 Volume: 27 Number: 2

IZ

https://izlik.org/JA64ME78UT

Cite

RIS / Bibtex

APA

Mihoğlugil, F., Akalgan, D., & Tosun, F. (2025). Cytotoxicity screening of some Turkish plants against renal cancer cells. Journal of Research in Pharmacy, 27(2), 636-641. https://izlik.org/JA64ME78UT

AMA

1.Mihoğlugil F, Akalgan D, Tosun F. Cytotoxicity screening of some Turkish plants against renal cancer cells. J. Res. Pharm. 2025;27(2):636-641. https://izlik.org/JA64ME78UT

Chicago

Mihoğlugil, Feyyaz, Demet Akalgan, and Fatma Tosun. 2025. “Cytotoxicity Screening of Some Turkish Plants Against Renal Cancer Cells”. Journal of Research in Pharmacy 27 (2): 636-41. https://izlik.org/JA64ME78UT.

EndNote

Mihoğlugil F, Akalgan D, Tosun F (June 1, 2025) Cytotoxicity screening of some Turkish plants against renal cancer cells. Journal of Research in Pharmacy 27 2 636–641.

IEEE

[1]F. Mihoğlugil, D. Akalgan, and F. Tosun, “Cytotoxicity screening of some Turkish plants against renal cancer cells”, J. Res. Pharm., vol. 27, no. 2, pp. 636–641, June 2025, [Online]. Available: https://izlik.org/JA64ME78UT

ISNAD

Mihoğlugil, Feyyaz - Akalgan, Demet - Tosun, Fatma. “Cytotoxicity Screening of Some Turkish Plants Against Renal Cancer Cells”. Journal of Research in Pharmacy 27/2 (June 1, 2025): 636-641. https://izlik.org/JA64ME78UT.

JAMA

1.Mihoğlugil F, Akalgan D, Tosun F. Cytotoxicity screening of some Turkish plants against renal cancer cells. J. Res. Pharm. 2025;27:636–641.

MLA

Mihoğlugil, Feyyaz, et al. “Cytotoxicity Screening of Some Turkish Plants Against Renal Cancer Cells”. Journal of Research in Pharmacy, vol. 27, no. 2, June 2025, pp. 636-41, https://izlik.org/JA64ME78UT.

Vancouver

1.Feyyaz Mihoğlugil, Demet Akalgan, Fatma Tosun. Cytotoxicity screening of some Turkish plants against renal cancer cells. J. Res. Pharm. [Internet]. 2025 Jun. 1;27(2):636-41. Available from: https://izlik.org/JA64ME78UT