Research Article

Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale

Volume: 24 Number: 5 June 27, 2025
EN

Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale

Abstract

Knee osteoarthritis causes physical, functional limitations and difficulty in performing activities of daily living and mobility. The study aimed to assess patient-relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. A descriptive cross-sectional study was conducted on 120 patients. KOOS scale contains five subscales: pain, symptom, activities of daily living, sports/recreation, and quality of life. Score zero indicates the worst possible knee problems, while score 100 indicates no knee problems. Non-parametric tests, multiple linear regression analysis, and correlation were calculated for the data. The level of significance was p<0.05 and p<0.01. The mean age group of patients was 54.58±10.73 years. There was a statistically significant association observed between pain and disease duration (p=0.031); symptom and gender, comorbidities, and body mass index (p=0.038, 0.022, and 0.017, respectively); activities of daily living and knee surgery (p=0.043); sports/recreation and knee involved, disease duration (p=0.031, 0.033, respectively); and knee-related quality of life and gender (p=0.011). Knee surgery was an independent predictor for pain (p=0.008) and activities of daily living (p=0.008). There was a severe problem with sports/recreation in the patients. The knee-related quality of life was moderate. Knee surgery was found to be a strong independent predictor for pain and activities of daily living. However, socioeconomic status influenced the knee surgery in our patients.

Keywords

References

  1. [1] White DK, Tudor-Locke C, Zhang Y, Fielding R, LaValley M, Felson DT, Gross KD, Nevitt MC, Lewis CE, Torner J, Neogi T. Daily walking and the risk of incident functional limitation in knee osteoarthritis: an observational study. Arthritis Care Res (Hoboken). 2014;66(9);1328-1336. [CrossRef]
  2. [2] White DK, Lee J, Song J, Chang RW, Dunlop D. Potential functional benefit from light intensity physical activity in knee osteoarthritis. Am J Prev Med. 2017; 53(5):289-296. [CrossRef]
  3. [3] Dunlop DD, Song J, Lee J, Gilbert AL, Semanik PA, Ehrlich-Jones L, Pellegrini CA, Pinto D, Ainsworth B, Chang RW. Physical Activity Minimum Threshold Predicting Improved Function in Adults with Lower-Extremity Symptoms. Arthritis Care Res (Hoboken). 2017; 69(4): 475-483. [CrossRef]
  4. [4] Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, Bridgett L, Williams S, Guillemin F, Hill CL, Laslett LL, Jones G, Cicuttini F, Osborne R, Vos T, Buchbinder R, Woolf A, March L. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014; 73(7): 1323-1330. [CrossRef]
  5. [5] Pal CP, Singh P, Chaturvedi S, Pruthi KK, Vij A. Epidemiology of knee osteoarthritis in India and related factors. Indian J Orthop. 2016; 50(5): 518-522.
  6. [6] Evcik D, Sonel B. Effectiveness of a home-based exercise therapy and walking program on osteoarthritis of the knee. Rheumatol Int. 2002; 22(3):103-106. [CrossRef]
  7. [7] Sabirli F, Paker N, Bugdayci D. The relationship between Knee Injury and Osteoarthritis Outcome Score (KOOS) and Timed Up and Go test in patients with symptomatic knee osteoarthritis. Rheumatol Int. 2013; 33(10):2691-2694. [CrossRef]
  8. [8] Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD. Knee Injury and Osteoarthritis Outcome Score (KOOS)- development of a self-administered outcome measure. J Orthop Sports Phys Ther. 1998; 28(2):88-96. [CrossRef]

Details

Primary Language

English

Subjects

Pharmacology and Pharmaceutical Sciences (Other)

Journal Section

Research Article

Authors

Pujitha Kondru This is me
India

Sai Navya Manda This is me
India

Mahalakshmi Vegi This is me
India

Smruthi Kakada This is me
India

Publication Date

June 27, 2025

Submission Date

April 15, 2020

Acceptance Date

June 29, 2020

Published in Issue

Year 2020 Volume: 24 Number: 5

APA
Mugada, V., Kondru, P., Manda, S. N., Vegi, M., & Kakada, S. (2025). Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. Journal of Research in Pharmacy, 24(5), 786-792. https://doi.org/10.35333/jrp.2020.231
AMA
1.Mugada V, Kondru P, Manda SN, Vegi M, Kakada S. Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. J. Res. Pharm. 2025;24(5):786-792. doi:10.35333/jrp.2020.231
Chicago
Mugada, Vinodkumar, Pujitha Kondru, Sai Navya Manda, Mahalakshmi Vegi, and Smruthi Kakada. 2025. “Assessment of Patient Relevant Outcomes in Knee Osteoarthritis Patients Using the Knee Injury and Osteoarthritis Outcome Score (KOOS) Scale”. Journal of Research in Pharmacy 24 (5): 786-92. https://doi.org/10.35333/jrp.2020.231.
EndNote
Mugada V, Kondru P, Manda SN, Vegi M, Kakada S (June 1, 2025) Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. Journal of Research in Pharmacy 24 5 786–792.
IEEE
[1]V. Mugada, P. Kondru, S. N. Manda, M. Vegi, and S. Kakada, “Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale”, J. Res. Pharm., vol. 24, no. 5, pp. 786–792, June 2025, doi: 10.35333/jrp.2020.231.
ISNAD
Mugada, Vinodkumar - Kondru, Pujitha - Manda, Sai Navya - Vegi, Mahalakshmi - Kakada, Smruthi. “Assessment of Patient Relevant Outcomes in Knee Osteoarthritis Patients Using the Knee Injury and Osteoarthritis Outcome Score (KOOS) Scale”. Journal of Research in Pharmacy 24/5 (June 1, 2025): 786-792. https://doi.org/10.35333/jrp.2020.231.
JAMA
1.Mugada V, Kondru P, Manda SN, Vegi M, Kakada S. Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. J. Res. Pharm. 2025;24:786–792.
MLA
Mugada, Vinodkumar, et al. “Assessment of Patient Relevant Outcomes in Knee Osteoarthritis Patients Using the Knee Injury and Osteoarthritis Outcome Score (KOOS) Scale”. Journal of Research in Pharmacy, vol. 24, no. 5, June 2025, pp. 786-92, doi:10.35333/jrp.2020.231.
Vancouver
1.Vinodkumar Mugada, Pujitha Kondru, Sai Navya Manda, Mahalakshmi Vegi, Smruthi Kakada. Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. J. Res. Pharm. 2025 Jun. 1;24(5):786-92. doi:10.35333/jrp.2020.231