Research Article

The effect of calcium supplements on troponin variables in athletes and their association with bone diseases : Implications for myocardial health

Volume: 29 Number: 5 September 1, 2025
  • Muntadher Jaber *
  • Sada Ghalib Taher
  • Riyadh Rashid Hameed
  • Sajjad Mohammed Zorah
  • Doha Jehad Mohammad
  • Adyan Nafea Abbas
  • Falah Herez Madhloom Alrabea
  • Samer Kareem Hanoon
EN

The effect of calcium supplements on troponin variables in athletes and their association with bone diseases : Implications for myocardial health

Abstract

Calcium supplements are commonly used by athletes, and they are also used to treat certain bone ailments, however their cardiovascular safety is still debated. This study was designed to investigate the effect of calcium supplements on troponin variables in athletes as well as those with bone diseases. The current study is case control research included 180 participants (60 patients with bone problems, 60 athletes who use calcium supplements, and 60 healthy control subjects who do not take calcium supplements) and the levels of calcium and troponin measured for all subjected group. The results showed that serum calcium levels in athlete's participants were significantly higher than patients with bone diseases and healthy control subjects respectively (10.13 ± 1.2 vs 9.62 ± 0.92 and 8.57± 0.64, respectively). Also, the calcium levels in patients with bone diseases was significantly higher than healthy control subjects P< 0.001). Serum Troponine concentrations in patients with bone diseasesi and athletes participants were significantly higher than controls (0.22 ± 0.07 and 0.21 ± 0.07 vs 0.06 ± 0.01, respectively, P>0.001). Results showed that the Troponin levels correlate directly with serum calcium among study group which might be referred to that this condition enhances production of Troponin in relation to serum calcium which in turn affected by the calcium supplement administered that linked to a higher risk of myocardial infarction which lead to conclude that it is important to utilize calcium supplements sparingly and aim to get the majority of the necessary daily intake of calcium from food sources.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacology and Pharmaceutical Sciences (Other)

Journal Section

Research Article

Authors

Sada Ghalib Taher This is me
0000-0002-1685-6175
Iraq

Riyadh Rashid Hameed This is me
0009-0001-8021-3545
Iraq

Sajjad Mohammed Zorah This is me
0009-0006-3083-290X
Iraq

Doha Jehad Mohammad This is me
0009-0003-2518-9110
Iraq

Adyan Nafea Abbas This is me
0009-0002-9730-626X
Iraq

Falah Herez Madhloom Alrabea This is me
0000-0002-5224-2963
Iraq

Samer Kareem Hanoon This is me
0009-0005-5011-6217
Iraq

Publication Date

September 1, 2025

Submission Date

December 11, 2024

Acceptance Date

January 31, 2025

Published in Issue

Year 2025 Volume: 29 Number: 5

APA
Jaber, M., Taher, S. G., Hameed, R. R., Zorah, S. M., Mohammad, D. J., Abbas, A. N., Alrabea, F. H. M., & Hanoon, S. K. (2025). The effect of calcium supplements on troponin variables in athletes and their association with bone diseases : Implications for myocardial health. Journal of Research in Pharmacy, 29(5), 1890-1895. https://doi.org/10.12991/jrespharm.1763535
AMA
1.Jaber M, Taher SG, Hameed RR, et al. The effect of calcium supplements on troponin variables in athletes and their association with bone diseases : Implications for myocardial health. J. Res. Pharm. 2025;29(5):1890-1895. doi:10.12991/jrespharm.1763535
Chicago
Jaber, Muntadher, Sada Ghalib Taher, Riyadh Rashid Hameed, et al. 2025. “The Effect of Calcium Supplements on Troponin Variables in Athletes and Their Association With Bone Diseases : Implications for Myocardial Health”. Journal of Research in Pharmacy 29 (5): 1890-95. https://doi.org/10.12991/jrespharm.1763535.
EndNote
Jaber M, Taher SG, Hameed RR, Zorah SM, Mohammad DJ, Abbas AN, Alrabea FHM, Hanoon SK (September 1, 2025) The effect of calcium supplements on troponin variables in athletes and their association with bone diseases : Implications for myocardial health. Journal of Research in Pharmacy 29 5 1890–1895.
IEEE
[1]M. Jaber et al., “The effect of calcium supplements on troponin variables in athletes and their association with bone diseases : Implications for myocardial health”, J. Res. Pharm., vol. 29, no. 5, pp. 1890–1895, Sept. 2025, doi: 10.12991/jrespharm.1763535.
ISNAD
Jaber, Muntadher - Taher, Sada Ghalib - Hameed, Riyadh Rashid - Zorah, Sajjad Mohammed - Mohammad, Doha Jehad - Abbas, Adyan Nafea - Alrabea, Falah Herez Madhloom - Hanoon, Samer Kareem. “The Effect of Calcium Supplements on Troponin Variables in Athletes and Their Association With Bone Diseases : Implications for Myocardial Health”. Journal of Research in Pharmacy 29/5 (September 1, 2025): 1890-1895. https://doi.org/10.12991/jrespharm.1763535.
JAMA
1.Jaber M, Taher SG, Hameed RR, Zorah SM, Mohammad DJ, Abbas AN, Alrabea FHM, Hanoon SK. The effect of calcium supplements on troponin variables in athletes and their association with bone diseases : Implications for myocardial health. J. Res. Pharm. 2025;29:1890–1895.
MLA
Jaber, Muntadher, et al. “The Effect of Calcium Supplements on Troponin Variables in Athletes and Their Association With Bone Diseases : Implications for Myocardial Health”. Journal of Research in Pharmacy, vol. 29, no. 5, Sept. 2025, pp. 1890-5, doi:10.12991/jrespharm.1763535.
Vancouver
1.Muntadher Jaber, Sada Ghalib Taher, Riyadh Rashid Hameed, Sajjad Mohammed Zorah, Doha Jehad Mohammad, Adyan Nafea Abbas, Falah Herez Madhloom Alrabea, Samer Kareem Hanoon. The effect of calcium supplements on troponin variables in athletes and their association with bone diseases : Implications for myocardial health. J. Res. Pharm. 2025 Sep. 1;29(5):1890-5. doi:10.12991/jrespharm.1763535