Knowledge, attitude, and perception of Libyan pharmacists towards pharmacogenomics services: A cross sectional prospective study

Year 2025, Volume: 29 Issue: 4, 1507 - 1515, 05.07.2025

Khalid A. Mohamad , Hiba A. Alshami Maryam S.e. Hussein Nouha E. El Shnitri

https://doi.org/10.12991/jrespharm.1734615

Abstract

Pharmacogenomics is the study of how person's genes affect their response to drugs and could be used to personalize drug therapy and improve patient outcomes. Pharmacists are increasingly involved in the application of Pharmacogenomics services, as they are well-positioned to educate patients about their genetic risks and help them select the best medications for their individual needs. To evaluate the knowledge, attitude, and perception of Libyan pharmacists towards Pharmacogenomics services, a cross-sectional study was conducted among pharmacists in Libya using a validated, pilot-tested, and self-administered online questionnaire between August 2023 and September 2023. Descriptive statistics and multivariate logistic regression models were used to describe the results of the study. Most of the participants were female (73%), community pharmacists (56%), and from the eastern part of Libya (73.8%). The respondents have a low knowledge score in Pharmacogenomics and 75.2% of them expressed interest in attending Pharmacogenomics training in the future. Additionally, the participants showed positive attitude and perception towards Pharmacogenomics services (total mean attitude score = 2.9 out of 4 and total median perception score = 32.0 out of 35). They agreed upon barriers for the implementation the Pharmacogenomics services, such as were lack of reimbursement, knowledge, and guidelines. Overall, the survey revealed that pharmacists are interested in learning more about Pharmacogenomics and are positive about the potential benefits of this technology. Despite the low knowledge of pharmacists in Pharmacogenomics, they showed a positive attitude and perception. Therefore, there is a high need for training and improving the Pharmacy curriculum by involving more Pharmacogenomics courses to ensure the proper application of Pharmacogenomics.

Keywords

Knowledge , attitude , perception , pharmacogenomics , pharmacists , Libya

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