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Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes)

Year 2025, Volume: 44 Issue: 1, 66 - 69, 29.07.2025

Abstract

Chimpanzees are long-lived social animals with close phylogenetic traits to humans and they also require great opportunity for social interactions, care and management even in captivity. Thus like humans, they are faced with challenges of wounding, although with higher frequency in captivity than their counterparts in the wild. Clinical examination of complete blood counts and serum biochemistry as in other non-human primates (NHP) and human is vital for improved management and monitoring. In late 2023, the attention of the Veterinary Teaching Hospital, wildlife unit, University of Jos was drawn to a wounded adult female Chimpanzee at the Jos Zoo, Plateau state, Nigeria. It was reported to have occurred following a fight with a younger male in the shelter. Clinical examination revealed varying degree of injuries on the left index, middle and ring fingers with traumatic amputation of portions of the index and ring fingers. Following immobilization using ketamine and xylazine (12mg/kg and 0.2mg/kg body weight), 5 milliliter of blood was collected via femoral venipuncture pre- and post-operative management for haemato-biochemical profiling. All parameters were largely within normal reference limits, except for a moderate hypoproteinemia. A shift from chronicity following the instituted management resulted in observed progressive healing of the wounds. Total protein, conjugated bilirubin, high density lipids and low density lipids obtained in this study could be adopted as guide for subsequent investigation involving the liver and fasting lipids. In conclusion, the haemato-biochemical profile in this report may be important in managing wounded Chimpanzees as values may be influenced by the individual’s dynamic pathophysiological state.

References

  • Stone GA, Johnson BK, Druilhet R, Garza PB, Gibbs CJ. Immunophenotyping of peripheral blood, ranges of serum chemistries and clinical hematology values of healthy chimpanzees (Pan troglodytes). J. Med. Primatol. 2000; 29:324-329.
  • Ross SR, Joshi PB, Terio KA, Gamble KC. A 25-Year Retrospective Review of Mortality in Chimpanzees (Pan troglodytes) in Accredited U.S. Zoos from a Management and Welfare Perspective. J. Anim. 2022; 12:1878-1890.
  • Fultz A, Yanagi A, Breaux S, Beaupre L. Aggressive, Submissive, and Affiliative Behavior in Sanctuary Chimpanzees (Pan troglodytes) during Social Integration. J. Anim. 2022; 12:2421-2444.
  • Borena BM, Martens A, Broeckx SY, et al. Regenerative skin wound healing in mammals: State-of-the-art on growth factor and stem cell based treatments. Cell. Physiol. Biochem. 2015; 36(1):1-23.
  • Granat FA, Trumel C, Braun JP, Bourgès-Abella NH. Quality of hematology and clinical chemistry results in laboratory and zoo nonhuman primates: Effects of the preanalytical phase. A review. J. Med. Primatol. 2023; 52: 414–427.
  • Da Silva GP, Pereira THS, De JT, et al. Hematological and serum biochemistry evaluation in howler monkeys (Alouatta caraya) and capuchin monkeys (Sapajus apella): A comparative study. J. Med. Primatol. 2023; 52(3):170–185.
  • Wilcox AL, Siska W, Poitout-Belissent FM. Spontaneous Pathology of the Laboratory Non-Human Primate. In: Chapter 21 - Clinical pathology of the non-human primate, Editor(s): Bradley AE, Chilton JA, Mahler BW. Academic Press. 2023. p. 525 – 552.
  • Hernández-Cruz G, Ferreira RG, Rooney NJ, et al. Haematology, physiological parameters, morphometry and parasitological status of rescued bearded capuchin monkeys (Sapajus libidinosus). J. Med. Primatol. 2022; 51(4): 213–222.
  • Howell S, Hoffman K, Bartel L, Schwandt M, Morris J, Fritz J. Normal Hematologic and Serum Clinical Chemistry Values for Captive Chimpanzees (Pan troglodytes) Comp Med. 2003; 53(4):413–423.
  • Ihrig M, Tassinary L G, Bernacky B, Keeling ME. Hematologic and serum biochemical reference intervals for the chimpanzee (Pan troglodytes) categorized by age and sex. Comp. med 2001; 51(1), 30-37.
  • Avazi DO, Awasum CA, Hassan AZ, et al. Evaluation of levels of interleukin-6, interleukin-8 and some haematologic parameters of dogs with cutaneous wounds. Cytokine, 2019; 113: 128-138.
  • Witte MB, Barbul A. General principles of wound healing. Surg. Clin. North Am. 1997; 77(3): 509–528. In: Park JE, Barbul A. Understanding the role of immune regulation in wound healing. Am. J. Surg. 2004; 187(Suppl to May 2004): 11S–16S.

Year 2025, Volume: 44 Issue: 1, 66 - 69, 29.07.2025

Abstract

References

  • Stone GA, Johnson BK, Druilhet R, Garza PB, Gibbs CJ. Immunophenotyping of peripheral blood, ranges of serum chemistries and clinical hematology values of healthy chimpanzees (Pan troglodytes). J. Med. Primatol. 2000; 29:324-329.
  • Ross SR, Joshi PB, Terio KA, Gamble KC. A 25-Year Retrospective Review of Mortality in Chimpanzees (Pan troglodytes) in Accredited U.S. Zoos from a Management and Welfare Perspective. J. Anim. 2022; 12:1878-1890.
  • Fultz A, Yanagi A, Breaux S, Beaupre L. Aggressive, Submissive, and Affiliative Behavior in Sanctuary Chimpanzees (Pan troglodytes) during Social Integration. J. Anim. 2022; 12:2421-2444.
  • Borena BM, Martens A, Broeckx SY, et al. Regenerative skin wound healing in mammals: State-of-the-art on growth factor and stem cell based treatments. Cell. Physiol. Biochem. 2015; 36(1):1-23.
  • Granat FA, Trumel C, Braun JP, Bourgès-Abella NH. Quality of hematology and clinical chemistry results in laboratory and zoo nonhuman primates: Effects of the preanalytical phase. A review. J. Med. Primatol. 2023; 52: 414–427.
  • Da Silva GP, Pereira THS, De JT, et al. Hematological and serum biochemistry evaluation in howler monkeys (Alouatta caraya) and capuchin monkeys (Sapajus apella): A comparative study. J. Med. Primatol. 2023; 52(3):170–185.
  • Wilcox AL, Siska W, Poitout-Belissent FM. Spontaneous Pathology of the Laboratory Non-Human Primate. In: Chapter 21 - Clinical pathology of the non-human primate, Editor(s): Bradley AE, Chilton JA, Mahler BW. Academic Press. 2023. p. 525 – 552.
  • Hernández-Cruz G, Ferreira RG, Rooney NJ, et al. Haematology, physiological parameters, morphometry and parasitological status of rescued bearded capuchin monkeys (Sapajus libidinosus). J. Med. Primatol. 2022; 51(4): 213–222.
  • Howell S, Hoffman K, Bartel L, Schwandt M, Morris J, Fritz J. Normal Hematologic and Serum Clinical Chemistry Values for Captive Chimpanzees (Pan troglodytes) Comp Med. 2003; 53(4):413–423.
  • Ihrig M, Tassinary L G, Bernacky B, Keeling ME. Hematologic and serum biochemical reference intervals for the chimpanzee (Pan troglodytes) categorized by age and sex. Comp. med 2001; 51(1), 30-37.
  • Avazi DO, Awasum CA, Hassan AZ, et al. Evaluation of levels of interleukin-6, interleukin-8 and some haematologic parameters of dogs with cutaneous wounds. Cytokine, 2019; 113: 128-138.
  • Witte MB, Barbul A. General principles of wound healing. Surg. Clin. North Am. 1997; 77(3): 509–528. In: Park JE, Barbul A. Understanding the role of immune regulation in wound healing. Am. J. Surg. 2004; 187(Suppl to May 2004): 11S–16S.
There are 12 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery, Veterinary Sciences (Other)
Journal Section Case Reports
Authors

Daniel Avazi 0000-0002-4940-671X

Promise Okoro 0009-0009-9167-9808

Uchenna Nnadi 0000-0001-8780-8464

Polycarp Tanko 0000-0003-1459-2564

Publication Date July 29, 2025
Submission Date February 28, 2024
Acceptance Date March 4, 2025
Published in Issue Year 2025 Volume: 44 Issue: 1

Cite

APA Avazi, D., Okoro, P., Nnadi, U., Tanko, P. (2025). Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes). Journal of Research in Veterinary Medicine, 44(1), 66-69.
AMA Avazi D, Okoro P, Nnadi U, Tanko P. Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes). J Res Vet Med. July 2025;44(1):66-69.
Chicago Avazi, Daniel, Promise Okoro, Uchenna Nnadi, and Polycarp Tanko. “Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes)”. Journal of Research in Veterinary Medicine 44, no. 1 (July 2025): 66-69.
EndNote Avazi D, Okoro P, Nnadi U, Tanko P (July 1, 2025) Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes). Journal of Research in Veterinary Medicine 44 1 66–69.
IEEE D. Avazi, P. Okoro, U. Nnadi, and P. Tanko, “Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes)”, J Res Vet Med, vol. 44, no. 1, pp. 66–69, 2025.
ISNAD Avazi, Daniel et al. “Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes)”. Journal of Research in Veterinary Medicine 44/1 (July2025), 66-69.
JAMA Avazi D, Okoro P, Nnadi U, Tanko P. Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes). J Res Vet Med. 2025;44:66–69.
MLA Avazi, Daniel et al. “Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes)”. Journal of Research in Veterinary Medicine, vol. 44, no. 1, 2025, pp. 66-69.
Vancouver Avazi D, Okoro P, Nnadi U, Tanko P. Haemato-Biochemıcal Profile Of A Wounded Captive Adult Female Chimpanzee (Pan Troglodytes). J Res Vet Med. 2025;44(1):66-9.