Research Article

Use of laboratory parameters in the differential diagnosis of ovarian cyst rupture and acute appendicitis

Volume: 16 Number: 2 August 8, 2023
TR EN

Use of laboratory parameters in the differential diagnosis of ovarian cyst rupture and acute appendicitis

Abstract

The study aimed to analyze the diagnostic power of laboratory parameters in the differential diagnosis of acute appendicitis and ovarian cyst rupture originating from the right lower quadrant in female patients presenting to the emergency department with right lower quadrant pain. Between 2016 and 2021, 200 female patients who presented to the emergency department with acute right lower quadrant pain and were diagnosed with acute appendicitis or ovarian cyst rupture by abdominal tomography and post-operative pathology results were included in the study. Laboratory parameters of the patients were analyzed. The role of the obtained results in the differential diagnosis was investigated. The diagnoses of acute appendicitis and ovarian cyst rupture were randomized 1:1 for the female patients included in the study. The groups were modeled to have similar demographic characteristics. Neutrophil, lymphocyte, leukocyte, leukocyte, MPV, platelet, and CRP values were analyzed. Neutrophil/lymphocyte and platelet/lymphocyte ratios were calculated. Inflammation parameters, N/L, and P/L ratios were significantly higher in patients with acute appendicitis. High inflammation findings shown by laboratory data support acute appendicitis. Patients with acute appendicitis have a stronger inflammatory reaction. High inflammatory markers are interpreted in favor of appendicitis. Laboratory parameters facilitate clinical decision-making and support the preliminary diagnosis in the differential diagnosis of female patients presenting to the emergency department with right lower quadrant pain.

Keywords

References

  1. 1. Di Saverio S, Podda M, De Simone B, et al. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines. World J Emerg Surg 2020;15:27-33.
  2. 2. Cervellin G, Mora R, Ticinesi A, et al. Epidemio-logy and outcomes of acute abdominal pain in a large urban Emergency Department: retros-pective analysis of 5,340 cases. Ann Transl Med. 2016;4:362.
  3. 3. Andersson RE. Meta-analysis of the clinical and laboratory diagnosis of appendicitis. British J Surg 2004;91(1):28-37.
  4. 4. Flum DR, Koepsell TD. Evaluating diagnostic accuracy in appendicitis using administrative data. J Surg Res 2005;123:257-261.
  5. 5. Pegoli W. Acute appendicitis. In: Cameron JL (ed). Current surgical therapy. 6th Edition. St Louis: Mosby, 1998. Pp:263-266.
  6. 6. Colson M, Skinner KA, Dunnington G. High negative appendectomy rates are no longer ac-ceptable. Am J Surg 1997;174:723-726; discus-sion 726-727.
  7. 7. Fingerhut A, Yahchouchy-Chouillard E, Etienne JC, Ghiles E. Appendicitis or non-specific pain in the right iliac fossa? Rev Prat 2001;51:1654-1656.
  8. 8. Hallan S, Asberg A, Edna TH. Additional value of biochemical tests in suspected acute appen-dicitis. Eur J Surg 1997;163:533-538.

Details

Primary Language

English

Subjects

General Surgery, Surgery (Other)

Journal Section

Research Article

Publication Date

August 8, 2023

Submission Date

July 6, 2023

Acceptance Date

July 31, 2023

Published in Issue

Year 2023 Volume: 16 Number: 2

APA
Kardaş, S., Ermete Güler, E., Payza, U., Kayalı, A., Efgan, M. G., & Çınaroğlu, O. S. (2023). Use of laboratory parameters in the differential diagnosis of ovarian cyst rupture and acute appendicitis. Journal of Surgical Arts, 16(2), 30-34. https://izlik.org/JA48RU68CH
AMA
1.Kardaş S, Ermete Güler E, Payza U, Kayalı A, Efgan MG, Çınaroğlu OS. Use of laboratory parameters in the differential diagnosis of ovarian cyst rupture and acute appendicitis. JSurgArts. 2023;16(2):30-34. https://izlik.org/JA48RU68CH
Chicago
Kardaş, Süleyman, Ecem Ermete Güler, Umut Payza, Ahmet Kayalı, Mehmet Göktuğ Efgan, and Osman Sezer Çınaroğlu. 2023. “Use of Laboratory Parameters in the Differential Diagnosis of Ovarian Cyst Rupture and Acute Appendicitis”. Journal of Surgical Arts 16 (2): 30-34. https://izlik.org/JA48RU68CH.
EndNote
Kardaş S, Ermete Güler E, Payza U, Kayalı A, Efgan MG, Çınaroğlu OS (August 1, 2023) Use of laboratory parameters in the differential diagnosis of ovarian cyst rupture and acute appendicitis. Journal of Surgical Arts 16 2 30–34.
IEEE
[1]S. Kardaş, E. Ermete Güler, U. Payza, A. Kayalı, M. G. Efgan, and O. S. Çınaroğlu, “Use of laboratory parameters in the differential diagnosis of ovarian cyst rupture and acute appendicitis”, JSurgArts, vol. 16, no. 2, pp. 30–34, Aug. 2023, [Online]. Available: https://izlik.org/JA48RU68CH
ISNAD
Kardaş, Süleyman - Ermete Güler, Ecem - Payza, Umut - Kayalı, Ahmet - Efgan, Mehmet Göktuğ - Çınaroğlu, Osman Sezer. “Use of Laboratory Parameters in the Differential Diagnosis of Ovarian Cyst Rupture and Acute Appendicitis”. Journal of Surgical Arts 16/2 (August 1, 2023): 30-34. https://izlik.org/JA48RU68CH.
JAMA
1.Kardaş S, Ermete Güler E, Payza U, Kayalı A, Efgan MG, Çınaroğlu OS. Use of laboratory parameters in the differential diagnosis of ovarian cyst rupture and acute appendicitis. JSurgArts. 2023;16:30–34.
MLA
Kardaş, Süleyman, et al. “Use of Laboratory Parameters in the Differential Diagnosis of Ovarian Cyst Rupture and Acute Appendicitis”. Journal of Surgical Arts, vol. 16, no. 2, Aug. 2023, pp. 30-34, https://izlik.org/JA48RU68CH.
Vancouver
1.Süleyman Kardaş, Ecem Ermete Güler, Umut Payza, Ahmet Kayalı, Mehmet Göktuğ Efgan, Osman Sezer Çınaroğlu. Use of laboratory parameters in the differential diagnosis of ovarian cyst rupture and acute appendicitis. JSurgArts [Internet]. 2023 Aug. 1;16(2):30-4. Available from: https://izlik.org/JA48RU68CH

The Journal of Surgical Arts (ISSN: 1308-0709) is included in or indexed in the following databases: OJS/PKP, CROSSREF, EBSCO Host, Google Scholar, CiteFactor, MIAR Index, EuroPub Database, CABELLS, Dergipark (TUBITAK), Turkish Citation Index, Sobiad, Asos Index, İdeal Index, and Akademik Index.

Note: The Journal of Surgical Arts is among the journals indexed by international databases (OJS/PKP, EBSCO, etc.) as defined by the "Interuniversity Council" (YÖK, Turkey).

Submission: When submitting your article, you will be redirected to DergiPark (Journal of Surgical Arts » Homepage (dergipark.org.tr)), the hosting and article tracking service provider. You can easily log in with your chosen username and password.