The Virchow theory defined at the beginning of the 19th century is still valid in etiology of venous thromboembolism. According to this theory, stasis, damage to the vein walls and hypercoagulation of blood are the three main contributing factors of the disease. One of this contributing factors alone is effective in increasing the risk of venous thromboembolism formation. The targets of the treatment are to prevent lung emboly, to stop the progression of thrombosis, to reperfuse and recanalise the thrombosed veins, to prevent post-thrombophlebitic syndrome and recurrences of thrombosis and to prevent pulmonary hypertension. In venous thromboembolism, prophylaxy is applied to patients of high risk to prevent vein thrombosis and pulmonary embolism. VTE etiology can divided into three groups whicih are; 30% malignities, 30% hospitali-sation and 40% idiopatic. Venous thromboembolism or commonly known as deep venous thrombosis (DVT) is an important cause of mortality and mor-bidity. VTE is a condition, which can be prevented by different prophylactic measures. Here, we reviewed the risk factors, incidence and prophylactic measures in surgical and medical patients in view of the literature.
Venöz tromboembolizmin etyopatogenezi 19. Yüzyılda Wirchow tarafından bildirilmiş olup günümüzde de halen geçerliliğini korumaktadır. Bu teoriye göre venöz trombus oluşumuna neden olan faktörler; staz, venöz endotel hasarı, ve hiperkoagulabilitedir. Venöz tromboemboli oluşumunda bu faktörlerden bir tanesinin olması yeterlidir. Venöz tromboemboli tedavisinde amaç pulmoner emboli gelişimini önlemek, trombus büyümesini önlemek ve venöz trombus rekanalizasyonu erken dönemde sağlayarak post-tromboflebitik sendrom, tromboz rekurrensini ve pulmoner emboliler sonucu pulmoner hipertansiyon gelişimini önlemektir. Venöz tromboembolizm veya en sık görülen formuyla derin ven trombozu (DVT) önemli bir mortalite ve morbidite nedenidir. VTE risk faktörleri düşünüldüğünde profilaktik yöntemlerle önlenebilecek bir durumdur. Bu yazıda cerrahi ve dahiliye kliniklerinde yatan hastalardaki risk faktörlerini, VTE insidansını ve profilaksisini literatür bilgileri ışığında değerlendirdik.
Other ID | JA83PR79UU |
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Journal Section | Research Article |
Authors | |
Publication Date | June 1, 2008 |
Submission Date | June 1, 2008 |
Published in Issue | Year 2008 Volume: 1 Issue: 2 |
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