Primer yüzük hücreli karsinomlar safrakesesinin nadir görülen ve agressif seyreden tümörleridir. Şimdiye kadar literatürde bildirilen vaka sayısı çok azdır. Burada nonspesifik semptomlarla karşımıza çıkan, ultrasonografide safrakesesinde polipoid kitle tesbit edilen, 54 yaşındaki bir erkek hastamızı sunduk. Hastaya radikal cerrahi ve kemoterapi uygulandı. Tanıda benign veya malign olup olmadığı konusunda karışıklık meydana gelebilir, hatta inflamatuar hücrelerle karıştırılabilir. Erken tanı için öncelikle şüphelenilebilmeli ve alınacak biyopsi örneklerinde asit Schiff ve immünhistokimyasal veriler tanıya yardımcı olabilir. Radikal cerrahi ve takiben kemoterapi yapılan hastamız metastazsız olarak yaşamını sürdürmektedir.
Primary signet ring cell carcinoma is a rare and aggressive neoplasm of the gall bladder. Only few cases of this type have been reported till date and detailed knowledge about this entity is lacking. Signet ring cell carcinoma in a 54 year old man is reported here. He presented with non specific symptoms of upper abdominal pain and anorexia. Ultrasonography revealed a polypoid mass in the body of gall bladder. The diagnosis can be confused with non-neoplastic benign signet ring cells. However the benign signet ring cells do not encompass full thickness of the wall and are associated with inflammatory cells. An early diagnosis with the help of imaging study and special stains on the biopsy specimen like periodic acid Schiff and immunohistochemistry can help in patient survival. Radical surgery was done and chemotherapy given. Presently the patient is under follow up without obvious metastasis.
Other ID | JA82DP57HE |
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Journal Section | Case Report |
Authors | |
Publication Date | March 1, 2014 |
Submission Date | March 1, 2014 |
Published in Issue | Year 2014 Volume: 7 Issue: 1 |
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