Gastrointestinal stromal tumors (GISTs) are uncommon neoplasms but comprise of the most common mesenchymal tumors of the gastrointestinal tract. Depending on the site of the tumor, the clinical manifestations vary considerably. GISTs arising from the stomach may sometimes pose a challenge for diagnosis to the clinician. Here we report a case of GIST presenting as a painless gradually increasing intra-abdominal lump in a 65-year-old female patient that was initially diagnosed as retroperitoneal sarcoma by ultrasonography and contrast-enhanced computed tomography. Fine needle aspiration cytology of the mass revealed spindle cells with plump nuclei suggestive of GIST. Exploratory laparotomy showed that the lump was a large variegated mass occupying the left hypochondrium, epigastrium, umbilical and left lumbar regions. Histopathology studies showed highly cellular morphology with spindle cells along with myxoid changes and areas of hemorrhage and necrosis, leading to a diagnosis of a high grade GIST arising from the stomach.
Gastrointestinal stromal tümörler (GİST), gastrointestinal sistemde karşılaşılan mezankimal tümörler olup nadir görülen lezyonlardır. Tümörün yerine bağlı olarak klinik belirtileri değişiklikler gösterir. Mide menşeyli GİST’ler zaman zaman klinisyenlerin ayırıcı tanısında sözkonusu olur. Bu makalede 65 yaşındaki bir kadın hastada ultrasonografik olarak ve kontrastlı tomografi ile başlangıçta retroperitoneal sarkom olarak tanımlanan bir GİST olgusu sunuldu. İnce iğne aspirasyon biyopsisi ile iğ şekilli ve dolgun nükleuslar içeren GİST tanısı konuldu. Yapılan tanısal laparotomide sol hipokondrium, ve epigastriumu dolduran büyük kitle saptandı. Histopatolojik çalışmalar sonucunda, bol miktarda iğsi hücre morfoloji ve miksoid değişiklik, hemoraji ve nekroz varlığı ilemide kaynaklı yüksek dereceli GİST tanısı konuldu.
Other ID | JA24MN82PS |
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Journal Section | Case Report |
Authors | |
Publication Date | March 1, 2015 |
Submission Date | March 1, 2015 |
Published in Issue | Year 2015 Volume: 8 Issue: 1 |
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