Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Initial experience in a low volume center

Year 2018, Volume: 11 Issue: 2, 34 - 38, 11.07.2018

Bülent Kaya

Abstract

Keywords

Peritoneal karsinomatoz, sitoredüktif cerrahi, hipertermik intraperitoneal kemote, hipertermik intraperitoneal kemoterapi (HIPEK), hipertermik intraperitoneal kemote

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Initial experience in a low volume center

Abstract

Peritoneal carcinomatosis (PC) is defined as tumoral lesions located on peritoneal surface. In this study, we examined demographic findings, operational findings, early and late postoperative complications and survival times of our patients who underwent CRC + HIPEC due to PC.
Between January 2013 to September 2017 patients operated due to gynecological, gastrointestinal PC or primary peritoneal mesothelioma were studied retrospectively. CRS+HIPEC was performed for treatment of PC.
Demographic characteristics of patients, preoperative and intraoperative findings, postoperative early and late complications, and survival times were evaluated. Statistical analysis was performed. Median follow-up and overall survival were calculated from the date of surgery until death, or last follow-up visit.
A total of 6 women (75%) and 2 men (25%) aged between 40-75 years (mean age 54.3 years) were operated due to PC secondary to ovarian cancer, gastric cancer, colon cancer, or due to primary mesothelioma. Two patients developed morbidity at the postoperative period including pleural effusion, intraabdominal abscess, sepsis, wound dehiscence. Two patients were died in early period due to recurrence.
This study presents outcomes of a very limited number of cases. CRC+HIPEC can be performed in a low volume center in selected patients with CC0 or CC1 resections.

Keywords

Peritoneal karsinomatoz, sitoredüktif cerrahi, hipertermik intraperitoneal kemoterapi