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Liver and kidney transplantation as treatments for type 1 primary hyperoxaluria

Year 2019, Volume: 12 Issue: 2, 28 - 31, 01.07.2019

Abstract

Type 1 primary hyperoxaluria is an autosomal, recessive metabolic disease triggering calcium oxalate accumulation in tissues. The liver lacks the peroxisomal enzyme alanine-glyoxylate amino transferase. Clinically, patients develop kidney stones, urinary tract infections, and progressive renal failure. We evaluated liver and kidney transplantation to performed for type 1 primary hyperoxaluria in our study.
In this study, we retrospectively evaluated 7 patients with type 1 primary hyperoxaluria who underwent liver and kidney transplantation. Two main groups were established; Sequential and simultaneous liver and kidney transplantation group. Mortality rates were compared between these two groups.
Sequential liver and kidney transplantation was performed in 5 (71.4%) patients and simultaneous liver and kidney transplantation was performed in 2 (28.6%) patients. All patients died in simultaneous liver and kidney transplantation group.
Sequential liver and kidney transplantation group mortality rates were lower therefore treatment for type 1 primary hyperoxaluria more preferable.

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Details

Primary Language English
Subjects Surgery
Journal Section Research Article
Authors

Gökhan Ertuğrul This is me

Publication Date July 1, 2019
Submission Date February 6, 2019
Published in Issue Year 2019 Volume: 12 Issue: 2

Cite

Vancouver Ertuğrul G. Liver and kidney transplantation as treatments for type 1 primary hyperoxaluria. JSurgArts. 2019;12(2):28-31.

Journal of Surgical Arts (Cerrahi Sanatlar Dergisi, ISSN:1308-0709) is indexed with, or included in, the following;  OJS, DOAJ, CROSSREF, EBSCO Host, Google Scholar, CiteFactor, MIAR Index, EuroPub Database, CABELLS, Dergipark (TUBİTAK), Türkiye Citation Index, Sobiad, Asos Index, İdeal Index, and Akademik Index.

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