Merremia emarginata'nın (Burm.f.) biyoaktiviteleri Hallier f. özler ve izole edilmiş bileşikler

Öz

Merremia emarginata (Burm.f.) Hallier f. Convolvulaceae familyasına ait yabani bir bitkidir. Çeşitli geleneksel ilaçlarda şeker hastalığı, epilepsi, romatizma, böbrek ve karaciğer rahatsızlıklarının tedavisinde kullanılır. Kafeik asit, rosmerik asit, skopoletin, tetritol ve vanillic asit gibi bileşikler, bu bitki türünün çeşitli kısımlarından izole edilmiştir. Bu kapsamlı inceleme çalışması, M. emarginata'yı içeren yayınlanmış çalışmalarla ilgili biyoaktiviteleri analiz etmeyi, özetlemeyi ve belgelemeyi amaçlamaktadır. PubMed, ScienceDirect, Scopus, Semantic Scholar ve Web of Science elektronik veritabanları, 1900'den Mayıs 2021'e kadar ilgili yayınlanmış makaleleri elde etmek için kullanıldı. Çeşitli biyoaktiviteler için in vivo ve in vitro bilimsel kanıtlar şu anda mevcuttur. Şimdiye kadar, analjezik, antiartritik, antibakteriyel, antikanser, antidiyabetik, antifungal, antiinflamatuar, antioksidan, antipiretik, diüretik, antiörolitik ve nefroprotektif aktivitelere ilişkin bilimsel kanıtlar mevcuttur ve dört biyoaktif bileşik (sinarin, diasetil, skopoletin ve tetritol) bulunmaktadır. bu bitki türlerinde tespit edilmiştir. Bu çalışma, bu bitki türlerini içeren gelecekteki araştırmalar için temel oluşturmaktadır.

Anahtar Kelimeler

• antioksidan aktivite
• Ayurveda
• Convolvulaceae
• diyabet
• Merremia emarginata
• Siddha Medicine
• Sri Lanka

Bioactivities of Merremia emarginata (Burm.f.) Hallier f. extracts and isolated compounds

Abstract

Merremia emarginata (Burm.f.) Hallier f. is a wild herb that belongs to the Convolvulaceae family. It is used to treat diabetes, epilepsy, rheumatism, kidney and liver disorders in various traditional medicines. Compounds including caffeic acid, rosmeric acid, scopoletin, tetritol, and vanillic acid have been isolated from various parts of this plant species. This comprehensive review work aims to analyze, summarize, and document the bioactivities related to published studies involving M. emarginata. PubMed, ScienceDirect, Scopus, Semantic Scholar, and Web of Science electronic databases were used to obtain the relevant published articles from 1900 to May 2021. There is in vivo and in vitro scientific evidence is currently available for various bioactivities. So far, there is scientific evidence available for analgesic, antiarthritic, antibacterial, anticancer, antidiabetic, antifungal, antiinflammatory, antioxidant, antipyretic, diuretic, antiurolithiatic, and nephroprotective activities and four bioactive compounds (cynarin, diacetyl, scopoletin, and tetritol) have been identified in this plant species. This work provides the basis for future researches involving this plant species.

Keywords

• antioxidant activity
• Ayurveda
• Convolvulaceae
• diabetes
• Merremia emarginata
• Siddha Medicine
• Sri Lanka

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