Karadut (Morus nigra L.) meyvesinde bazı antioksidan aktivitelerinin belirlenmesi

Abstract

Bu çalışma, kara dut (Morus Nigra L.) meyvelerinin bazı bilinen antioksidan özelliklerini incelemek ve değerlendirmek amacıyla yapılmıştır. Moraceae familyasına ait bir bitki olan Morus cinsinin meyveleri, sağlığa yararlı etkileri nedeniyle insan beslenmesinde yaygın olarak tüketilmektedir. Bu bitkilerin meyveleri, flavonoller, antosiyaninler, flavanonoller, fenolik asitler ve alkaloidler gibi çok sayıda biyoaktif bileşen ile K (potasyum), Ca (kalsiyum), Na (sodyum) ve Mg (magnezyum) gibi bazı temel mineraller içerir. Ayrıca, bu meyve vitaminler (örneğin, B1 vitamini ve folik asit), yağ asitleri (linoleik, palmitik ve oleik asitler) ve melatonin açısından da zengin kaynaklardır. Bu bileşik yapının insan sağlığı için çok yönlü fizyolojik ve farmakolojik faydalar sağladığı bildirilmiştir. Son akademik çalışmalar, kara dut meyvesinde yüksek yoğunlukta fenolik karışımlar olduğunu belirlemiş ve bu meyveye olan ilgiyi artırmıştır. Bunun en önemli nedenlerinden biri, siyah dut meyvesinin antosiyaninler ve fenolik bileşikler içermesi ve bunlara ek olarak antimikrobiyal ve antioksidan özelliklere sahip olmasıdır, bu da meyvenin değerinin artmasına neden olmuştur. Kara dut, güçlü bir antioksidan deposudur. Kara dut, çeşitli vitaminler, yüksek protein seviyeleri ve temel mineral elementler içeren zengin bir biyokimyasal bileşime sahiptir. İçerdiği doğal antioksidan bileşikler: enfeksiyon etkenlerine karşı bağışıklık sistemini destekler, hemolitik süreçleri baskılayarak anemiyi önler, kanserojen bileşiklerin biyosentezini inhibe eder, prostaglandin sentezini artırarak antitrombotik etkiler gösterir, aterosklerotik değişiklikleri önler ve hepatotoksik oksidan türlerinin biyokimyasal etkilerini azaltır. Çeşitli çalışmalar, kara dutun belirli kanser türleri üzerinde terapötik ve kemopreventif etkiler gösterebileceğini bildirmiştir. Kara dut örneklerindeki katalaz (CAT) seviyesi ortalama 2,13 U/mg protein, süperoksit dismutaz (SOD) seviyesi ortalama 1,14 U/mg protein ve glutatyon (GSH) seviyesi ortalama 0,16 µmol/mg olarak belirlenmiştir. Bulgular, kara dutun güçlü bir antioksidan aktivite sergilediğini ortaya koymuştur. Buna göre, kara dutun oksidatif stresin neden olduğu hücresel hasara karşı koruyucu bir rol oynayabileceği ve bu nedenle çeşitli kronik hastalıkların önlenmesinde potansiyel bir antioksidan ajan olarak düşünülebileceği sonucuna varılmıştır.

Keywords

• Kara dut meyvesi
• Oksidasyon
• Antioksidan

Determination of some antioxidant activities in the fruit of the black mulberry (Morus nigra L.)

Abstract

This work was conducted to inspect and evaluate some known antioxidant properties of black mulberry (Morus Nigra L.) fruits. Fruits of the Morus Genus, a plant which is a family member of the Moraceae species, are widely consumed as part of the human diet due to their beneficial effects on health. And additionally, these fruits are strong sources of vitamins (e.g., vitamin B1 and folic acid), fatty acids (linoleic, palmitic, and oleic acids), and also melatonin. It has reported that this composite structure provides versatile physiological and pharmacological benefits for human health Recent academic studies have determined high density of phenolic mixtures in black mulberry fruit, forwarding to increased interest in this fruit. One of the most important reasons for this is that the black mulberry fruit contains anthocyanins and phenolic compounds, and in addition to these, it has antimicrobial and antioxidant properties, which have led to its increasing value. Black mulberry offers a rich biochemical composition, containing various vitamins, high levels of protein, and essential mineral elements. The natural antioxidant compounds it contains: support the immune system against infectious agents, prevent anemia by suppressing hemolytic processes, inhibit the biosynthesis of carcinogenic compounds, exhibit antithrombotic effects by increasing prostaglandin synthesis, prevent atherosclerotic changes, and reduce the biochemical effects of hepatotoxic oxidant species. Various studies have reported that black mulberry can exhibit therapeutic and chemopreventive effects on certain types of cancer. The catalase (CAT) level in black mulberry samples was determined to be an average of 2.13 U/mg protein, the superoxide dismutase (SOD) level was an average of 1.14 U/mg protein, and the glutathione (GSH) level was an average of 0.16 µmol/mg. The findings revealed that black mulberry exhibits strong antioxidant activity. Accordingly, it was concluded that black mulberry may play a protective role against oxidative stress-induced cellular damage and, therefore, may be considered a potential antioxidant agent in the prevention of various chronic diseases.

Keywords

• Fruits
• Oxidation
• Antioxidant

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