A Case of Acanthomatous Ameloblastoma in a Anatolian Shepherd (Kangal) Dog

Year 2024, Volume: 4 Issue: 2, 39 - 43, 02.01.2025

Taner Arslan , Mümin Gökhan Şenocak , Esra Modoğlu , Büşra Baykal , Yasemin Akçora , Çağlar Özkalıpçı , Selim Çomaklı

https://doi.org/10.5281/zenodo.14638149

Abstract

Canine acanthomatous ameloblastoma (CAA) is a benign but locally invasive tumor originating from odontogenic epithelium and is one of the most common oral neoplasms in dogs. This report presents a case of CAA in a 6-year-old male Kangal dog, which exhibited progressive growth in the rostral region of the maxilla, accompanied by symptoms such as bleeding gums and loss of appetite. Following physical examination, radiographic evaluations, and histopathological analyses, a diagnosis of CAA was made, and the lesions were excised via radical surgery. Postoperatively, the dog was treated with antibiotics, antiseptic oral spray, anti-inflammatory medications, and H2 receptor antagonists. No signs of malignancy were found in the samples taken from around the oral masses. A follow-up examination on the 70th day after surgery showed no metastasis or recurrence. In conclusion, this case presentation highlights that CAA can occur in the Kangal breed, emphasizes that radical surgery is a good treatment option, and suggests that performing excision involving both soft tissue and bone may prevent recurrence in the mid-term.

Keywords

Maxilla, Odontogenic tumors, Oral, Surgical excision

References

• 1. Murray RL, Aitken ML, Gottfried SD. The Use of Rim Excision as a Treatment for Canine Acanthomatous Ameloblastoma. Jahha. 2010;46(2):91–96. doi: 10.5326/0460091.
• 2. Mayer M, Anthony J. Radiation therapy for oral tumors: canine acanthomatous ameloblastoma. The CVJ. 2007;48(1):99.
• 3. Goldschmidt SL, Bell CM, Hetzel S, Soukup J. Clinical characterization of canine acanthomatous ameloblastoma (CAA) in 263 dogs and the influence of postsurgical histopathological margin on local recurrence. J Vet Dent. 2017;34(4):241–247. doi: 10.1177/0898756417734312.
• 4. Tjepkema J, Bell CM, Soukup JW. Presentation, Diagnostic Imaging, and Clinical Outcome of Conventional Ameloblastoma in Dogs. J Vet Dent. 2020;37(1):6–13. doi: 10.1177/0898756420924847.
• 5. Stancu A, Stan F, Pentena M. Case report of canine achantomatous ameloblastoma. Jfae. 2012;10(3):664–666.
• 6. Peralta S, Marcinczyk MM, Katt WP, Duhamel GE. Confirmation of canine acanthomatous ameloblastoma using RAS Q61R immunohistochemical staining of formalin-fixed paraffin-embedded tissues. Front vet sci. 2023;10. doi:10.3389/fvets.2023.1281022.
• 7. Das S, Nath B, Alim A, Sikder S, Pallab M. Acanthomatous ameloblastoma in a female Spitz dog with rare atypical histomorphology: A case Study. Vet. World 2013;6(4):219–222. doi: 10.5455/vetworld.2013.219-222.
• 8. Mulherin BL. Advanced Imaging of the Oral Cavity. Veterinary Oral Diagnostic Imaging. India;2023:2-50.
• 9. Kafka UCM, Carstens A, Steenkamp G, Symington H. Diagnostic value of magnetic resonance imaging and computed tomography for oral masses in dogs. Jsava 2004;75(4):163–168. doi: 10.4102/jsava.v75i4.476.
• 10. Orhun ÖT. Treatment of Lateral Luxation of the Maxillary Canine Tooth with Extraction and Mucoperiosteal Flap Application in Anatolian Shepherd Dog. Atatürk University J Vet Sci 2022;2(1-2):9-12.
• 11. Şenocak MG. Comparison of spermatic cord ligation and the vas plexus ligation in canine orchiectomy: A prospective clinical study. Vet med sci. 2023;9(5):2015-2021. doi: 10.1002/vms3.1208.