Triglyceride-Glucose Index Could be Used to Predict Severity of Coronary Artery Ectasia

Ersan Oflar; İsmail Ünğan; Cennet Yıldız; Güngör İlayda Bostancı Alp; Büşra Mavi; Fatma Nihan Turhan Çağlar; Demet Erciyes; Alparslan Şahin

Triglyceride-Glucose Index Could be Used to Predict Severity of Coronary Artery Ectasia

Abstract

Introduction: Coronary artery ectasia (CAE) refers to a 1.5 fold increase in coronary artery diameter compared to the normal segment. Although the underlying pathophysiological mechanism is not fully elucidated, coronary atherosclerosis is thought to play a role in more than half of the cases. Triglyceride glucose (TyG) index is an indicator of insulin resistance. In the present study, aimed to evaluated TyG index values in CAE cases and find if a predictive value of TyG index existed. Patients and Methods: Sixty-one patients with CAE (study group) and 64 patients with normal coronary arteries (control group) were included in the study. TyG index was calculated as ln (fasting triglyceride × fasting glucose/2). Results: There were no differences between the two groups with respect to age, sex, diabetes mellitus prevalence, and biochemical parameters including, white blood cell, platelet, lymphocyte, monocyte counts, hemoglobin, hematocrit, urea, glucose, total cholesterol, high density lipoprotein-cholesterol, triglyceride levels and TyG index value. Twenty-five patients (41.0%) had one-vessel involvement, 24 (39.3%) patients had twovessel involvement and 12 (19.7%) patients had three-vessel involvement. Right coronary artery was the most commonly affected vessel (11, 44%), followed by left anterior descending artery (8, 35%), left main coronary artery (4, 16%) and circumflex artery (1, 4%). TyG index was statistically significantly higher in patients who had two/three vessel involvement (8.80 ± 0.48 vs 9.14 ± 0.62, p= 0.027). TyG index had statistically significant correlation with the number of ectatic vessels (r= 0.275, p= 0.032). ROC curve analysis showed that TyG index was useful for the prediction of ectasia severity (AUC= 0.653, 95% CI= 0.515-0.792, p= 0.043). TyG index value of 9.16 had 41.7% sensitivity and 84% specificity for prediction of CAE severity. Conclusion: TyG index, which is easily calculated from biochemical parameters, might be used for the assessment of CAE severity.

Keywords

References

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Details

Primary Language

English

Subjects

Clinical Sciences

Journal Section

Research Article

Authors

Ersan Oflar This is me
0000-0002-0757-2496
Türkiye

İsmail Ünğan This is me
0000-0002-2150-0018
Türkiye

Cennet Yıldız ^* This is me
0000-0003-2456-3206
Türkiye

Güngör İlayda Bostancı Alp This is me
0000-0002-6891-9457
Türkiye

Büşra Mavi This is me
0000-0003-2849-4404
Türkiye

Fatma Nihan Turhan Çağlar This is me
0000-0001-7925-2398
Türkiye

Demet Erciyes This is me
0000-0003-1331-8221
Türkiye

Alparslan Şahin This is me
0000-0002-2496-6905
Türkiye

Publication Date

March 21, 2023

Submission Date

October 27, 2022

Acceptance Date

February 6, 2023

Published in Issue

Year 2023 Volume: 26 Number: 1

IZ

https://izlik.org/JA72ZR66UZ

Cite

RIS / Bibtex

APA

Oflar, E., Ünğan, İ., Yıldız, C., Bostancı Alp, G. İ., Mavi, B., Turhan Çağlar, F. N., Erciyes, D., & Şahin, A. (2023). Triglyceride-Glucose Index Could be Used to Predict Severity of Coronary Artery Ectasia. Koşuyolu Heart Journal, 26(1), 34-39. https://izlik.org/JA72ZR66UZ

AMA

1.Oflar E, Ünğan İ, Yıldız C, et al. Triglyceride-Glucose Index Could be Used to Predict Severity of Coronary Artery Ectasia. Koşuyolu Heart Journal. 2023;26(1):34-39. https://izlik.org/JA72ZR66UZ

Chicago

Oflar, Ersan, İsmail Ünğan, Cennet Yıldız, et al. 2023. “Triglyceride-Glucose Index Could Be Used to Predict Severity of Coronary Artery Ectasia”. Koşuyolu Heart Journal 26 (1): 34-39. https://izlik.org/JA72ZR66UZ.

EndNote

Oflar E, Ünğan İ, Yıldız C, Bostancı Alp Gİ, Mavi B, Turhan Çağlar FN, Erciyes D, Şahin A (March 1, 2023) Triglyceride-Glucose Index Could be Used to Predict Severity of Coronary Artery Ectasia. Koşuyolu Heart Journal 26 1 34–39.

IEEE

[1]E. Oflar et al., “Triglyceride-Glucose Index Could be Used to Predict Severity of Coronary Artery Ectasia”, Koşuyolu Heart Journal, vol. 26, no. 1, pp. 34–39, Mar. 2023, [Online]. Available: https://izlik.org/JA72ZR66UZ

ISNAD

Oflar, Ersan - Ünğan, İsmail - Yıldız, Cennet - Bostancı Alp, Güngör İlayda - Mavi, Büşra - Turhan Çağlar, Fatma Nihan - Erciyes, Demet - Şahin, Alparslan. “Triglyceride-Glucose Index Could Be Used to Predict Severity of Coronary Artery Ectasia”. Koşuyolu Heart Journal 26/1 (March 1, 2023): 34-39. https://izlik.org/JA72ZR66UZ.

JAMA

1.Oflar E, Ünğan İ, Yıldız C, Bostancı Alp Gİ, Mavi B, Turhan Çağlar FN, Erciyes D, Şahin A. Triglyceride-Glucose Index Could be Used to Predict Severity of Coronary Artery Ectasia. Koşuyolu Heart Journal. 2023;26:34–39.

MLA

Oflar, Ersan, et al. “Triglyceride-Glucose Index Could Be Used to Predict Severity of Coronary Artery Ectasia”. Koşuyolu Heart Journal, vol. 26, no. 1, Mar. 2023, pp. 34-39, https://izlik.org/JA72ZR66UZ.

Vancouver

1.Ersan Oflar, İsmail Ünğan, Cennet Yıldız, Güngör İlayda Bostancı Alp, Büşra Mavi, Fatma Nihan Turhan Çağlar, Demet Erciyes, Alparslan Şahin. Triglyceride-Glucose Index Could be Used to Predict Severity of Coronary Artery Ectasia. Koşuyolu Heart Journal [Internet]. 2023 Mar. 1;26(1):34-9. Available from: https://izlik.org/JA72ZR66UZ