Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography

Selahattin Akyol; Hazar Harbalıoğlu; Mustafa Gür; Özcan Erel; Hakim Çelik

Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography

Abstract

Introduction: The oxidized thiol/disulfide couple has been investigated and reported as a potential risk factor for cardiovascular diseases. Additionally, an increased pulse wave velocity has been identified as a predictor of cardiovascular events. Patients and Methods: 262 patients were included in our study. Native and total thiol levels, total disulfide levels, disulfide per total thiol ratios, native thiol per total thiol ratios, and disulfide per native thiol level ratios were calculated. Results: Patients were divided into Pulse Wave Velocity (PWV) low and PWV high groups. Native and total thiol levels were higher in PWV low group compared to PWV high group (p< 0.001 for both). The median disulfide value was higher in PWV high group (p= 0.002). Disulfide per native thiol and disulfide per total thiol ratio values were higher in PWV high group (p< 0.001). Native thiol per total thiol ratios were higher in the PWV-low group (p< 0.001). Conclusion: The disulfide/native thiol pathway may be an indicator for predicting future atherosclerotic cardiovascular events.

Keywords

References

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Details

Primary Language

English

Subjects

Cardiology

Journal Section

Research Article

Authors

Selahattin Akyol ^* This is me
0000-0002-2554-0121
Türkiye

Hazar Harbalıoğlu This is me
0000-0002-6694-814X
Türkiye

Mustafa Gür This is me
0000-0002-2053-8567
Türkiye

Özcan Erel This is me
0000-0002-2996-3236
Türkiye

Hakim Çelik This is me
0000-0002-7565-3394
Türkiye

Publication Date

July 12, 2023

Submission Date

March 22, 2023

Acceptance Date

May 26, 2023

Published in Issue

Year 2023 Volume: 26 Number: 2

IZ

https://izlik.org/JA94NT77NX

Cite

RIS / Bibtex

APA

Akyol, S., Harbalıoğlu, H., Gür, M., Erel, Ö., & Çelik, H. (2023). Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography. Koşuyolu Heart Journal, 26(2), 76-82. https://izlik.org/JA94NT77NX

AMA

1.Akyol S, Harbalıoğlu H, Gür M, Erel Ö, Çelik H. Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography. Koşuyolu Heart Journal. 2023;26(2):76-82. https://izlik.org/JA94NT77NX

Chicago

Akyol, Selahattin, Hazar Harbalıoğlu, Mustafa Gür, Özcan Erel, and Hakim Çelik. 2023. “Impact of Disulfide Thiol Redox Couple on Pulse Wave Velocity in Patients With Normal Coronary Angiography”. Koşuyolu Heart Journal 26 (2): 76-82. https://izlik.org/JA94NT77NX.

EndNote

Akyol S, Harbalıoğlu H, Gür M, Erel Ö, Çelik H (July 1, 2023) Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography. Koşuyolu Heart Journal 26 2 76–82.

IEEE

[1]S. Akyol, H. Harbalıoğlu, M. Gür, Ö. Erel, and H. Çelik, “Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography”, Koşuyolu Heart Journal, vol. 26, no. 2, pp. 76–82, July 2023, [Online]. Available: https://izlik.org/JA94NT77NX

ISNAD

Akyol, Selahattin - Harbalıoğlu, Hazar - Gür, Mustafa - Erel, Özcan - Çelik, Hakim. “Impact of Disulfide Thiol Redox Couple on Pulse Wave Velocity in Patients With Normal Coronary Angiography”. Koşuyolu Heart Journal 26/2 (July 1, 2023): 76-82. https://izlik.org/JA94NT77NX.

JAMA

1.Akyol S, Harbalıoğlu H, Gür M, Erel Ö, Çelik H. Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography. Koşuyolu Heart Journal. 2023;26:76–82.

MLA

Akyol, Selahattin, et al. “Impact of Disulfide Thiol Redox Couple on Pulse Wave Velocity in Patients With Normal Coronary Angiography”. Koşuyolu Heart Journal, vol. 26, no. 2, July 2023, pp. 76-82, https://izlik.org/JA94NT77NX.

Vancouver

1.Selahattin Akyol, Hazar Harbalıoğlu, Mustafa Gür, Özcan Erel, Hakim Çelik. Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography. Koşuyolu Heart Journal [Internet]. 2023 Jul. 1;26(2):76-82. Available from: https://izlik.org/JA94NT77NX