Kontrast Madde Nefropatisi: Antioksidan Tedavi Yönetimi

Abstract

Günümüzde görüntüleme ve girişimsel işlemlerin artış göstermesi ile birlikte kontrast madde kullanımı  giderek artmıştır. Oksidatif stresin kontrast madde nefropatisi patofizyolojisinde önemli rolü vardır. Çeşitli önleyici tedaviler ve yan etkisi daha az düşük osmolar kontrast maddelere rağmen, klinik pratikte tek önleyici tedavi intravenöz iztonik infüzyonudur. Bu yüzden yeni bir koruyucu tedaviye ihtiyaç vardır.

Keywords

• Kontrast,kontrast madde nefropatisi,antioksidan tedavi,anjiyografi

Contrast-Induced Nephropathy: Management by Antioxidant Therapy

Abstract

At present, the number of imaging and interventional procedures using contrast agents is gradually increasing. Oxidative stress plays a significant role in its pathophysiology. Despite the use of various prophylactic therapies and low-osmolar contrast agents with lesser adverse effects, intravenous isotonic fluid infusion is the only method that has been proven to be effective in preventing contrast-induced nephropathy in clinic practice. Therefore, a novel kidney-protecting treatment model is required for contrast-induced nephropathy.

Keywords

• Contrast,contrast-induced nephropathy,antioxidant treatment,angiography

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