A Rarely Seen Type-I Kounis Syndrome Caused By Tetanus Vaccine

Year 2018, Volume: 21 Issue: 1, 82 - 84, 01.04.2018

Harun Kundi , Murat Gök Emrullah Kızıltunç Mustafa Çetin

Abstract

The
pathogenesis mechanism of Kounis syndrome is defined by mast-cell degranulation
that has been amplified to induce acute myocardial infarction in susceptible
individuals. Here, we report a case of Kounis syndrome presented with acute
coronary syndrome after a tetanus vaccine. In addition, all possible other
etiologies, especially ischemia, were excluded.

Keywords

Allergic myocardial infarction, Kounis syndrome, tetanus vaccine

Oldukça Nadir Görülen Tetanoz Aşısının Neden Olduğu Tip 1 Kounis Sendromu

Abstract

Patolojik
mekanizması mast hücrelerinin degranülasyonuna bağlı hassas kişilerde görülen
akut miyokardiyal enfarktüsü Kounis sendromu olarak tanımlanır. Biz burada
tetanoz aşısı sonrası akut koroner sendrom ile başvuran bir Kounis sendromu
bildirdik. Ek olarak, tüm olası sebepler özellikle de iskemi dışlandı.

Keywords

Allerjik kalp krizi, Kounis sendromu, tetanoz aşısı

References

• 1. Kounis NG, Grapsas ND, Goudevenos JA. Unstable angina, allergic angina, and allergic myocardial infarction. Circulation 1999;100:e156-e.
• 2. Kounis NG, Zavras GM. Allergic angina and allergic myocardial infarction. Circulation 1996;94:1789.
• 3. Tavil Y, Turfan M, Türkoğlu S, Abacı A. Kounis syndrome secondary to amoxicillin/clavulanic acid use. Int J Cardiol 2008;124:e4-e7.
• 4. Cervellin G, Neri G, Lippi G, Curti M, Kounis NG. Kounis syndrome triggered by a spider bite. A case report. Int J Cardiol 2016.
• 5. Goto K, Kasama S, Sato M, Kurabayashi M. Myocardial scintigraphic evidence of Kounis syndrome: what is the aetiology of acute coronary syndrome? Eur Heart J 2015:ehv703.
• 6. Nikolaidis LA, Kounis NG, Gradman AH. Allergic angina and allergic myocardial infarction: a new twist on an old syndrome. The Canadian Journal of Cardiology 2002;18:508-11.
• 7. Kounis NG. Kounis syndrome (allergic angina and allergic myocardial infarction): a natural paradigm? Int J Cardiol 2006;110:7-14.
• 8. Genovese A, Spadaro G. Highlights in cardiovascular effects of histamine and HI-receptor ansgonists. Allergy 1997;52:67-78.
• 9. Kounis NG, Mazarakis A, Tsigkas G, Giannopoulos S, Goudevenos J. Kounis syndrome: a new twist on an old disease. Future Cardiology 2011;7:805-24.