Research Article
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Experience at a Tertiary Center and Short-term Results in Carotid Artery Stent Implantation

Year 2018, Volume: 21 Issue: 2, 93 - 97, 19.08.2018

Abstract

Introduction: Patients
with carotid artery stenosis are at increased risk for stroke and
cardiovascular death. Here, we aimed to present the short-term results of
carotid artery endovascular procedures performed at our tertiary center.



Patients and Methods:
Totally,
220 patients [169 males, 51 females; median age, 66 (45-83) years] who
underwent carotid artery stent (CAS) placement were included in the study.
Post-procedural myocardial infarction (MI); major adverse events, including
stroke and death; and procedural hypotension and transient cerebral ischemic
events were evaluated in the 1-month period.



Results: Totally,
231 carotid stenoses and stents were implanted in all patients. Eleven patients
(5%) were treated using staged CAS owing to bilateral carotid artery disease.
The technical success rate was 97%. One (0.4%) patient died; however, no MI was
observed during successful CAS implantation. Two patients (0.9%) developed
ischemic cerebrovascular events 24 hours after the procedure. Totally, 5
patients (2.2%) had a transient ischemic attack in the 1-month period after the
procedure. Eight patients (3.6%) developed procedural hypotension. No patient
had hyperperfusion syndrome.



Conclusion: CAS placement can be safely
performed with low major adverse cerebrovascular events and high success rates
in symptomatic or asymptomatic patients.

References

  • 1. Aydıner O, Boztosun B, Sirvanci M, Akçakoyun M, Karaman K, Aksoy T, et al. Early and late outcomes of carotid artery stenting. Anadolu Kardiyol Derg 2007;7:152-7.
  • 2. Moresoli P, Habib B, Reynier P, Secrest MH, Eisenberg MJ, Filion KB. Carotid stenting versus endarterectomy for asymptomatic carotid artery stenosis: a systematic review and meta-analysis. Stroke 2017;48:2150-7.
  • 3. Meschia JF, Brott TG, Hobson RW. Diagnosis and invasive management of carotid atherosclerotic stenosis. Mayo Clin Proc 2007;82:851-8.
  • 4. Brott TG, Hobson RW II, Howard G, Roubin GS, Clark WM, Brooks W, et al; CREST Investigators. Stenting versus endarterectomy for treatment of carotid-artery stenosis (CREST). N Engl J Med 2010;363:11-23. Erratum in: N Engl J Med 2010;363:498. N Engl J Med 2010;363:198.
  • 5. Li Y, Yang JJ, Zhu SH, Xu B, Wang L. Long-term efficacy and safety of carotid artery stenting versus endarterectomy: A meta-analysis of randomized controlled trials. PLoS One 2017;12:e0180804.
  • 6. Arhuidese IJ, Rizwan M, Nejim B, Malas M. Outcomes of primary and secondary carotid artery stenting. Stroke 2017;48:3086-92.
  • 7. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD; Joint ESC/ACCF/AHA/WHF Task Force for Universal Definition of Myocardial Infarction; Authors/Task Force Members Chairpersons, Thygesen K, Alpert JS, White HD; Biomarker Subcommittee, Jaffe AS, Katus HA, Apple FS, Lindahl B, Morrow DA; ECG Subcommittee, Chaitman BR, Clemmensen PM, Johanson P, Hod H; Imaging Subcommittee, Underwood R, Bax JJ, Bonow JJ, Pinto F, Gibbons RJ; Classification Subcommittee, Fox KA, Atar D, Newby LK, Galvani M, Hamm CW; Intervention Subcommittee, Uretsky BF, Steg PG, Wijns W, Bassand JP, Menasche P, Ravkilde J; Trials & Registries Subcommittee, Ohman EM, Antman EM, Wallentin LC, Armstrong PW, Simoons ML; Trials & Registries Subcommittee, Januzzi JL, Nieminen MS, Gheorghiade M, Filippatos G; Trials & Registries Subcommittee, Luepker RV, Fortmann SP, Rosamond WD, Levy D, Wood D; Trials & Registries Subcommittee, Smith SC, Hu D, Lopez-Sendon JL, Robertson RM, Weaver D, Tendera M, Bove AA, Parkhomenko AN, Vasilieva EJ, Mendis S; ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S; Document Reviewers, Morais J, Aguiar C, Almahmeed W, Arnar DO, Barili F, Bloch KD, Bolger AF, Botker HE, Bozkurt B, Bugiardini R, Cannon C, de Lemos J, Eberli FR, Escobar E, Hlatky M, James S, Kern KB, Moliterno DJ, Mueller C, Neskovic AN, Pieske BM, Schulman SP, Storey RF, Taubert KA, Vranckx P, Wagner DR. Third universal definition of myocardial infarction. J Am Coll Cardiol 2012;60:1581-98.
  • 8. U-King-Im JM, Trivedi RA, Cross JJ, Higgins NJ, Hollingworth W, Graves M, et al. Measuring carotid stenosis on contrast enhanced magnetic resonance angiography: diagnostic performance and reproducibility of 3 different methods. Stroke 2004;35:2083-8.
  • 9. Meschia JF, Klaas JP, Brown RD Jr, Brott TG. Evaluation and Management of Atherosclerotic Carotid Stenosis. Mayo Clin Proc 2017;92:1144-57.
  • 10. Phatouros CC, Higashida RT, Malek AM, Meyers PM, Lempert TE, Dowd CF, et al. Carotid artery stent placement for atherosclerotic disease: rationale, technique, and current status. Radiology 2000;217:26-41.
  • 11. Sheffet AJ, Roubin G, Howard G, Howard V, Moore W, Meschia JF, et al. Design of the carotid revascularization endarterectomy vs. stenting trial (CREST). Int J Stroke 2010;5:40-6.
  • 12. Gurm HS, Yadav JS, Fayad P, Katzen BT, Mishkel GJ, Bajwa TK, et al; SAPPHIRE Investigators. Longterm results of carotid stenting versus endarterectomy in high-risk patients. N Engl J Med 2008;358:1572-9.
  • 13. Mas JL, Trinquart L, Leys D, Albucher JF, Rousseau H, Viguier A, et al; EVA-3S Investigators. Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial: results up to 4 years from a randomised, multicentre trial. Lancet Neurol 2008;7:885-92.
  • 14. Akar Bayram N, Bozkurt E, Ayhan H, Gürkaş E, Orhan G, Ak F, et al. Early outcomes of carotid artery stenting. Perfusion 2012;27:146-9.
  • 15. Arslan S, Köklü E, Yüksel IÖ, Çağırcı G, Bayar N, Yılmaz A, et al. Two-year results of carotid artery stenting. Turk Kardiyol Dern Ars 2014;42:429-34.
  • 16. Sahin M, Açar G, Ozkan B, Alıcı G, Yazıcıoglu MV, Bulut M, et al. Comparison of short-term outcomes after carotid artery stenting according to different stent designs. Postepy Kardiol Interwencyjnej 2013;9:121-5.
  • 17. ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery Developed in Collaboration With the American Academy of Neurology and Society of Cardiovascular Computed Tomography. J Am Coll Cardiol 2011;57:e16-e94.
  • 18. Nii K, Tsutsumi M, Aikawa H, Hamaguchi S, Etou H, Sakamoto K, et al. Incidence of hemodynamicdepression after carotid artery stenting using different self-expandable stent types. Neurol Med Chir 2011;51:556-60.

Karotis Artere Stent Yerleştirme İşleminde Tersiyer Merkez Deneyimi ve Kısa Dönem Sonuçlar

Year 2018, Volume: 21 Issue: 2, 93 - 97, 19.08.2018

Abstract

Giriş: Karotis arter darlığı olan hastalar inme ve
kardiyovasküler ölüm açısından artmış risk altındadır. Bizim bu çalışmadaki amacımız,
karotis artere endovasküler girişiminde tersiyer merkez olarak kısa dönem sonuçlarını
sunmaktır.



Hastalar ve Yöntem: Karotis artere stent yerleştirme
(KAS) işlemi uygulanan 220 [169 erkek ve 51 kadın, ortanca yaş 66 (45-83)]
hasta çalışmaya dahil edildi. Tüm olgularda distal koruma cihazı kullanıldı.
İşlem sonrası bir aylık dönemdeki miyokart infarktüsü (Mİ), inme ve ölümü
içeren majör advers olaylar ve işleme bağlı hipotansiyon ve geçici serebral
iskemik olaylar değerlendirildi.



Bulgular: İki yüz otuz bir karotis arter darlığına stent
implantasyonu kararı verildi. On bir hasta (%5) bilateral karotis arter darlığı
nedeniyle aşamalı KAS işlemi uygulandı. İşlem başarısı %97 bulundu. Başarılı
şekilde KAS işlemi uyguladığımız 1 (%0.4) hastada ölüm gelişti ama hiçbirinde
Mİ görülmedi. İki hastada (%0.9) işlemden 24 saat sonra sekelli iskemik
serebrovasküler olay gelişti. Toplam 5 (%2.2) hastada işlem sonrası bir aylık
dönemde geçici iskemik atak gözlendi. Sekiz (%3.6) hastada işleme bağlı
hipotansiyon gelişti. Hiçbir hastada hiperperfüzyon sendromu yaşanmadı.



Sonuç: KAS işleminin semptomlu
veya semptomsuz hastalarda düşük majör advers serebrovasküler olaylar ve yüksek
başarı oranları ile güvenli bir şekilde yapılabileceğini düşünmekteyiz.

References

  • 1. Aydıner O, Boztosun B, Sirvanci M, Akçakoyun M, Karaman K, Aksoy T, et al. Early and late outcomes of carotid artery stenting. Anadolu Kardiyol Derg 2007;7:152-7.
  • 2. Moresoli P, Habib B, Reynier P, Secrest MH, Eisenberg MJ, Filion KB. Carotid stenting versus endarterectomy for asymptomatic carotid artery stenosis: a systematic review and meta-analysis. Stroke 2017;48:2150-7.
  • 3. Meschia JF, Brott TG, Hobson RW. Diagnosis and invasive management of carotid atherosclerotic stenosis. Mayo Clin Proc 2007;82:851-8.
  • 4. Brott TG, Hobson RW II, Howard G, Roubin GS, Clark WM, Brooks W, et al; CREST Investigators. Stenting versus endarterectomy for treatment of carotid-artery stenosis (CREST). N Engl J Med 2010;363:11-23. Erratum in: N Engl J Med 2010;363:498. N Engl J Med 2010;363:198.
  • 5. Li Y, Yang JJ, Zhu SH, Xu B, Wang L. Long-term efficacy and safety of carotid artery stenting versus endarterectomy: A meta-analysis of randomized controlled trials. PLoS One 2017;12:e0180804.
  • 6. Arhuidese IJ, Rizwan M, Nejim B, Malas M. Outcomes of primary and secondary carotid artery stenting. Stroke 2017;48:3086-92.
  • 7. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD; Joint ESC/ACCF/AHA/WHF Task Force for Universal Definition of Myocardial Infarction; Authors/Task Force Members Chairpersons, Thygesen K, Alpert JS, White HD; Biomarker Subcommittee, Jaffe AS, Katus HA, Apple FS, Lindahl B, Morrow DA; ECG Subcommittee, Chaitman BR, Clemmensen PM, Johanson P, Hod H; Imaging Subcommittee, Underwood R, Bax JJ, Bonow JJ, Pinto F, Gibbons RJ; Classification Subcommittee, Fox KA, Atar D, Newby LK, Galvani M, Hamm CW; Intervention Subcommittee, Uretsky BF, Steg PG, Wijns W, Bassand JP, Menasche P, Ravkilde J; Trials & Registries Subcommittee, Ohman EM, Antman EM, Wallentin LC, Armstrong PW, Simoons ML; Trials & Registries Subcommittee, Januzzi JL, Nieminen MS, Gheorghiade M, Filippatos G; Trials & Registries Subcommittee, Luepker RV, Fortmann SP, Rosamond WD, Levy D, Wood D; Trials & Registries Subcommittee, Smith SC, Hu D, Lopez-Sendon JL, Robertson RM, Weaver D, Tendera M, Bove AA, Parkhomenko AN, Vasilieva EJ, Mendis S; ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S; Document Reviewers, Morais J, Aguiar C, Almahmeed W, Arnar DO, Barili F, Bloch KD, Bolger AF, Botker HE, Bozkurt B, Bugiardini R, Cannon C, de Lemos J, Eberli FR, Escobar E, Hlatky M, James S, Kern KB, Moliterno DJ, Mueller C, Neskovic AN, Pieske BM, Schulman SP, Storey RF, Taubert KA, Vranckx P, Wagner DR. Third universal definition of myocardial infarction. J Am Coll Cardiol 2012;60:1581-98.
  • 8. U-King-Im JM, Trivedi RA, Cross JJ, Higgins NJ, Hollingworth W, Graves M, et al. Measuring carotid stenosis on contrast enhanced magnetic resonance angiography: diagnostic performance and reproducibility of 3 different methods. Stroke 2004;35:2083-8.
  • 9. Meschia JF, Klaas JP, Brown RD Jr, Brott TG. Evaluation and Management of Atherosclerotic Carotid Stenosis. Mayo Clin Proc 2017;92:1144-57.
  • 10. Phatouros CC, Higashida RT, Malek AM, Meyers PM, Lempert TE, Dowd CF, et al. Carotid artery stent placement for atherosclerotic disease: rationale, technique, and current status. Radiology 2000;217:26-41.
  • 11. Sheffet AJ, Roubin G, Howard G, Howard V, Moore W, Meschia JF, et al. Design of the carotid revascularization endarterectomy vs. stenting trial (CREST). Int J Stroke 2010;5:40-6.
  • 12. Gurm HS, Yadav JS, Fayad P, Katzen BT, Mishkel GJ, Bajwa TK, et al; SAPPHIRE Investigators. Longterm results of carotid stenting versus endarterectomy in high-risk patients. N Engl J Med 2008;358:1572-9.
  • 13. Mas JL, Trinquart L, Leys D, Albucher JF, Rousseau H, Viguier A, et al; EVA-3S Investigators. Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial: results up to 4 years from a randomised, multicentre trial. Lancet Neurol 2008;7:885-92.
  • 14. Akar Bayram N, Bozkurt E, Ayhan H, Gürkaş E, Orhan G, Ak F, et al. Early outcomes of carotid artery stenting. Perfusion 2012;27:146-9.
  • 15. Arslan S, Köklü E, Yüksel IÖ, Çağırcı G, Bayar N, Yılmaz A, et al. Two-year results of carotid artery stenting. Turk Kardiyol Dern Ars 2014;42:429-34.
  • 16. Sahin M, Açar G, Ozkan B, Alıcı G, Yazıcıoglu MV, Bulut M, et al. Comparison of short-term outcomes after carotid artery stenting according to different stent designs. Postepy Kardiol Interwencyjnej 2013;9:121-5.
  • 17. ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery Developed in Collaboration With the American Academy of Neurology and Society of Cardiovascular Computed Tomography. J Am Coll Cardiol 2011;57:e16-e94.
  • 18. Nii K, Tsutsumi M, Aikawa H, Hamaguchi S, Etou H, Sakamoto K, et al. Incidence of hemodynamicdepression after carotid artery stenting using different self-expandable stent types. Neurol Med Chir 2011;51:556-60.
There are 18 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Original Investigations
Authors

Sinan Cerşit

Müslüm Şahin This is me

Publication Date August 19, 2018
Published in Issue Year 2018 Volume: 21 Issue: 2

Cite

Vancouver Cerşit S, Şahin M. Karotis Artere Stent Yerleştirme İşleminde Tersiyer Merkez Deneyimi ve Kısa Dönem Sonuçlar. Koşuyolu Heart Journal. 2018;21(2):93-7.