Psoriazis Vulgarisli Hastalarda Preklinik Sol Ventrikül Fonksiyon Bozukluğunun İki Boyutlu Speckle Tracking Ekokardiyografi ile Tespiti

Year 2017, Volume: 20 Issue: 1, 40 - 46, 03.04.2017

Sinan İnci Özgül Muştu Koryürek Gökay Nar Gökhan Aksan İbrahim İzgü

Abstract

Giriş: Bu çalışmada bilinen kalp hastalığı olmayan psoriazis vulgaris (PV)’li
hastalarda subklinik sol ventrikül işlev bozukluğunun araştırılması
hedeflenmiştir.

Hastalar ve
Yöntem: Çalışmaya koroner arter hastalığı ve kalp yetersizliği olmayan
45 psoriazis vulgarisli hasta (22 E, 23 K, yaş 39 ± 14 yıl) ve yaş, cinsiyeti
uygun 45 sağlıklı kontrol grubu alındı. Sol ventrikül işlevleri speckle
tracking ekokardiyografi (STE) ile longitudinal olarak apikal 4-3-2 boşluk
görüntülerle mevcut software kullanılarak analiz edildi (QLAB 6.0).

Bulgular: İki grup arasında standart ekokardiyografi ve Doppler parametreleri
arasında fark yoktu. Psoriazis vulgaris hastalarında bazal septum ve lateral
mitral anulustan doku Doppler görüntülemede S’ ve E’ parametrelerinde anlamlı
azalma görüldü. Sol ventrikül longitudinal ölçümlerde longitudinal strain ve
strain  hız parametreleri kontrol grubu
ile karşılaştırıldığında anlamlı olarak azalmıştı. Global longitudinal strain
(GLS) PV hasta grubunda %-20.8 ± 4.11 ve kontrol grubunda %-22.9 ± 3.73 olarak
ölçüldü (p= 0.035). PV hasta grubunda GLS ile hastalık süresi ve şiddeti
arasında anlamlı negatif korelasyon vardı.

Sonuç: Çalışmamız PV’li hastaların standart
ekokardiyografi parametreleri normal olmasına rağmen STE ile sol ventrikül
fonksiyonlarının azaldığını göstermiştir.

Keywords

Sol ventrikül fonksiyonları, psoriazis vulgaris, speckle tracking ekokardiyografi

Determining Preclinical Left Ventricular Function Impairment with Two-Dimensional Speckle Tracking Echocardiography in Patients with Psoriasis Vulgaris

Abstract

Introduction:
The
purpose of study was to examine subclinical left ventricular function
impairment in patients with psoriasis vulgaris (PV) without any known heart
diseases.

Patients
and Methods: In total, 45 patients (22 males and 23 females; age: 39 ±
14 years) with psoriasis vulgaris who did not have any known coronary artery
disease and cardiac insufficiency and a control group consisting of 45 healthy
participants whose ages and genders matched those of participants in the study
group were included in our study. Left ventricular functions were
longitudinally analysed with speckle tracking echocardiography (STE) and with
apical 4-3-2 chamber images using the current software (QLAB 6.0).

Results: There
were no differences between the two groups in terms of standard
echocardiography and Doppler parameters. A significant decrease was observed in
S’ and E’ parameters of patients with psoriasis vulgaris on tissue Doppler
imaging from the basal septum and lateral mitral annulus. Compared with the
control group, the longitudinal strain and strain speed parameters were found
to decrease at a significant level in left ventricular longitudinal
measurements. The global longitudinal strain (GLS) was measured as -20.8 ±
4.11% in the study group and as -22.9 ± 3.73% in the control group (p= 0.035).
There was a significant negative correlation between GLS and the duration and
severity of disease in the study group.

Conclusion: We showed that although the standard
echocardiography parameters were normal, STE and left ventricular functions of
patients with PV decreased.

Keywords

Left ventricular functions, psoriasis vulgaris, speckle tracking echocardiography

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