Kontrast Madde Nefropatisi: Antioksidan Tedavi Yönetimi

Year 2017, Volume: 20 Issue: 1, 59 - 62, 03.04.2017

Mutlu Büyüklü , Eftal Murat Bakırcı Hüsnü Değirmenci Gökhan Ceyhun Ergün Topal

Abstract

Günümüzde
görüntüleme ve girişimsel işlemlerin artış göstermesi ile birlikte kontrast
madde kullanımı  giderek artmıştır.
Oksidatif stresin kontrast madde nefropatisi patofizyolojisinde önemli rolü
vardır. Çeşitli önleyici tedaviler ve yan etkisi daha az düşük osmolar kontrast
maddelere rağmen, klinik pratikte tek önleyici tedavi intravenöz iztonik
infüzyonudur. Bu yüzden yeni bir koruyucu tedaviye ihtiyaç vardır.

Keywords

Kontrast, kontrast madde nefropatisi, antioksidan tedavi, anjiyografi

Contrast-Induced Nephropathy: Management by Antioxidant Therapy

Abstract

At
present, the number of imaging and interventional procedures using contrast
agents is gradually increasing. Oxidative stress plays a significant role in
its pathophysiology. Despite the use of various prophylactic therapies and
low-osmolar contrast agents with lesser adverse effects, intravenous isotonic
fluid infusion is the only method that has been proven to be effective in
preventing contrast-induced nephropathy in clinic practice. Therefore, a novel
kidney-protecting treatment model is required for contrast-induced nephropathy.

Keywords

Contrast, contrast-induced nephropathy, antioxidant treatment, angiography

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