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Tıkayıcı Mekanik Aort Kapak Trombozu Olan Bir Hastanın Seri Floroskopi Kılavuzluğunda Pıhtı Eritici İlaç ile Tedavisi

Year 2016, Volume: 19 Issue: 3, 191 - 194, 01.12.2016

Abstract











Protez kapak
trombozu genellikle yetersiz antikoagüle edilmiş hastalarda rastlanan hayatı
tehdit edici bir komplikasyondur. Protez kapak trombozu tanısında 2-boyutlu ve
gerçek zamanlı 3-boyutlu transözafajeal ekokardiyografi altın standart
görüntüleme yöntemleri olmasına rağmen, bu yöntemlerle aort konumundaki protez
kapaklar çok net değerlendirilemeyebilir. Bu durum protez aort kapak trombozu
nedeniyle trombolitik  tedavi alan
hastaların takibinde önemli bir problem oluşturur. Floroskopi bu şekilde kapak
hareketlerinde kısıtlılık olan hastaların takibinde kapak hareketleri hakkında
değerli bilgiler sunan alternatif noninvaziv görüntüleme yöntemidir. Burada bir
protez aort kapak trombozu tanılı olguda seri floroskopi kılavuzluğunda düşük
doz (25 mg) doku plazminojen aktivatörünün çok yavaş infüzyonu (25 saat) ile
yapılan trombolitik tedaviyi sunmaktayız.



References

  • 1. Özkan M, Çakal B, Karakoyun S, Gürsoy OM, Çevik C, Kalçık M, et al. Thrombolytic therapy for the treatment of prosthetic heart valve thrombosis in pregnancy with low-dose, slow infusion of tissue-type plasminogen activator. Circulation 2013;128:532-40.
  • 2. Özkan M, Gündüz S, Biteker M, Astarcioglu MA, Çevik C, Kaynak E, et al. Comparison of different TEE-guided thrombolytic regimens for prosthetic valve thrombosis: the TROIA trial. JACC Cardiovasc Imaging 2013;6:206-16.
  • 3. Montorsi P, De Bernardi F, Muratori M, Cavoretto D, Pepi M. Role of cine-fluoroscopy, transthoracic, and transesophageal echocardiography in patients with suspected prosthetic heart valve thrombosis. Am J Cardiol 2000;85:58-64.
  • 4. Licata A, Matthai WH Jr. Evaluating the etiology of mechanical valve obstruction: use of clinical parameters, fluoroscopy, and echocardiography. Catheter Cardiovasc Interv 2002;55:495-500.
  • 5. Muratori M, Montorsi P, Maffessanti F, Teruzzi G, Zoghbi WA, Gripari P, et al. Dysfunction of bileaflet aortic prosthesis: accuracy of echocardiography versus fluoroscopy. JACC Cardiovasc Imaging 2013;6:196-205.
  • 6. Montorsi P, Cavoretto D, Alimento M, Muratori M, Pepi M. Prosthetic mitral valve thrombosis: can fluoroscopy predict the efficacy of thrombolytic treatment? Circulation 2003;108(Suppl 1):II79-84.
  • 7. Montorsi P, Cavoretto D, Ballerini G. Thrombosis of mechanical heart valve prostheses: revisiting the role of fluoroscopy. Br J Radiol 2000;73:76-9.
  • 8. Cianciulli TF, Lax JA, Saccheri MC, Guidoin R, Salvado CM, Fernández AJ, et al. Retrieval of a leaflet escaped in a Tri-technologies bileaflet mechanical prosthetic valve. Eur J Echocardiogr 2008;9:65-8.

Serial Fluoroscopy Guided Fibrinolytic Therapy in a Patient with Obstructive Mechanical Aortic Valve Thrombosis

Year 2016, Volume: 19 Issue: 3, 191 - 194, 01.12.2016

Abstract











Prosthetic
valve thrombosis is a life-threatening complication, which is most commonly
seen in patients with poor anticoagulation. Although two-dimensional and
real-time three-dimensional transesophageal echocardiography are the gold
standard imaging modalities for the diagnosis of prosthetic valve thrombosis,
prosthetic valves in aortic position may not be evaluated precisely. This is a
serious problem during the follow-up of the patients who receive thrombolytic
therapy for aortic valve thrombosis. Fluoroscopy is an alternative noninvasive
imaging method, which provides valuable information about leaflet motion and
may be used for such cases with restricted leaflets. Here, we report a case of
aortic valve thrombosis that was managed with low-dose (25 mg) and ultra-slow
(25 hours) infusion of tissue-type plasminogen activator under the guidance of
serial fluoroscopy.



References

  • 1. Özkan M, Çakal B, Karakoyun S, Gürsoy OM, Çevik C, Kalçık M, et al. Thrombolytic therapy for the treatment of prosthetic heart valve thrombosis in pregnancy with low-dose, slow infusion of tissue-type plasminogen activator. Circulation 2013;128:532-40.
  • 2. Özkan M, Gündüz S, Biteker M, Astarcioglu MA, Çevik C, Kaynak E, et al. Comparison of different TEE-guided thrombolytic regimens for prosthetic valve thrombosis: the TROIA trial. JACC Cardiovasc Imaging 2013;6:206-16.
  • 3. Montorsi P, De Bernardi F, Muratori M, Cavoretto D, Pepi M. Role of cine-fluoroscopy, transthoracic, and transesophageal echocardiography in patients with suspected prosthetic heart valve thrombosis. Am J Cardiol 2000;85:58-64.
  • 4. Licata A, Matthai WH Jr. Evaluating the etiology of mechanical valve obstruction: use of clinical parameters, fluoroscopy, and echocardiography. Catheter Cardiovasc Interv 2002;55:495-500.
  • 5. Muratori M, Montorsi P, Maffessanti F, Teruzzi G, Zoghbi WA, Gripari P, et al. Dysfunction of bileaflet aortic prosthesis: accuracy of echocardiography versus fluoroscopy. JACC Cardiovasc Imaging 2013;6:196-205.
  • 6. Montorsi P, Cavoretto D, Alimento M, Muratori M, Pepi M. Prosthetic mitral valve thrombosis: can fluoroscopy predict the efficacy of thrombolytic treatment? Circulation 2003;108(Suppl 1):II79-84.
  • 7. Montorsi P, Cavoretto D, Ballerini G. Thrombosis of mechanical heart valve prostheses: revisiting the role of fluoroscopy. Br J Radiol 2000;73:76-9.
  • 8. Cianciulli TF, Lax JA, Saccheri MC, Guidoin R, Salvado CM, Fernández AJ, et al. Retrieval of a leaflet escaped in a Tri-technologies bileaflet mechanical prosthetic valve. Eur J Echocardiogr 2008;9:65-8.
There are 8 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case Report
Authors

Macit Kalçık

Mahmut Yesin This is me

Mustafa Ozan Gürsoy This is me

Mustafa Yıldız This is me

Mehmet Özkan This is me

Publication Date December 1, 2016
Published in Issue Year 2016 Volume: 19 Issue: 3

Cite

Vancouver Kalçık M, Yesin M, Gürsoy MO, Yıldız M, Özkan M. Serial Fluoroscopy Guided Fibrinolytic Therapy in a Patient with Obstructive Mechanical Aortic Valve Thrombosis. Koşuyolu Heart Journal. 2016;19(3):191-4.