Abstract
Elli bir yaşında mitral yetmezlik
tanısı ile cerrahi tedavi için yatırılan bir hastayı sunduk. Dört yıl önce
primer antifosfolipid tanısı almış ve trombositopeni hikayesi mevcut.
Postoperatif titiz antikoagülan tedavi ile mitral kapak başarılı bir şekilde
replase edildi ve postoperatif dönem olaysız geçti. Antifosfolipid sendromlu
hastalarda kardiyak cerrahide yüksek mortalite ve morbidite oranları
bildirilmiştir. Postoperatif dönemde hemen antikoagülan tedavinin başlanması
trombozun önlenmesi açısından çok önemlidir.
References
- 1. Vila P, Hernandez M, Lopez-Fernandez M. Prevalance, follow-up and clinical significance of the anticardiolipin antibodies in normal subjects. Thromb Haemost 1994;72:209-13.
- 2. Turiel M, Muzzupappa S, Gottardi B. Evaluation of cardiac abnormalities and embolic sources in primary antiphospholipid syndrome by transesophageal achocardiography. Lupus 2000;9:406-12.
- 3. Kaplan SD, Chartash EK, Pizzarello RA. Cardiac manifestationsof the antiphospholipid syndrome. Am Heart J 1992;124:1331-8.
- 4. Matsuyama K, Ueda Y, Ogino H. Aortic valve replacement for aortic regurgitation in a patient with primary antiphospholipid syndrome. Am Heart J 1999;63:973-8.
- 5. Kato Y, Isobe F, Sasaki Y. Mitral insufficiency associated with primary antiphospholipid syndrome and chronic renal failure. Jpn J Thorac Cardiovasc Surg 2001;49:171-4.
- 6. Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006;4:295-306.
- 7. Araki Y, Tajima K, Shimomura T. A case report on mitral valve replacement associated with antiphospholipid syndrome in systemic lupus erythematosus. Kyobu Geka 1997;50:480-2.
- 8. Massoudy P, Cetin SM, Thielmann M, Kienbaum P, Piotrowski JA, Marggraf G, et al. Antiphospholipid syndrome in cardiac surgery-an underestimated coagulation disorder? Eur J Cardiothorac Surg 2005;28:133-7.
- 9. Bardakçı H. Antifosfolipid sendrom ve Kalp Cerrahisi. TJIC 2007;11:77-82.
- 10. Engelberger L, Streich M, Tevaearai H, Carrel TP. Different anticoagulation strategies in off-pump coronary artery bypass operations: a European survey. Interact Cardiovasc Thorac Surg 2008;7:378-82.
- 11. Ruiz-Irastora G, Khamashta MA, Hunt BJ, Escudero A, Cuadrado MJ, Hughes GR. Bleeding and recurrent thrombosis in definite antiphospholipid syndrome. Analysis of a series of 66 patients treated with oral anticoagulation to a target international normalized ratio of 3.5. Arch Intern Med 2002;162:1164-9.
Abstract
We report a 51-year-old patient who
was diagnosed with mitral insufficiency and was admitted to our hospital for
surgical treatment. The patient was diagnosed with primary antiphospholipid
syndrome (PAPS) before 4 years and had a history of thrombocytopenia. Mitral
valve replacement was successfully performed with postoperative strict
anticoagulant therapy, and the postoperative course was uneventful. Cardiac
surgery in APS patients has been associated with high morbidity and mortality.
Therefore, it is very important to initiate anticoagulant therapy immediately
after the operation to prevent thrombosis.
References
- 1. Vila P, Hernandez M, Lopez-Fernandez M. Prevalance, follow-up and clinical significance of the anticardiolipin antibodies in normal subjects. Thromb Haemost 1994;72:209-13.
- 2. Turiel M, Muzzupappa S, Gottardi B. Evaluation of cardiac abnormalities and embolic sources in primary antiphospholipid syndrome by transesophageal achocardiography. Lupus 2000;9:406-12.
- 3. Kaplan SD, Chartash EK, Pizzarello RA. Cardiac manifestationsof the antiphospholipid syndrome. Am Heart J 1992;124:1331-8.
- 4. Matsuyama K, Ueda Y, Ogino H. Aortic valve replacement for aortic regurgitation in a patient with primary antiphospholipid syndrome. Am Heart J 1999;63:973-8.
- 5. Kato Y, Isobe F, Sasaki Y. Mitral insufficiency associated with primary antiphospholipid syndrome and chronic renal failure. Jpn J Thorac Cardiovasc Surg 2001;49:171-4.
- 6. Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006;4:295-306.
- 7. Araki Y, Tajima K, Shimomura T. A case report on mitral valve replacement associated with antiphospholipid syndrome in systemic lupus erythematosus. Kyobu Geka 1997;50:480-2.
- 8. Massoudy P, Cetin SM, Thielmann M, Kienbaum P, Piotrowski JA, Marggraf G, et al. Antiphospholipid syndrome in cardiac surgery-an underestimated coagulation disorder? Eur J Cardiothorac Surg 2005;28:133-7.
- 9. Bardakçı H. Antifosfolipid sendrom ve Kalp Cerrahisi. TJIC 2007;11:77-82.
- 10. Engelberger L, Streich M, Tevaearai H, Carrel TP. Different anticoagulation strategies in off-pump coronary artery bypass operations: a European survey. Interact Cardiovasc Thorac Surg 2008;7:378-82.
- 11. Ruiz-Irastora G, Khamashta MA, Hunt BJ, Escudero A, Cuadrado MJ, Hughes GR. Bleeding and recurrent thrombosis in definite antiphospholipid syndrome. Analysis of a series of 66 patients treated with oral anticoagulation to a target international normalized ratio of 3.5. Arch Intern Med 2002;162:1164-9.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Case Report |
| Authors | |
| Publication Date | April 4, 2016 |
| Published in Issue | Year 2016 Volume: 19 Issue: 1 |
