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Year 2021, Volume: 24 Issue: 1, 1 - 7, 01.04.2021

Abstract

References

  • 1. Collet JP, Thiele H. The ‘Ten Commandments’ for the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2020;41:3495-7.
  • 2. Aktoz M, Altay H, Aslanger E, Atalar E, Atar I, Aytekin V, et al. Consensus Report from Turkish Society of Cardiology: COVID-19 and Cardiovascular Diseases. What cardiologists should know. (25th March 2020). Turk Kardiyol Dern Ars 2020;48:1-48.
  • 3. Romaguera R, Cruz-Gonzales I, Ojeda S, Jimenez-Candil J, Calvo D, Seara JG, et al. Consensus document of the Interventional Cardiology and Heart Rhythm Associations of the Spanish Society of Cardiology on the management of invasive cardiac procedure rooms during the COVID-19 coronavirus outbreak. REC Interv Cardiol 2020;2:106-11.
  • 4. Arbel Y, Finkelstein A, Halkin A, Birati EY, Revivo M, Zuzut M, et al. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis 2012;225:456-60. [Crossref]
  • 5. Yang YL, Wu CH, Hsu PF, Chen SC, Huang SS, Chan WL, et al. Systemic immune-inflammation index (SII) predicted clinical outcome in patients with coronary artery disease. Eur J Clin Invest 2020;50:e13230. [Crossref]
  • 6. Tang EW, Wong CK, Herbison P. Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts longterm mortality post acute coronary syndrome. Am Heart J 2007;153:29-35. [Crossref]
  • 7. Hu B, Yang XR, Xu Y, Sun YF, Sun C, Guo W, et al. Systemic immuneinflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. Clin Cancer Res 2014;20:6212-22. [Crossref]
  • 8. Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol 1983;51:606. [Crossref]
  • 9. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 2005;18:1440-63. [Crossref]
  • 10. Libby P. Mechanisms of acute coronary syndromes and their implications for therapy. N Engl J Med 2013;368:2004-13. [Crossref]
  • 11. Madjid M, Fatemi O. Components of the complete blood count as risk predictors for coronary heart disease: in-depth review and update. Tex Heart Inst J 2013;40:17-29. [Crossref]
  • 12. Bian C, Wu Y, Shi Y, Xu G, Wang J, Xiang M, et al. Predictive value of the relative lymphocyte count in coronary heart disease. Heart Vessels 2010;25:469-73. [Crossref]
  • 13. Cannon CP, McCabe CH, Wilcox RG, Bentley JH, Braunwald E. Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators. Am J Cardiol 2001;87:636-9. [Crossref]
  • 14. Tamhane UU, Aneja S, Montgomery D, Rogers EK, Eagle KA, Gurm HS. Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute coronary syndrome. Am J Cardiol 2008;102:653-7. [Crossref]
  • 15. Bozan MB, Yazar FM, Kale İT, Yüzbaşıoğlu MF, Boran ÖF, Azak Bozan A. Delta neutrophil index and neutrophil-to-lymphocyte ratio in the differentiation of thyroid malignancy and nodular goiter. World J Surg 2021;45:507-14. [Crossref]
  • 16. Bedel C, Korkut M, Aksoy F, Kuş G. Usefulness of immature granulocytes to predict high coronary SYNTAX score in acute coronary syndrome; a cross-sectional study. Arch Acad Emerg Med 2020;8:e73. [Crossref]
  • 17. Azab B, Shah N, Akerman M, McGinn JT Jr. Value of platelet/lymphocyte ratio as a predictor of all-cause mortality after non-ST-elevation myocardial infarction. J Thromb Thrombolysis 2012;34:326-34. [Crossref]
  • 18. Nikolsky E, Grines CL, Cox DA, Garcia E, Tcheng JE, Sadeghi M, et al. Impact of baseline platelet count in patients undergoing primary percutaneous coronary intervention in acute myocardial infarction (from the CADILLAC trial). Am J Cardiol 2007;99:1055-61. [Crossref]
  • 19. Budzianowski J, Pieszko K, Burchardt P, Rzezniczak J, Hiczkiewicz J. The role of hematological indices in patients with acute coronary syndrome. Dis Markers 2017;2017:3041565. [Crossref]
  • 20. Yang R, Chang Q, Meng X, Gao N, Wang W. Prognostic value of systemic immune-inflammation index in cancer: a meta-analysis. J Cancer 2018;9:3295-302. [Crossref]
  • 21. Zhong JH, Huang DH, Chen ZY. Prognostic role of systemic immuneinflammation index in solid tumors: a systematic review and metaanalysis. Oncotarget 2017;8:75381-8. [Crossref]

New Predictors in Determining the Need for Invasive Treatment in NSTEMI During the COVID-19 Pandemic? A Retrospective Study

Year 2021, Volume: 24 Issue: 1, 1 - 7, 01.04.2021

Abstract

Giriş: Noninvaziv yaklaşım, “Coronavirus Disease-2019 (COVID-19)” pandemisi sırasında akut ST yükselmesiz miyokart infarktüsü-akut koroner sendrom (NSTEMI-AKS) için ilk seçenek haline gelmiştir. Ancak bu hastaların çoğu girişimsel tedaviye ihtiyaç duyar. Bu çalışmada, girişimsel tedaviye ihtiyaç duyan GRACE risk sınıflandırmasına göre orta-yüksek riskli NSTEMI-AKS hastalarını ayırt etmede hematolojik inflamatuvar belirteçlerin olası rolü araştırılmıştır.

Hastalar ve Yöntem: Geriye dönük kohort çalışması olarak tasarlanan çalışmaya Ocak 2018-Aralık 2019 tarihleri arasında üçüncü basamak kardiyoloji kliniğinde NSTEMI-AKS tanısı ile koroner anjiyografi yapılan hastalar dahil edilmiştir. AKS hastaları (n= 276), dışlama kriterleri olan hastalar (n= 32) dışındaki sonuçlara göre invaziv tedavi (n= 217) ve medikal tedavi (n= 59) olmak üzere iki gruba ayrılmıştır. Hematolojik inflamatuvar belirteçler gruplar arasında karşılaştırılmıştır.

Bulgular: Nötrofil lenfosit oranı (NLR) (EAA: 0.637, %95 CI: 0.563-0.712, p= 0.001) ve sistemik immün inflamasyon indeksi (SII) (EAA: 0.622, %95 CI: 0.545-0.699, p= 0.004) NSTEMI-AKS’de girişimsel tedavi gerekliliğini öngörmüştür.

Sonuç: İnvaziv tedavi ihtiyacının bir göstergesi olabilecek NLR ve SII yükselmesinin, NSTEMI-AKS’li hastalarda patofizyolojik sürecin bir nedeni mi yoksa bir sonucu mu olduğu açık değildir. Bununla birlikte, yüksek NLR ve SII değerleri, COVID-19 pandemisi sırasında invaziv tedaviye ihtiyaç duyan NSTEMI-AKS hastalarını ayırt etmeye yardımcı olabilir. Bu çalışmanın sonuçları, NSTEMI-AKS için tedavi stratejisini belirlemede NLR ve SII seviyelerinin ideal kesme noktasını belirlemek için büyük ölçekli
çalışmalara olan ihtiyacı göstermektedir.

References

  • 1. Collet JP, Thiele H. The ‘Ten Commandments’ for the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2020;41:3495-7.
  • 2. Aktoz M, Altay H, Aslanger E, Atalar E, Atar I, Aytekin V, et al. Consensus Report from Turkish Society of Cardiology: COVID-19 and Cardiovascular Diseases. What cardiologists should know. (25th March 2020). Turk Kardiyol Dern Ars 2020;48:1-48.
  • 3. Romaguera R, Cruz-Gonzales I, Ojeda S, Jimenez-Candil J, Calvo D, Seara JG, et al. Consensus document of the Interventional Cardiology and Heart Rhythm Associations of the Spanish Society of Cardiology on the management of invasive cardiac procedure rooms during the COVID-19 coronavirus outbreak. REC Interv Cardiol 2020;2:106-11.
  • 4. Arbel Y, Finkelstein A, Halkin A, Birati EY, Revivo M, Zuzut M, et al. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis 2012;225:456-60. [Crossref]
  • 5. Yang YL, Wu CH, Hsu PF, Chen SC, Huang SS, Chan WL, et al. Systemic immune-inflammation index (SII) predicted clinical outcome in patients with coronary artery disease. Eur J Clin Invest 2020;50:e13230. [Crossref]
  • 6. Tang EW, Wong CK, Herbison P. Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts longterm mortality post acute coronary syndrome. Am Heart J 2007;153:29-35. [Crossref]
  • 7. Hu B, Yang XR, Xu Y, Sun YF, Sun C, Guo W, et al. Systemic immuneinflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. Clin Cancer Res 2014;20:6212-22. [Crossref]
  • 8. Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol 1983;51:606. [Crossref]
  • 9. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 2005;18:1440-63. [Crossref]
  • 10. Libby P. Mechanisms of acute coronary syndromes and their implications for therapy. N Engl J Med 2013;368:2004-13. [Crossref]
  • 11. Madjid M, Fatemi O. Components of the complete blood count as risk predictors for coronary heart disease: in-depth review and update. Tex Heart Inst J 2013;40:17-29. [Crossref]
  • 12. Bian C, Wu Y, Shi Y, Xu G, Wang J, Xiang M, et al. Predictive value of the relative lymphocyte count in coronary heart disease. Heart Vessels 2010;25:469-73. [Crossref]
  • 13. Cannon CP, McCabe CH, Wilcox RG, Bentley JH, Braunwald E. Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators. Am J Cardiol 2001;87:636-9. [Crossref]
  • 14. Tamhane UU, Aneja S, Montgomery D, Rogers EK, Eagle KA, Gurm HS. Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute coronary syndrome. Am J Cardiol 2008;102:653-7. [Crossref]
  • 15. Bozan MB, Yazar FM, Kale İT, Yüzbaşıoğlu MF, Boran ÖF, Azak Bozan A. Delta neutrophil index and neutrophil-to-lymphocyte ratio in the differentiation of thyroid malignancy and nodular goiter. World J Surg 2021;45:507-14. [Crossref]
  • 16. Bedel C, Korkut M, Aksoy F, Kuş G. Usefulness of immature granulocytes to predict high coronary SYNTAX score in acute coronary syndrome; a cross-sectional study. Arch Acad Emerg Med 2020;8:e73. [Crossref]
  • 17. Azab B, Shah N, Akerman M, McGinn JT Jr. Value of platelet/lymphocyte ratio as a predictor of all-cause mortality after non-ST-elevation myocardial infarction. J Thromb Thrombolysis 2012;34:326-34. [Crossref]
  • 18. Nikolsky E, Grines CL, Cox DA, Garcia E, Tcheng JE, Sadeghi M, et al. Impact of baseline platelet count in patients undergoing primary percutaneous coronary intervention in acute myocardial infarction (from the CADILLAC trial). Am J Cardiol 2007;99:1055-61. [Crossref]
  • 19. Budzianowski J, Pieszko K, Burchardt P, Rzezniczak J, Hiczkiewicz J. The role of hematological indices in patients with acute coronary syndrome. Dis Markers 2017;2017:3041565. [Crossref]
  • 20. Yang R, Chang Q, Meng X, Gao N, Wang W. Prognostic value of systemic immune-inflammation index in cancer: a meta-analysis. J Cancer 2018;9:3295-302. [Crossref]
  • 21. Zhong JH, Huang DH, Chen ZY. Prognostic role of systemic immuneinflammation index in solid tumors: a systematic review and metaanalysis. Oncotarget 2017;8:75381-8. [Crossref]
There are 21 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Original Investigations
Authors

Ekrem Aksu 0000-0003-1939-1008

Publication Date April 1, 2021
Published in Issue Year 2021 Volume: 24 Issue: 1

Cite

Vancouver Aksu E. New Predictors in Determining the Need for Invasive Treatment in NSTEMI During the COVID-19 Pandemic? A Retrospective Study. Koşuyolu Heart Journal. 2021;24(1):1-7.