2-Amino-(4;5;6)-substitüebenzotiyazol Türevlerinin Metal Kompleksleri ve Biyolojik Özellikleri Hakkında Literatür Çalışması

Year 2017, Volume: 1 Issue: 2, 78 - 94, 28.12.2017

Halil İlkimen

Abstract

2-Amino-4-(kloro;metil;metoksi)benzotiyazolün
(1-3) Mo(0), Co(II), Cu(II), Ag(I),
Cd(II), Hg(II), Rh(III) ve Pt(II) ile
2-amino-5-(etoksi;metil;metoksi)benzotiyazolün (4-6) Co(II), Cu(II), Zn(II), Ag(I), Hg(II), Sn(IV) ve Ge(IV) ile
2-amino-6-(bromo;etoksi;karboksi;kloro;metil;metoksi;
nitro;sulfamoyil)benzotiyazolün (7-14)
Cr(I), Mn(II), Fe(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Mo(IV), Cd(II),
Hg(II), Rh(I), Rh(III), Pd(II), Pt(II), Pb(II), Ru(III) ve In(III) metal
kompleksleri ve
2-amino-6-(bromo;kloro;metil;metoksi;nitro;sulfamoyil)benzotiyazol ile
asetilaseton, benzoyilaseton, dibenzoyilmetan, benzoyiltrifloroaseton,
2-benzoyil-1,3-indandion, 2,2’-bipridin, m veya p-nitrobenzoik asit,
5-nitroizoftalik asit, stearik asit, ve
2,6-piridindikarboksilik asitin karışık ligandlı metal komplekslerinin
[Mn(II), Fe(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) ve Cd(II)] yapıları ve
biyolojik özelliklerini anlatan çalışmalar literatürde gözlenmiştir. Bu
komplekslerinin antibakteriyel,
antikanser, antifungal, anti-inflamatuar, antitümör ve karbonik
anhidraz inhibisyonu gibi biyolojik
özellikleri bilinmektedir.

Keywords

2-Aminosubstitüebenzotiyazol, Metal Kompleksleri, Biyolojik Özellikler

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