Role of Negative-Pressure Wound Therapy in Deep Sternal Wound Infection After Open Heart Surgery

Abstract

Introduction: Mediastinitis is a devastating complication in open heart surgery. The most common treatments after debridement are rewiring with antibiotic irrigation. Vacuum assisted closure therapy is a recently introduced technique that promotes the healing of diffi cult wounds, including post-sternotomy mediastinitis. Patients and Methods: Forty one patients with deep sternal wound infection were divided into two groups based on the treatment method used. Twenty two patients with post-cardio to my deep sternal wound infection were treated primarily by vacuum assisted closure method (group A) and 19 patients with deep sternal wound infection who received closed mediastinal irrigation were treated with antibiotics (group B) between January 2006 and January 2010. Results: The two groups were compared. Three patients died during treatment in group B. The median healing time was signifi cantly shorter in group A (mean, 13.5 ± 3.2 days) compared to 18 days (mean, 21.2 ± 16.4 days) in group B (p< 0.001). Deep sternal wound infection showed no recurrences after the vacuum treatment, while 7 (24%) patients in group B suffered recurrences. Hospital stay was signifi cantly shorter in group A (median, 30.5 days; mean, 32.2 ± 11.3 days vs. median, 45 days; mean, 49.2 ± 19.3 days) (p= 0.001). Conclusion: A signifi cantly shorter healing time was confi rmed with vacuum assisted closure. Hospital stay remained signifi cantly shorter in group A (35 vs. 46 days).

Keywords

• Negative-pressure wound therapy; mediastinitis; sternum; surgical wound infection;wound healing.

Açık Kalp Cerrahisinden Sonra Derin Sternum Yara İnfeksiyonunda Negatif Basınçlı Yara Tedavisinin Rolü

Abstract

Giriş: Mediyastinit kalp cerrahisinde yıkıcı bir komplikasyondur. En sık tedavi şekli debridman sonrası yaranın tekrar kapatılması ve mediyastenin antibiyotikle irrigasyonudur. Vakum yardımlı kapalı tedavi yöntemi son zamanlarda ortaya çıkmış bir tedavi tekniği olup, sternotomi sonrası mediyastinitler gibi zor yaralarda iyileşmeyi kolaylaştırmaktadır. Hastalar ve Yöntem: Ocak 2006-Ocak 2010 tarihleri arasında derin sternal yara gelişen 41 hasta kullanılan tedavi yöntemine göre iki gruba ayrıldı. Mediyastinitli 22 hasta devamlı vakum destekli kapalı yöntemle tedavi edildi (grup A). On dokuz mediyastinitli hastaya antibiyotikle kapalı mediyastinal irrigasyon tedavisi uygulandı (grup B). Bulgular: İki grup karşılaştırıldı. Grup B'den üç hasta tedavi sırasında kaybedildi. Ortalama iyileşme süresi grup A'da (13.5 ± 3.2 gün), grup B'ye (21.2 ± 16.4 gün) göre belirgin olarak daha kısa idi (p< 0.001). Vakum tedavisi sonrası hastalarda nüks görülmezken, grup B'de 7 (%24) hastada infeksiyon tekrarlamıştır. Hastanede kalım süresi grup A'da ortalama 30.5 (32.2 ± 11.3) gün, grup B'de ise ortalama 45 (49.2 ± 19.3) gün olup, grup A'da belirgin olarak daha kısa idi (p= 0.001). Sonuç: Kapalı vakum sisteminde iyileşme süresi belirgin olarak kısa bulunmuştur. Hastanede kalım süresi grup A'da önemli oranda kısadır.

Keywords

• Negatif basınçlı yara tedavisi; mediyastinit; sternum; cerrahi yara infeksiyonu; yara iyileşmesi.

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